by Syed Tasnim Raza
This is a response to the article “A Cardiac Conundrum” by Alice Park in the March-April 2013 issue of Harvard Magazine. The article mostly discusses a new book: Broken Hearts: The Tangled History of Cardiac Care by David S. Jones, which I have not read, so the following comments are only in response to the article itself, which may or may not represent the book exactly. I am a heart surgeon and I will limit my comments to the parts of the article referring to coronary artery bypass graft operations, not to angioplasties.
The author indicts coronary artery bypass operations, which are performed widely by claiming that they “provided little or no improvement in survival rates over standard medical and lifestyle treatment except in the very sickest patients.”
Let me start by giving a little historical perspective, slightly different then the author's recalling. Until 1896, surgeons were too afraid to even attempt suture of the heart. In that year Ludwig Rehn of Frankfurt repaired a stab wound to the heart of a young man, who survived, thus beginning the era of heart surgery. From then until the 1950's most attempts at heart operations were largely unsuccessful. It is only after the development of the Heart-Lung machine (John Gibbon 1952) and it's further improvement at the University of Minnesota and the Mayo Clinic, between 1955 and 1960, that the modern era of heart surgery began. Coronary Artery Disease (CAD), which is blockage of coronary arteries by atherosclerotic plaques and can result in a heart attack was recognized mostly by indirect methods or post-mortem, until 1958, when selective coronary angiography was developed at the Cleveland Clinic. Before then it was the symptoms of CAD namely angina which was clinically recognized and attempts at surgical treatment for angina had been made since 1930's including denervation of the heart, surgically causing inflammation of the membrane surrounding the heart (pericardium), hoping that it would result in formation of new blood vessels (Beck's operation) and in 1960's implantation of Internal mammary artery into the muscle of the left ventricle with the hopes that new blood vessels would form (Vineburg operation). All these operations were unsuccessful and are of historical interest only. It was only after selective coronary angiography was possible in 1958, that Favalaro developed the operation that is now referred to as coronary artery bypass graft (CABG, pronounced cabbage) surgery. The first successful operation was performed in late 1967. The results of this operation were such a vast improvement over any other treatment then available that it was taken up by surgeons everywhere and by early 1990's over half a million such operations were being performed annually throughout the United States.