Seth Harp in Harper’s Magazine:
After the midair collision in January over the Potomac River between an Army helicopter and a regional jet packed with young figure skaters and their parents flying out of Wichita, Kansas, and considering the ongoing travails of the Boeing Company, which saw at least five of its airplanes crash last year, I was so concerned about the state of U.S. aviation that, when called on by this magazine to attend President Donald Trump’s military parade in Washington, on June 14, 2025, I decided to drive all the way from my home in Austin, Texas, even though it cost me two days behind the wheel and a gas bill as expensive as a plane ticket.
I was no less concerned about the prospect of standing on the National Mall on the day of the parade, a celebration of the two-hundred-fiftieth anniversary of the founding of the U.S. Army, which happened to coincide with Trump’s seventy-ninth birthday. The forecast predicted appropriately foul weather for the occasion, and there would be a number of helicopters, of both modern and Vietnam-era vintage, flying over the parade grounds. The Army’s recent track record didn’t bode well for those positioned under the flight path. In the past two years, there had been at least twenty-four serious accidents involving helicopters and nineteen fatalities, culminating with the collision over the Potomac, the deadliest incident in American commercial aviation since 2001.
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According to the philosopher Peter Sloterdijk, the 20th century’s form of life also began with the air. Sloterdijk puts the moment at 6 p.m. on April 22, 1915, near Ypres, when a German regiment under the command of Col. Max Peterson unleashed chlorine gas in warfare for the first time. Previously, violence in war had been directed at the human body; this attack targeted the “living organism’s immersion in a breathable milieu,” as Sloterdijk writes in “
The drug discovery and development landscape is plagued by inefficiency, risk and astronomical cost. Clinical success rates languish below 10%, convoluted in- and out-licensing workflows erode precious patent life, and industry estimates suggest that biopharma companies write off some $15 billion every year on deprioritized candidates. At the same time, more than 90% of oncology drugs—and a significant proportion of all therapeutics—will lose patent exclusivity within the next five years, creating a looming innovation shortfall. Partex is here to bridge that gap. As the world’s largest artificial intelligence (AI)-driven drug-asset manager, Partex supercharges pipelines, resurrects shelved compounds and slashes development time to clinic—revolutionizing discovery and development at every step.
Open one of the drawers in a collections cabinet at the United States Holocaust Memorial Museum, and you’ll find a small booklet of Efka cigarette papers. The papers are part of a broader story the museum tells about Nazism, corporate collaboration, and wartime propaganda.
Italy is not always the salvation of English-speaking people—but it does often seem that way. In film, in literature, in food, it’s the place where you go to find yourself. The real you, the one whose blazing depths have been obscured by the cold crust of convention. In The Enchanted April—the 1922 bestseller that turned Positano into a tourist destination—Elizabeth von Arnim suggested that the Mediterranean climate could burn off the impurities of the English soul, as if by a kind of Italian alchemy. English travelers from Byron to E. M. Forster advanced a similar sort of travel magic as a means for getting in touch with one’s soul. Keats, wracked with tuberculosis, went to Italy hoping to save his life.
Super Agers, by clinician Eric Topol, has just been published, but it was almost surreal for me as a US scientist to read the book now, with its optimistic take on the state of the medical field. Despite their extreme promise, many of the lines of research that Topol describes have been subject to
I meet a lot of people who don’t like their jobs, and when I ask them what they’d rather do instead, about 75% say something like, “Oh, I dunno, I’d really love to run a little coffee shop.” If I’m feeling mischievous that day, I ask them one question: “Where would you get the coffee beans?”
Here’s a test for infants: Show them a glass of water on a desk. Hide it behind a wooden board. Now move the board toward the glass. If the board keeps going past the glass, as if it weren’t there, are they surprised? Many 6-month-olds are, and by a year, almost all children have an intuitive notion of an object’s permanence, learned through observation. Now some artificial intelligence models do too.
According to the existential-risk researcher Luke Kemp, globalization has produced a planetary “
In a prescient essay published in 2000, the Princeton historian Robert Darnton – one of the grandees of the historical profession – proposed a new kind of history, one prompted as much by recent developments in Silicon Valley as anything gleaned in the archives. He called for ‘a general attack on the problem of how societies made sense of events and transmitted information about them, something that might be called the history of communication’. This, he argued, had to be much larger than just a history of newspapers. It had to encompass how information spread by word of mouth, the places where people convened to trade it and the multiple professions engaged in its dispersal.
The thesis of Peter Brannen’s new book is right there on the cover: “The Story of CO2 Is the Story of Everything.” But surely there’s no way he means everything, right?