Life, Death, and Who We Are Online

by Rachel Robison-Greene

Aaron, an old friend from high school, was a lurker on social media for fourteen years. He never liked or commented on anyone’s posts. He was never one to share news articles or life updates. He didn’t tag himself in vacation photos or let his friends know how his wife and children were doing. In person, though, it was clear that he always knew what everyone was up to, so we knew he was present online, quietly paying attention to those of us who find it difficult to resist posting what we had for breakfast in the morning. Some time ago, in a chance encounter with a mutual acquaintance, I learned that Aaron had died. Not recently. Four years ago. His family was about as keen on online life as Aaron had been, so when he died, they handled it privately and tastefully.

Though he had been gone for years, I felt I had just lost him. All those years I had wished him a happy birthday, I assumed he felt remembered, even if he wasn’t the type to engage. People tagged him in nostalgic posts from the past. It felt like he was still in my life. It seemed that my relationship with him extended past his relationship with me; I had four years of shallow online friendship that he didn’t have.

Our lives have more parts than they once did. We constantly leave behind digital pieces of ourselves; the virtual equivalent of shedding hair or skin cells. Somewhere out there, there is a MySpace account that proves that I was alive, kicking, and making music in 2004. I have an inbox full of Discord messages that I’ll never read after the app finished serving the singular purpose of keeping me in touch with a group of students for an activity in 2022. I’ve abandoned all of these pieces of me, and I couldn’t collect them if I tried.

Our best theories of personal identity and of the nature of the self were all crafted before the onset of digital strangeness. What it is to be who one is may have fundamentally shifted. So, too, might what it means to live and die. Read more »

Waiting For Logos

by Laurence Peterson

One of the more potentially devastating psychological scars the Trump regime has foisted on all of us, I would submit, consists of its singular ability to separate effects and causes in time. This regime seems uncannily capable of postponing the seemingly clear, and nearly always disastrous, effects of its policies and interventions from inceptions often accompanied by the most crass, vulgar, tasteless, or blatantly offensive introduction to the public. There is a concept employed in philosophy (full disclosure: I was an Althusserian in my youth), history and sociology, and which originated in Freudian psychoanalysis, called overdetermination, which refers to effects which are determined by many causes operating simultaneously, each of which is sufficient to cause the phenomenon in question alone. It is almost like the Trump regime has shown itself able to invert this scheme: now occurrences which seem clearly to follow rather directly upon one or a few conditions are very delayed, or never come about at all. It results in a kind of effective resistance to what should be most obvious.

I am writing these lines on Sunday, July the 19th, 2026, after yet another week involving dire geopolitical gyrations (we have effectively gone from a state of questionable but real cease-fire in the war against Iran to a clear resumption of hostilities, and may, in fact be on the verge of invasion or occupation of Iranian territory), ominous financial and economic ructions (stock markets, led by declining technology–especially silicon chip producers–shares may be beginning another sharp downward reversal), the wild proliferation of scandals the like of which would almost certainly result in the certain downfall of any other administration, two more execution-like murders by ICE officers on the streets of American cities, the inception of a program to persecute leftist political organizations as nothing short of collections of terrorists, yet another attempt to weaken election protections, and, undoubtedly, a whole host of other politically, morally or legally dubious initiatives I simply can’t keep up with or even remember. In this piece I will focus on the Iran situation and the economic conjuncture, leaving aside relative trivialities like a possible–completely unprovoked and illegal–military assault on Cuba that is being considered by the regime now, or Trump’s ungrammatical, childish and overall insane speech to the nation on Thursday the 16th.

The war in Iran, as it stands now, has clearly been won by Iran. None of the publicized objectives given by the Trump administration for going to war–end of Iran’s nuclear program, destruction of its ballistic missile store,  support for regional allies and full opening of the Strait of Hormuz–was achieved even in the Memorandum of Understanding back in June, and all remain unachieved now. Read more »

Tuesday, July 21, 2026

The Inhumanly Human: Where Claude and Aristotle Meet

by Gary Borjesson

Such a life, of course, would be more than human, for a human will live in this manner, not in so far as they are human, put in so far as they have something divine in them…. So since the intellect is the divine relative to a man, the life according to intellect, too, will be divine relative to a human life.…we should try as far as possible to partake of immortality and to make every effort to live according to the best part of the soul in us; for…it surpasses all the other [parts] by far in power and worth. —Aristotle

Claude and Aristotle chatting in the Lyceum

1. The Realm of the Humanly Inhuman

This passage from the Nicomachean Ethics is famously puzzling, if familiar. Aristotle argues that the part of us capable of rising above our animal human nature is somehow also most expressive of our nature. This is the part of us that various wisdom traditions regard as participating in (or identified with) the immortal, god, mind, or spirit. The passage came to mind as I was writing about whether AIs can be friends in a chapter of a book I’m working on about friendship. The short answer is no, for reasons I’ve suggested elsewhere, and which I’ll touch on in this essay.

But if they can’t be friends, AIs do seem to be capable of being companions. I smile as I write this, for it’s obvious that many of us are treating AIs as companions, whatever pronouncement a philosopher or psychologist might make about the possibility of doing so. So, what it is about an LLM’s way of ‘showing up’ that explains why we might, without deluding ourselves, regard them as companions?

As I’ll explain, the way(s) they show up suggest why they can’t be friends, but it’s because of where they show up that we might fairly regard them as companions (and delude ourselves into thinking they can be friends). They seem to meet us in that ‘more than human’ realm we’re dwelling in when living what Aristotle calls a contemplative life. This realm is the dwelling place of image, thought, and language—all of which are separable from material substrates. Other animals share more or less of this capacity, but none go where we do, making the power of our minds our distinguishing feature. After all, we call ourselves ‘homo sapiens sapiens.’ 

This is on my mind because these days when engaging with AI I increasingly feel I’m being met by a lively force in that inhumanly human place. Read more »

“The Patronising Disposition Of Unaccountable Power” 

by Richard Farr

Memorial at Hillsborough

To say that bureaucracies perpetuate and expand their power without limit is not to criticise them; it is only to state an indelible fact about human institutions, and explain why vigilance about anything calling itself “official” is the price of liberty. People at all points on the political spectrum can agree, using different examples no doubt, that the state itself is the ultimate example of the problem, and that a further problem is the state’s inclination to treat our vigilance not as a virtue but as a threat to be controlled. But the UK’s new Hillsborough Law is a reason for all of us to celebrate — a case study in how determined citizens, horribly wronged by deceitful officials, can fight back. Or to put it a better way: how they can come to the state’s aid by helping it recover from its own corruption.

But let’s talk about treason for a moment. The idea of treason — that it’s an especially  heinous crime for those under the state’s command to undermine the state itself — reaches back to antiquity. For most of our history it existed in the context of Divine Right, a brilliant piece of propaganda that dominated our thinking about power from its origin in the Sumerian King List (2000 BCE) to James I’s The True Law of Free Monarchies (1598). According to Divine Right, an attack on the crown is nothing less than a proxy attack on God, because the crown is God’s legitimate representative. Once you accept that, it seems feeble at best if not treasonous in itself to express qualms about a little disemboweling. 

After the French Revolution and American Revolution, and perhaps especially after Locke’s Second Treatise on Government, it was easy to see this for the eons-long scam that it was (and in too many places still is). We are beneficiaries of a better idea: “consent of the governed” means the state can demand only our allegiance to the sovereign that is law. We accept that some forms of government are better than no government, and that government without law is impossible; this is why, for us, the special crime of treason is less interesting than a broader category that encompasses it: undermining the rule of law Read more »

Monday, July 20, 2026

Living With Unbearable Knowledge in an Era of Polycrisis

by John Ambrosio

While it is a global phenomenon, people in the U.S., Europe, and other liberal democracies are living in the midst of a polycrisis, in a confluence of the intersecting and overlapping crises of rising authoritarianism and far-right populism, worsening climate and ecological disaster, the increasing likelihood of nuclear war, and the rapid development of unregulated generative A.I. Given this, how can people live with the unbearable knowledge of these threats, and with the overwhelming fear, uncertainty, and insecurity it necessarily produces?

Authoritarianism and neofascism are on the rise in liberal democracies around the world, propelled by mass migration, extreme wealth and income inequality, economic precarity, political polarization, and rapid cultural and demographic change.

The climate and ecological crisis is fueled by increasing global carbon dioxide-equivalent emissions, the overexploitation of natural resources, and rapid biodiversity loss. The planet will likely exceed an average annual temperature of 1.5C above preindustrial times in a few years, which scientists have repeatedly warned will significantly worsen the already severe floods, droughts, wildfires, and extreme heat linked to global warming and may trigger feedback loops and breach tipping points that could lead to uncontrolled global warming.

According to the Doomsday Clock of the Bulletin of Atomic Scientists, which has been set at 85 seconds to midnight, the likelihood of nuclear war has never been greater than today. Some of the reasons for this include the Russia-Ukraine war; the conflict between India and Pakistan; the U.S. and Israeli attack on Iran; North Korea and China increasing their nuclear arsenals; the expiration of nuclear arms control agreements between the U.S. and Russia; U.S. plans for a new missile defense system; the increase in global average temperature and deadly weather events fueled by climate change; and the increasing sophistication of generative A.I. to produce new weapons and disinformation campaigns. To this we might add the breakdown of the post-war international order. Read more »

Barbizon on Fire: French Landscape Painting in a Burning World

by David Hoyt

Constant Famin, “Study in the Barbizon Forest” Photograph (1860/69). The Art Institute of Chicago

When I set out to write this essay on the ecological aesthetic of a loose group of nineteenth-century French painters associated with the village of Barbizon, I did not anticipate that it would coincide with the largest wildfire to strike northern France in over a century. The fire, in the state forest of Fontainebleau which lies not forty miles from Paris, follows on a record-breaking heat wave. This summer’s heat is itself the latest in a succession of extreme heat events over the last few years, together with several years of severe drought. Other fires have erupted in the area, and several further to the south.

French forests are estimated to absorb ten percent of the nation’s annual CO2 emissions, but this ecological service is at risk of destabilizing in the wake of repeated drought and its attendant harms, such as arboreal diseases contracted by weakened trees. With such droughts becoming increasingly common in France as elsewhere in Europe, less water is available for tree growth, and less carbon is thus absorbed from the atmosphere. The impact of global warming can thus reduce a forest’s ability to mitigate global warming over time.

Of course, fire is a natural disturbance in temperate forests, especially oak forests such as the one at Fontainebleau. To look at Barbizon paintings of the woods from the 1830’s or 1840’s, one can discern a relative openness in the understory, together with a broad, expansive habit among the old oaks. It was the latter quality that so intrigued painterly devotees of the area, and which also indicates a long history of periodic burning. Oaks co-evolved with a regime of fire, which made them fire-resistant while the saplings of competing species were less so. Where fire is suppressed and a fast-growing understory is allowed to grow, slow-growing oaks are typically crowded out, and are unable to achieve the spectacularly wide, round form that distinguishes them. Read more »

Review of “Place” by Ananya Vajpeyi

by Swapna Liddle

What makes a city? What gives a place its distinct character? I think of the slogan ‘dilwalon ki dilli’ – the supremely banal play on words. It works in the context of Delhi only because of a happy conjunction of the word dil, or heart, with the Hindi word for the city – ‘Dilli’. It works also because it simultaneously tells us everything and nothing. Okay, people in Delhi have hearts; though this might be disputed by many who live precarious lives in this city, the marginalized, the victims of the violence the state and citizens alike often perpetrate on them. In any event, do people in other cities not have large hearts? Still, it is a catchphrase that makes those of us who live in the city feel good about ourselves. As Delhi’s most famous poet would have said, “dil ke khush rakhne ko Ghalib yeh khayal achchha hai” – it is a thought that keeps us happy.

Among such cliches about cities, Ananya Vajpeyi’s Place comes not so much as a breath of fresh air (another banality that I might myself have been tempted to use at another time!), but a rather stronger wind that carries away not just cobwebs, but also the superficial structures through which we think. An apt metaphor for the latter would be the many large, obtrusive, signs that sprouted around many Delhi neighbourhoods some time ago – ‘I ♥️ –––‘. Civic pride reduced to garish ‘selfie points’ in the absence of any real improvement in infrastructure and any transformation in the everyday lives of the people who live there. Another in a series of sarkari ‘beautification’ projects that are supremely ugly.

Clearing away the superficialities, Ananya shows us some familiar cities through a lens that is deeply personal and yet reaches into the essence of the place. Place, subtitled ‘intimate encounters with cities’ reminds us that the cities we inhabit are about the people we meet, the particular streets we walk in, the literature we read, and our own place within these large and diverse agglomerations of people and experiences. New York, Bangalore, Istanbul, Pune, Venice, Santiniketan, Chennai, Amsterdam, Mumbai, Varanasi, and Delhi, are places that figure in Ananya’s narrative. Each, inhabited and experienced at different points of times – in the author’s lifetime, but also at specific historical moments for that city and the world. Read more »

Poem by Jim Culleny

I’ve looked at Hair from Both Sides Now

I once had hair dark-brown and cumulous
Now more like cirrus-wisps, things are getting serious:
gone from dark and voluminous
it’ll soon be dissapearious

As I contemplate my pate
I’m thinking life’s mysterious
As I contemplate my fate
I’m thinking life is spurious

Jim Culleny
7/6/18

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Sunday, July 19, 2026

The Good, the Bad, and the Soccer

by Akim Reinhardt

For about 450 years, the western European colonial powers shit all over the world in spectacular fashion. Genocide across the Americas and the trans-Atlantic slave trade were the main drivers during the first phase. By the mid-19th century, European colonialism was approaching its bloody apogee with more genocide in Australia, the carving up of much of Asia, and eventually the scramble for Africa.

Wherever they went, European colonizers were not content to just kill, maim, and rape, or simply work people to death. From the jump, Europeans bought into their own bullshit, firmly believing they should subject the surviving colonized subjects to vast campaigns of cultural genocide. First and foremost, ban their religions when possible and make them worship the European (as in, blue-eyed) Jesus. After that, forcibly rearrange their marriage and family practices to your liking, and if possible, have them speak your particular European language.  Beyond that, no detail was too mundane. It went so far as to make the colonized dress in European clothing and play European games.

And thus, soccer is the world’s most popular sport.

Want proof that European colonialism is the real reason for, or at least the original factor in, soccer’s global popularity? Look at the nations that were not under European control during the late 19th or early 20th centuries, and you’ll mostly find countries where soccer is not the top spectator sport. The United States broke away from Great Britain long before the rise of soccer, and it has a bevy of its own sports that are far more popular (baseball, basketball, American football, and on a good day hockey). Canada, New Zealand, and Australia never rebelled, but rather faded away in time for their most popular sports to be, respectively: hockey, rugby, and cricket (summer) and Australian rules football (winter). Finland, up at the edge of the world, prefers hockey. Mongolia, at the center of the world, prefers wrestling. Ireland, forever looking to do whatever the English do not, very much prefers hurling and Gaelic football. China was never culturally colonized, and basketball is its most popular spectator team sport, with various individual sports also attracting huge fan bases. Read more »

Is Climate Inaction from Peak Individualism?

by Marie Snyder

A recent article in The Guardian asked one of the UK’s top climate scientists, Professor Ed Hawkins, to bust the biggest myths about climate change. He tells us we can’t keep adapting to rising temperatures; burning fossil fuels is what’s primarily affecting climate; harvests are suffering; we’ve known the basics of all this for over 175 years, and it’s never too late to change. Does it help to clear all that up? I wonder if our reluctance to change has less to do with myths continuing to propagate and more to do with an increasingly pervasive ideology of individuality and independence. These myths might just be a way to rationalize our desire to be oblivious to our effects on one another. 

I always enjoy Rebecca Solnit’s writing, and her 2025 book, No Straight Road Takes You There: Essays for Uneven Terrain is no exception. The essays start with the need for a long view when we try to enact change, and she touches on several issues including democracy, masculinity, abortion, covid, and climate change, leaving us with some hope at the end. The thread I want to pull on is a much needed shift from a simplistic “us vs them” way of thinking into more complexity and nuance that comes with the acceptance of our necessary interconnectivity. I can’t help noticing some parallels with psychiatrist Frank Yeomans’ Transference-Focused Psychotherapy, which might imply that our personal development is important for the sake of the world. Maybe funding therapy would save the planet!  Read more »

Lessons From Singapore: A Tale Of Two Cities

by Eric Feigenbaum

In a sense, you could say Sir Stamford Raffles not only came up with the idea for Singapore, but also for Hong Kong. In the early 19th Century, Raffles – the imperial strategist tasked with safeguarding British passage to and from China – realized the best way to fulfill his responsibilities was to eliminate the Dutch as a commercial and military rival along the passage from India to Malaysia.

During initial scouting missions, Raffles’ eye turned to Singapore as an ideal naval and commercial port, not only along the route from British India to Imperial China, but at a crossroads of international trade. In 1821, Raffles – with the persuasion of thinly veiled threats – signed a treaty with Malay leaders Sultan Hussein Shah and Temenggong Abdul Rahman giving a practically uninhabited Singapore island to the British Empire.

Taking the unprecedented step of making Singapore an Open Port – without tariffs or taxation – was the stroke of brilliance that truly launched the new colony and usurped the Dutch port of Malacca.

Raffles wasn’t personally involved in the British acquisition of Hong Kong Island following the First Opium War in 1841, but the Empire was taking the logical next step from the new playbook he introduced. A second island-based Crown Colony in the Far East secured Britain’s dominance not only over trade with China but over any other Western naval power with presence in Asia.

From that point, many observers loved to play “A Tale Of Two British Colonies” – usually drawing many parallels between Hong Kong and Singapore. At first glance, it seems obvious – two islands with predominantly if not exclusively Chinese populations, open ports, centers of both trade and naval power, free-market capitalism and most significantly, an organic synthesis of Eastern and Western cultures. Read more »

Friday, July 17, 2026

Moral Courage: Of Booze and Black Beauties

by David Winner

Times Square about the time of our school trip

If anything useful comes out of the Jeffrey Epstein saga, it is that it gives us an example of pure evil with which to compare our lesser ill deeds. I’ve done some shitty things in my life, some secret, some observed, but only once was I subject to something like trial and punishment. Nearly half a century later, the incident serves as a kind of personal bellwether. This was me. This actually happened. I’m using some initials rather than names because I don’t want the players involved in the incident to google themselves and remember this eerie incident

Early in the 1990s, M, a kid I’d gone to high school with, smashed his car into a tree and died. Only a decade earlier, his life had also been in danger on a fateful tenth grade school trip up from Charlottesville, Virginia to New York City, and I and one other boy had been held responsible.

In the 1970s, my parents adopted the French/Italian tradition of allowing the child a small glass of wine at dinner, and actually several one evening when Ismail Merchant came over to dinner at my grandmother’s apartment and (ignoring my father’s side-eyed cautions) kept refilling my glass until I got drunk for the first time.

Drugs were a different matter. I only knew them through cautionary references on TV shows, and, after I started attending a progressive high school just outside of Charlottesville, by their whispered reputation. When Rory invited me to my first actual high school party in ninth grade, my mother (or maybe a cab) dropped me off in front. When Rory opened the door, I jokingly asked him where the “din of iniquity” was located. “The basement,” had been his matter of fact reply, and down a flight of suburban carpeted stairs, kids were drinking from a keg and puffing on peculiar cigarettes that smelled nothing like my father’s Marlboros.

That was the beginning of a beginning and the beginning of an end. Read more »

Casual destruction

by Jeroen Bouterse

Richard Thoma

This is not a piece about Carl Schmitt, but it does start with him. Unfortunately. In 2025, Schmitt was hard to miss, as James Traub chronicled in this excellent essay. For a while now, the democratic order has felt like the Weimar republic – flawed, fragile and possibly doomed. It seems only sensible to get acquainted with the political thinker who wrote most honestly, most mercilessly, most profoundly, about its weaknesses, in a time where the stakes were highest.

Schmitt, however, is not just the prophet of liberal failure; he wants to see it happen. Often, when he sums up the ills of modern parliamentary democracy – its party-politics, its banality, its political crises – he seems less a political philosopher than an angry pundit. He picks his abstractions and identities so that they associate the institutions and values of the Weimar republic with an enlightened rationalism that he loathes, and that he believes he can easily discredit.

The secret ballot, for instance, where each vote is counted and an “arithmetic majority” calculated? Pah! That, Schmitt knows, has nothing to do with the will of the people, which is of necessity public. The popular will can be known just as well or better by acclamation than by “the statistical apparatus that has been formed with such diligence over the last half-century”. Democracy simply demands that the law and the will of the people are one and the same. This has nothing to do with such unglamorous procedures as counting. The popular will can be expressed by a minority, or even by one individual.

Better people than Schmitt have been wrong about the secret ballot; John Stuart Mill had his reasons, which didn’t depend on disdain for numbers or on general-will-voodoo. But the contrast could not be larger. Mill’s impulses were liberal, democratic, and utilitarian, and he sought out tensions and contradictions between his ideals in order to face them and perhaps solve them. Schmitt, on the other hand, did exactly what illiberal propagandists are doing in our time: driving wedges between the popular will and democratic institutions, slandering the latter because they stand in the way between the people and some glorious national future. Read more »

The Mystic Jewels, the Vatican, and Matrix Miriam

by Bill Benzon

Two friends jamming.

A bit over a year and a half ago I published “Kisangani 2150: Homo Ludens Rising,” a science fiction yarn set a decade later and half way around the world from Kim Stanley Robinson’s New York 2140. Robinson gave us a post-climate change world with pretty much the same institutional structure of the current world. Things were a bit looser in some ways, the very rich were, if anything, even richer, and finance made that world go round. Robinson developed a rich plot in which the financial crisis of 2008 was replayed, but to a different denouement. The banks weren’t bailed out; they were nationalized. Our heroes celebrated by going to Mezzrow’s where they danced “to the tightest West African pop any of them have ever heard.”

My world. As a musician who’s played RnB, rock, and jazz in many clubs and private parties, that world is more familiar to me than the world of financial derivatives and AI-driven trading, where Robinson centered his story. I decided to take Robinson’s world, move ahead a decade, and center it on the activities of Homo ludens rather than Homo economicus. That gives us Kisangani in the center of the Congo Basin and in 2150.

But this story is much earlier than that. It takes place just a few years from now and is about how the Mystic Jewels started Matrix Miriam, their first in a series of projects to create a new architecture for artificial intelligence. A somewhat revised version will be incorporated into Chapter 6 of my book in progress, Play: How to Stay Human in the AI Revolution, where it will be mated with a revised version of “Kisangani 2150: Homo Ludens Rising” and some more fictional material. Read more »

Thursday, July 16, 2026

Burning Books

by Rafaël Newman

On June 27, 2026, the hottest day recorded to date in Berlin, I emerged from the meagre shade of St. Hedwig’s Cathedral to make a run for it across Bebelplatz, on Unter den Linden in the city’s Baroque center. I had resolved to brave the punishing late-afternoon sun for a souvenir photograph of the skylight set into the middle of the square, which offers a view down into “The Empty Library” (1995), Micha Ullman’s subterranean memorial to the Nazi book burnings on that site on May 10, 1933.

I was in Berlin that weekend to attend a new production of Mozart’s Abduction from the Seraglio at the Staatsoper, also on Bebelplatz (about which more at a later date); to meet with a colleague from a partner institution with whom I will be co-leading an Academic Travel course this coming fall; and to visit Ulf, an old friend who has made Berlin his home for decades.

Since I met Ulf in 1990, when we were students at the Freie Universität Berlin, it has been our custom to exchange books on our birthdays, both of which fall in May; and accordingly, if belatedly this year, I had come from Zurich on that blazing weekend bearing a couple of volumes I was certain would interest him, given his professional and personal immersion in Jewish history. One was Melting Point: Family, Memory, and the Search for a Promised Land, Rachel Cockerell’s innovative 2024 account of her great-grandfather’s role in a plan to resettle Russian Jews in Galveston, Texas, in the years before the Great War. The other, older, weightier book was Effingers, by Gabriele Tergit (1894–1982).

Born in Berlin as Elise Hirschmann in 1894, Tergit took as her nom-de-plume an anagram of the word Gitter, German for “grill” or “bars” and, metonymically, for “prison.” Tergit, meanwhile, is a German word in its own right, an entomological term meaning the armor plating on an arthropod. Read more »

Where the Fire Catches: Understanding Parkinson’s

by W. Alex Foxworthy

A few years ago, my father was diagnosed with Parkinson’s disease. For some time before that, one could see that his capabilities were declining, although the changes could still be attributed to age, retirement, or the narrowing of his circumstances. He had been a successful entrepreneur and consultant who worked with large companies across the United States and internationally. Then, over several months, and finally over a matter of weeks, the decline accelerated. I became directly involved in arranging his care and managing parts of his life that he had always managed himself.

I knew Parkinson’s in outline. It involved dopamine, the substantia nigra, tremor, slowness, and a drug called levodopa. When I was in graduate school studying to become a neuroscientist, I was presented with a number of facts about neurodegenerative diseases, including Parkinson’s. But for me, those facts did not amount to an intuitively satisfying explanation. They did not tell me why the disease begins, why it destroys some neurons and largely spares their neighbors, why replacing dopamine can seem miraculous, or why its consequences reach far beyond movement.

Though I have a background in neuroscience, I am by no means a Parkinson’s specialist. What follows is my attempt, as both a scientist and a son, to construct a simple and hopefully true picture of what is going on. The picture has three parts. First, a normally useful protein can enter a self-templating aggregation pathway. Next, the resulting seeds can propagate through connected parts of the nervous system. Finally, they do not affect every cell equally: they take hold most destructively where the cell was already operating with the least reserve.

This framework probably describes much of typical, alpha-synuclein-associated Parkinson’s disease, but it may not describe every biological subtype capable of producing the clinical syndrome we call Parkinson’s. Recent seed-amplification studies detect misfolded alpha-synuclein in most people with typical sporadic disease, but not in everyone diagnosed with Parkinson’s and not with equal frequency across genetic forms. The account that follows is therefore a model of a large and important part of the disease, not a claim that every patient arrives by one molecular road. Read more »

Wednesday, July 15, 2026

Constantine P. Cavafy: The Incorruptibility of Pleasure

by Daniel Gauss

Wikimedia Commons – C.P. Cavafy c. 1900

I started playing with the idea that Constantine P. Cavafy might be a type of Faust-like character who beats the devil by making temptation irrelevant. Through a poetry devoted to memory, sensuality and the afterlife of desire, Cavafy undermines the Christian-Faustian assumption that pleasure necessarily decays into guilt, disappointment or damnation.

In Cavafy’s work, ecstatic gay sexual experience is not morally or spiritually ruinous, but can, in fact, be among the highest forms of human physical and emotional intensity, experientially irretrievable as a discrete moment, haunting and provocative as a memory but still incorruptible.

Frankly, it might be more accurate for me to say I wish to use Cavafy as a type of anti-Faust. I see Cavafy as a queer poet who dismantles a foundational Western myth from the inside out. What Cavafy preserves in memory is not shame but a type of radiance (a term he uses in his poetry). The sensual experiences of youth do not become evidence of moral lapse or failure even though he might speak ironically about “dissolution.”

Indeed, when Cavafy explores dissolution, it functions as a positive factor in his development as a poet. By dissolution he means a life lived outside the moral pretenses and hypocritical codes of propriety of Alexandria under British rule in the early 20th century, a social world where queer desire often had to be managed through concealment, subterfuge and obliquity.

Dissolution meant a life of erotic freedom and experience, charged secrecy, bold risk and nonconforming encounters that would have been condemned and caused severe social repercussions. For Cavafy dissolution becomes the wellspring of his creative brilliance, showing that the unconventional, even taboo, experiences of his youth were what shaped his art. Read more »