The First Cell, Part 4: Giant Cells: “I am large, I contain multitudes”
The First Cell, Part 3: Force Majeure — Oncologists are as desperate as their patients
by Azra Raza All of the articles in this series can be found here. Everyone agrees that early cancer detection saves lives. Yet, practically everyone is busy studying end-stage cancer. Reviewing the history of carcinogenesis from 1911 on, I become unspeakably, depressed. Demoralized. For fifty years, massive intellectual and financial resources have been invested pursuing…
The First Cell, Part 2: Transposed Heads
by Azra Raza All of the articles in this series can be found here. Ninety percent cancers diagnosed at Stage I are cured. Ninety percent diagnosed at Stage IV are not. Early detection saves lives. Unfortunately, more than a third of the patients already have advanced disease at diagnosis. Most die. We can, and must,…
The First Cell, Part 1: Old yet a New Cancer Model
by Azra Raza All of the articles in this series can be found here. Cancer has occupied my intellectual and professional life for half a century now. Despite all the heartfelt investments in trying to find better solutions, I am still treating acute myeloid leukemia patients with the same two drugs I was using in…
Celebrating the Women of Pakistan
Editor’s Note: My sister Azra has kindly given us permission to publish remarks that she delivered to The Citizen’s Foundation gala in Houston a few days ago. She will provide translations of the Urdu poetry soon. by Azra Raza Thank you Dr. Abdullah Jafari, thank you TCF, thank you Houston for giving me this opportunity…
Mr. Wrong: Ifti Nasim (1946 – 2011)
The Nobleness of Life is to do Thus
The Nobleness of Life is to do Thus
Rx: Emily Post and Laura Claridge: Two Women Possessing the Genius of Etiquette
Azra Raza reviews Emily Post: Daughter of the Gilded Age, Mistress of American Manners by Laura Claridge Laura Claridge’s enormously enjoyable, carefully researched, exhaustively annotated, insightful and engaging biography Emily Post: Daughter of the Gilded Age, Mistress of Manners, made two points very clear to me; first, from birth to death, we humans need constant…
Qurratulain Hyder (Aini Apa), 1927-2007
Rx: Stephen Wolfram’s New Kind of Science
For Mother’s Day in May 2002, my husband Harvey ordered Stephen Wolfram’s book A New Kind Of Science for me. Harvey died a few days later and the book arrived after his memorial service. That summer I read the 1200-plus pages of this self-published tome, and I felt grateful to Mr. Wolfram as the book…
Rx: Ian McEwan, medical ethics and plagiarism
I recently read the novel Saturday by Ian McEwan. I have to admit that in the proverbial sense, despite all the excellent reviews this book has received since its release last year, it really is very good. Near the end, Mr. McEwan’s plot started me thinking about issues related to medical ethics, patient-doctor relationships and…
Rx: Harvey David Preisler
The Moving Finger writes; and, having writ,Moves on: nor all your Piety nor WitShall lure it back to cancel half a line,Nor all your Tears wash out a Word of it. —Omar Khayyam Harvey died on May 19th 2002, at 3:20 p.m. The cause of death was chronic lymphocytic leukemia/lymphoma. Death approached Harvey twice: once…
Rx: Thalidomide and Cancer
Rock Brynner, 54, historian, writer, former road manager for The Band and for Bob Dylan and son of the late actor Yul Brynner, knows both sides of the story of the drug thalidomide. In 1998, after suffering for five years from a rare immune disorder, pyoderma gangrenosum, Rock Brynner took thalidomide and went into remission.…
Rx: Germs are Us
In a peculiar sense, it is okay to refer to our individual selves as “we” without belonging to royalty, yet be scientifically precise since our bodies which have a thousand billion cells harbor ten thousand billion bacteria. Germs are Us. The male of our species may find it particularly hard to accept the idea that…
Rx: Sand piles and Cancer
In 2001, I read Mark Buchanan’s wonderful book “Ubiquity” and became introduced to the concept of “critical states universality” through the “sand pile” game devised by physicists Per Bak, Chao Tang and Kurt Weisenfeld. They created a computer game in which grains of sand fall slowly and in a single file, and as the pile…
Rx: Reductionist vs. pluralist views of Cancer
Cancer, the malignant evil that corrodes fatally, is supposed to start in one cell. In appearance and behavior, this cell and its daughters are so different from their “normal” predecessors and counterparts that they appear to represent a new species. In this essay, I suggest that the transformation of a non-malignant cell into a frankly…
Rx: SPICING CANCER TREATMENT
The population of India is now over a billion with an estimated 1.5 million cases of cancer diagnosed per year. The population of the United States is 295 million, and yet 1.5 million cancers will be diagnosed this year. The accompanying Table shows that the incidence of breast cancer in the US is 660/million while…