This Meal Might Bring You to Tears

Kristen French in Nautilus:

Most of us would say we taste food with our tongues. Charles Spence has spent decades showing that we eat with our eyes, our ears, our fingertips, even our emotions. An experimental psychologist at Oxford University, Spence has learned that when we sit down for a meal, all of our senses come to the table, and some of them have unexpected effects. Heavier cutlery, for example, makes a meal more pleasurable, he has found, and flavors in space are often duller. Foods that sound better taste better, too: In his infamous “sonic chip” experiments, he found that the louder the crunch of your Pringles potato chip, the fresher it tastes, work that won him a 2008 Ig Nobel Prize (which celebrates real science with a side of humor).

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Single Injection Transforms the Immune System Into a Cancer-Killing Machine

Shelly Fan in Singularity Hub:

With just a single injection, a new treatment transforms immune cells in cancer patients into efficient tumor-killing machines. Now equipped with homing beacons, the cells rapidly track down and destroy their cancerous foes.

The shot is based on CAR T cell therapy, a breakthrough that uses genetic engineering to supercharge cancer-fighting T cells. Since its first FDA approval in 2017, CAR T has vanquished some deadly cancer cases with a one-and-done treatment.

But the technology is costly—for both body and wallet. CAR T cells are usually made outside the body in a lab. Patients undergo chemotherapy and other harsh treatments to make room for the enhanced immune cells, taxing an already ailing body with side effects. Making CAR T cells also takes precious time, and unfortunately, the clock often runs out.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Wednesday, December 24, 2025

From ‘Mona’s Eyes’ to ‘Theo of Golden’: This Year’s Surprise Hit Novels

From The New York Times:

When Allen Levi, a musician who had written scores of songs over his career, began writing his first novel, his plan was to finish it and stick it in a drawer. “I just wanted to see if I had the muscle to write a piece of long fiction,” he said. The resulting book, “Theo of Golden,” is about an older man who moves to a city in Georgia and begins buying 92 pencil portraits off a coffee shop wall to return them to their subjects and “rightful owners.” After a group of Levi’s friends read the novel and encouraged him not to let the manuscript molder, he self-published it through Amazon in the fall of 2023.

“Theo of Golden” became a word-of-mouth smash hit. It sold 3,000 copies in 2023, then 24,000 in 2024. This year, sales exploded, prompting Atria to buy rights to the book. It has sold more than 300,000 copies this year. The book opens with a dedication to Levi’s friend Cubby Culbertson: “As a token of gratitude for our long friendship and a reminder, just between us, that you promised to buy a hundred copies of the book if I dedicated it to you. Will that be cash or charge?”

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

One Battle After Another: Paul Thomas Anderson’s thrillingly helter-skelter counterculture caper

Peter Bradshaw in The Guardian:

One of the great creative bromances has flowered again: Paul Thomas Anderson and Thomas Pynchon. Having adapted Pynchon’s Inherent Vice for the screen in 2014, Anderson has now taken a freer rein with his 1990 novel Vineland, creating a bizarre action thriller driven by pulpy comic-book energy and transformed political indignation, keeping his pedal at all times welded to the metal.

It’s a riff on the now recognisable Anderson-Pynchonian idea of counterculture and counter-revolution, absorbing the paranoid style of American politics into a screwball farcical resistance, with a jolting, jangling, nerve-shredding score by Jonny Greenwood. It’s partly a freaky-Freudian diagnosis of father-daughter dysfunction – juxtaposed with the separation of migrant children and parents at the US-Mexico border – and a very serious, relevant response to the US’s secretive ruling class and its insidiously normalised Immigration and Customs Enforcement (Ice) roundups: the toxic new Vichyite Trump enthusiasm.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

The Bible says little about Jesus’ childhood – but that didn’t stop medieval Christians from enjoying tales of him as holy ‘rascal’

Mary Dzon in The Conversation:

‘Christ Discovered in the Temple,’ by Simone Martini (1342). Google Cultural Institute/Walker Art Gallery via Wikimedia Commons

After its account of Jesus’ birth, the Bible is almost entirely silent on his childhood. Yet legends about Jesus’ early years circulated widely in the Middle Ages – the focus of my 2017 book. While the detail of the ox and ass is quite familiar to many Christians today, few are aware of the other striking tales transmitted by the apocrypha.

The Bible does include one famous scene from Jesus’ youth: the incident when 12-year-old Jesus stayed behind at the Jewish temple in Jerusalem, unbeknownst to his parents. Searching for him with great anxiety, they find him conversing with religious teachers, both asking questions and astounding them with his answers. Fourteenth-century painter Simone Martini’s “Christ Discovered in the Temple” portrays him standing before his parents with crossed arms – a stubborn youth, apparently unapologetic about making them worry for days.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Waymo hits 2,000 vehicles while human drivers lose 6.9% pay

Daniel Abreu Marques at The AV Market Strategist:

Waymo’s co-CEO Tekedra Mawakana made a striking prediction this week:

You’re going to start seeing our cars in a lot of cities. If you think about our business in terms of scale, we’re currently giving hundreds of thousands of rides every week and, in all likelihood, by the end of next year, we will be offering around one million rides per week.

If Waymo hits anything close to that run-rate, the U.S. ridehail map changes.

The SF Examiner reports that Waymo now operates over 2,000 commercial vehicles across the U.S., with ~800 deployed in the Bay Area alone, another ~500 in Los Angeles and ~400 in Phoenix.

We already know Washington DC, Miami, and New York City are in the pipeline, with data collection underway in Houston, Orlando, San Antonio, Las Vegas, and San Diego. The company has even extended its reach internationally to Japan, indicating global ambitions that stretch well beyond American cities.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

As British as Fish and Chips

Dan Gardner at PastPresentFuture:

This has been a year in which terrible ideas buried and forgotten rose from the dead and ate many brains.

Tariffs-on-everything. Vaccines are poison. Fascism. Anti-Semitism. Hitler’s not so bad. And of course, ethnic nationalism, the idea that only people who share a common ancestry and culture can create a strong country. That particular zombie is even spreading across the United States, a country that never had a shared common ancestry and culture in its entire long, successful history.

Inevitably, I’ve found myself arguing with ethnic nationalists on social media, which is invariably a depressing experience. But the British zombies are the worst. “A thousand years of ethnic stability now destroyed by immigration,” is how one summed up British history to me.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Wednesday Poem

Christmas Mail

Cards in each mailbox,
angel, manger, star and lamb,
as the rural carrier,
driving the snowy roads,
hears from her bundles
the plaintive bleating of sheep,
the shuffle of sandals,
the clopping of camels.
At stop after stop,
she opens the little tin door
and places deep in the shadows
the shepherds and wise men,
the donkeys lank and weary,
the cow who chews and muses.
And from her Styrofoam cup,
white as a star and perched
on the dashboard, leading her
ever into the distance,
there is a hint of hazelnut,
and then a touch of myrrh.

By Ted Kooser

Enjoying the content on 3QD? Help keep us going by donating now.

Tuesday, December 23, 2025

The Harder Truths of True Crime

Phil Christman at The Hedgehog Review:

John J. Lennon is, at the moment, probably this country’s foremost imprisoned journalist. This title won’t be taken from him any time soon, not because there aren’t many talented and inquisitive people in prison but because the barriers to entry are so nearly impassible. A journalist’s life is a daunting prospect these days even to a person with freedom of movement, a real computer, the ability to make phone calls in private. Lennon’s new book, The Tragedy of True Crime, concludes with an author’s note that describes the makeshifts that he and his supporters have had to adopt so he can fulfill the most basic parts of an author’s job:

Receiving a 100,000-word work-in-progress manuscript in prison is harder than you may think, especially when that prison system is dealing with a K2 crisis. The drug looks like a regular piece of paper to the unknowing eye, but one sheet sprayed with K2 chemicals is worth about $1000 in prison.…

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

The Chinese finance whizz whose DeepSeek AI model stunned the world

Elizabeth Gibney in Nature:

In January this year, an announcement from China rocked the world of artificial intelligence. The firm DeepSeek released its powerful but cheap R1 model out of the blue — instantly demonstrating that the United States was not as far ahead in AI as many experts had thought.

Behind the bombshell announcement is Liang Wenfeng, a 40-year-old former financial analyst who is thought to have made millions of dollars applying AI algorithms to the stock market before using the cash in 2023 to establish DeepSeek, based in Hangzhou. Liang avoids the limelight and has given only a handful of interviews to the Chinese press (he declined a request to speak to Nature).

Liang’s models are as open as he is secretive. R1 is a ‘reasoning’ large language model (LLM) that excels at solving complex tasks — such as in mathematics and coding — by breaking them down into steps. It was the first of its kind to be released as open weight, meaning that the model can be downloaded and built on for free, so has been a boon for researchers who want to adapt algorithms to their own field. DeepSeek’s success seems to have prompted other companies in China and the United States to follow suit by releasing their own open models.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

The Untold Story of How Jeffrey Epstein Got Rich

David Enrich, Steve Eder, Jessica Silver-Greenberg, and Matthew Goldstein in the New York Times:

One evening in early 1976, a bushy-haired Jeffrey Epstein showed up for an event at an art gallery in Midtown Manhattan. Epstein was a math and physics teacher at the city’s prestigious Dalton School, and the father of one of his students had invited him. Epstein initially demurred, saying he didn’t go out much, but eventually relented. It would turn out to be one of the best decisions he ever made.

At the gallery, Epstein bumped into another Dalton parent, who had heard tales of the 23-year-old’s wondrous math skills. The parent asked if he’d ever thought about a job on Wall Street, according to an unreleased recording of Epstein and a document prepared by his lawyers. Epstein was game. The parent dialed a friend: Ace Greenberg, a top executive at Bear Stearns. Epstein, the friend told Greenberg, was “wasting his time at Dalton.”

Greenberg invited Epstein to the investment firm’s offices at 55 Water Street at the southern tip of Manhattan.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Terrence Malick’s Disciples: Why the auteur is the most influential director in Hollywood

Bilge Ebiri in The Yale Review:

In the winter of 2024, the photographer and filmmaker RaMell Ross released Nickel Boys, a masterful adaptation of a novel by Colson Whitehead. In a fragmentary, impressionistic style, the film portrays the friendship of two African American teens at a brutal Florida reform academy during the Jim Crow era. Acclaimed as a visionary movie, it ended up on many critics’ best-of-the-year lists and earned an Oscar nomination for Best Picture.

Ross is a fiercely independent artist. His first film, the lyrical 2018 documentary Hale County This Morning, This Evening, was also nominated for an Oscar. Afterward, he refused Hollywood’s overtures for years. So why did he take a meeting with the producers who reached out to him about making a studio-financed, big-budget adaptation of Nickel Boys? Ross’s explanation was simple: because one of them had produced Terrence Malick’s 2011 film, The Tree of Life. Ross’s reverence for Malick is plain in his films, which, like Malick’s, rely on extended montages of the everyday and do away with the conventional rules of cinematic storytelling, hovering instead between distant, melancholy reverie and hyperfocused, lived-in specificity. And he is not the only recent filmmaker who has fallen under Malick’s spell. Indeed, Malick’s sensibility, visual style, and working methods have had a profound influence on some of today’s best and most interesting directors.

Take Chloé Zhao, the director of the Oscar-winning Nomadland (2020). Her early films, all set in the American heartland, were regularly compared to Malick’s, and she herself pointed to The Tree of Life and Malick’s 2005 film, The New World, as influences on her 2021 Marvel superhero movie, Eternals. Those overtones persist in her latest, Hamnet, a film about the death of William Shakespeare’s only son and his subsequent creation of Hamlet. The movie may take place in Elizabethan England, but it is replete with lyrical passages and visions of nature that recall Malick’s work.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Turning Point: How the GOP consensus on Israel cracked

Andrew Cockburn in Harper’s Magazine:

On a cool evening in October, six weeks after Charlie Kirk was assassinated in full view of thousands at Utah Valley University, I joined a sea of young people lining up outside the auditorium on Indiana University’s sprawling Bloomington campus for an event sponsored by Kirk’s organization, Turning Point USA. Kirk himself had been scheduled to headline the event, one stop on a planned tour of colleges across the country. Instead we would hear from Tucker Carlson, once the star of Fox News and now a wildly popular podcast host. The choice was a pointed one given Carlson’s willingness to buck Republican orthodoxy, particularly on matters of foreign policy. He has vehemently denounced American military involvement abroad, including attacks on Iran, support for Ukraine, and most controversially, the U.S.-backed war in Gaza.

The political and religious cast of the crowd in Bloomington was signaled by the street vendors, who were doing brisk business offering red, white, and black make america great again hats, along with caps proclaiming jesus won and sweatshirts emblazoned with freedom and Kirk’s signature. In the center of the plaza outside the venue, hand-lettered signs proclaimed christian values? israel massacres innocents and would jesus ignore this? will youPointing to the signs, I asked Dane, a young self-described Christian who declined to give his last name, whether he agreed with their message. “We’ve heard for a few years how the left feels about it,” he told me. “But you’re starting to see a little bit of a change in the right. They’ve spent many, many years trying to get a common consensus belief that Israel is one of our very best allies, and that belief is starting to change. It’s not just a niche thing anymore. I would be quite concerned if I was a politician.”

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

2025: The Year of Demented Painting

Rachel Wetzler at Artforum:

If nothing else, 2025 was a good year for demented painting. This might have been obvious to anyone who saw Laura Owens’s maximalist fantasia at Matthew Marks in Chelsea this past spring—the single best gallery show I saw all year. The works on view deployed all manner of painterly illusion, trick, and gag. Giant canvases hung in the main space, their collage-like compositions built up from dense aggregates of silk-screened layers (over a hundred in some cases). These were set against artist-made wallpaper, with a trompe l’oeil border of pretzels, donuts, and assorted other confections dangling from electrical cords whose dainty loops were modeled after trailing vines. Hidden behind a false door was a wraparound installation of paintings on aluminum panel configured as a mural, featuring a grab bag of floriated patterns jostling and colliding, with miniature canvases intermittently popping out of trapdoors like cuckoo clocks. Throughout this madcap ensemble, Owens made liberal use of flatly painted drop shadows that introduced a confounding fictive depth, alongside exaggerated instances of real depth—fluffy pastel dollops and smears of paint with the consistency of buttercream projecting off the surface. At room-size scale, the combination was as destabilizing as it was ridiculous.

more here.

Enjoying the content on 3QD? Help keep us going by donating now.

Mandeville: Philosopher Of Pride

Andrea Branchi at Aeon Magazine:

In 1714, and in an enlarged edition in 1723, Mandeville published the prose volume that made him infamous: The Fable of the Bees: Or, Private Vices, Public Benefits. The original poem was reprinted with a series of commentary essays in which Mandeville expanded upon his provocative arguments that human beings are self-interested, governed by their passions rather than their reason, and he offered an explanation of the origin of morality based solely on human sensitivity to praise and fear of shame through a rhapsody of social vignettes. Mandeville confronted his contemporaries with the disturbing fact that passions and habits commonly denounced as vices actually generate the welfare of a society.

The idea that self-interested individuals, driven by their own desires, act independently to realise goods and institutions made The Fable of the Bees one of the chief literary sources of the laissez-faire doctrine. It is central to the economic concept of the market. In 1966, the free-market evangelist Friedrich von Hayek offered an enthusiastic reading of Mandeville that anointed the poet as an early theorist of the harmony of interests in a free market economy, a scheme that Hayek claimed was later expanded on by Adam Smith, reworking Mandeville’s paradox of ‘private vices, public benefits’ into the profoundly influential metaphor of the invisible hand. Today, Mandeville is standardly thought of as an economic thinker.

more here.

Enjoying the content on 3QD? Help keep us going by donating now.

Tuesday Poem

It Was Beginning Winter

It was beginning winter,
An in-between time,
The landscape still partly brown:
The bones of weeds kept swinging in the wind,
Above the blue snow.

It was beginning winter,
The light moved slowly over the frozen field,
Over the dry seed-crowns,
The beautiful surviving bones
Swinging in the wind.

Light traveled over the wide field;
Stayed.
The weeds stopped swinging.
The mind moved, not alone,
Through the clear air, in the silence.

Was it light?
Was it light within?
Was it light within light?
Stillness becoming alive,
Yet still?

A lively understandable spirit
Once entertained you.
It will come again.
Be still.
Wait.

by Theodore Roethke

Enjoying the content on 3QD? Help keep us going by donating now.

Monday, December 22, 2025

A threnody for the dictionary

Joseph Epstein at Commentary:

How many times during the past month have you gone to the dictionary, or if not the dictionary then to your computer, to look up a word? I go to mine with some frequency. Here are some of the words within recent weeks I’ve felt the need to look up: “algolagnia,” “orthoepist,” “cromulent,” “himation,” “cosplaying,” and “collocation.” The last word I half-sensed I knew but was less than certain about. I also looked up “despise” and “loath,” to be sure about the difference, if any, between them, and then had to check the difference between the latter when it has an “e” at its end and when it doesn’t. Over the years I must have looked up the word “fiduciary” at least half a dozen times, though I have never used it in print or conversation. I hope to look it up at least six more times before departing the planet. Working with words, it seems, is never done.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.