by Brooks Riley
Not long ago, having steeled myself for the read-through of yet another dry but informative assessment of the body’s immune response to Covid 19 and her variant offspring, I was pleasantly surprised to find myself being dragged into a barbaric tale of murder and mayhem, full of gory details and dire strategies.
This was not a thriller, or the reenactment of a famous battle, but rather as entertaining an article about Covid 19 as one could hope to find in these dark days, couched in the rhetoric of anthropomorphism. Katherine J. Wu, a staff writer at The Atlantic, as part of her ongoing coverage of the pandemic, casts the lowly T-cell in the role of ruthless mercenary on a murderous rampage through the body on behalf of the immune system, investing him (her, they or it?) with intent to kill all viral interlopers, which is exactly what a T-cell should be doing.
Just listen to this: When these immunological assassins happen upon a cell that’s been hijacked by a virus, their first instinct is to butcher. The killer T punches holes in the compromised cell and pumps in toxins to destroy it from the inside out. The cell shrinks and collapses; its perforated surface erupts in bubbles and boils, which slough away until little is left but fragmentary mush. The cell dies spectacularly, horrifically—but so, too, do the virus particles inside, and the killer T moves on, eager to murder again.
Has science writing ever produced such a graphic description of a biological killing spree? Conversely, what crime writer would endow his heroes with such unflinching maleficent intent? It’s a stunning piece of writing, but it also serves a hidden purpose: The reader will not forget this diabolical sequence—or the functions of a T-cell. How a T-cell attacks a virus will burn forever in the imagination, along with other memorable entertainments. Read more »