Being Friends with Oliver Sacks

Lawrence Weschler at The Believer:

I had just turned twenty-nine and he was forty-eight when we first met out there on City Island, but I quickly realized that he would make a wonderful subject for one of those multi-part profiles the magazine was famous for in those days, and across the next four years, I took on the role of a sort of beanpole Sancho to his capacious Quixote, traipsing about with him on his various rounds and travels, chronicling his in those days floridly neurotic ramblings, indeed, filling up over fifteen notebooks full of them, interviewing his friends and patients and earlier associates, and off to the side, trying to help him through that epic blockage, which, curiously, took the form of graphomania: he’d generated millions of words, just not the right ones, and, for his editors and me, most of the at times Sisyphean work consisted in pruning the damn thing back and then preventing him from mischiefing it yet further.

In addition, much of our growing friendship involved his trying to scandalize me with the horrible blight, as he saw it, of the fact that he was a (deeply closeted) homosexual. Actually, in fact, he had been celibate at that point for almost fifteen years (following a brief and vivid drug-fueled flowering during his medical residencies in California back in the early sixties) and would continue to be so for another twenty. 

more here.



The Radical Transformations of a Battered Women’s Shelter

Larissa MacFarquhar at The New Yorker:

In the years before Transition House existed, violence at home was considered a private matter between husband and wife. In the early sixties, Janet, an undergraduate at a Seven Sisters college, had just married Jonathan, who was in law school. (Both names are pseudonyms.) Jonathan had started beating her up almost daily; each time, he was filled with remorse, but he blamed Janet for provoking him. Janet had not known any violence growing up, so she found the situation disturbing and bizarre and kept it a secret from most people she knew. She explained her black eyes with the usual stories about bumping into things.

She and Jonathan went to see a therapist, who recommended individual treatment for each of them. Janet’s therapist asked her about her childhood and concluded that she was a moral ascetic with a rigid superego, but, in what she recognized as an undisciplined moment for a Freudian, he suggested that she might leave her husband.

more here.

On the Death of My Dear Friend, Agnes Heller

Andrew Arato at Public Seminar:

We have been friends, Ági and I, since 1969. I was much younger than she, having been born in the last year of the War in 1944. For a moment perhaps, we might have been, my mother and I, and Ági, in one of the same houses of the international ghetto, under Swedish, Swiss or Vatican weak protection. She was 14 or 15 back then, and her dramatic survival — by jumping into the Danube in front of an Arrow Cross Firing squad — has been often recounted. One bronze pair of shoes now on the shore could have been hers for all we know, although in this case they would stand for a survivor not a victim. Ági was an amazing survivor. She survived not only the Nazis, the Stalinists, the retributions after 1956, the Kadar regime and its sanctions, but also the New School’s firing in 1993 of her husband, Ferenc Fehér, a very brilliant man and a great friend of mine. Feri died one year after in Budapest, for no apparent physical cause. Ági, however, lived and stayed at the New School for many more years with the help of Judith Friedlander who became Dean. Undoubtedly, she would have also survived the Orbán era, but for the tragic, entirely non-political accident that took her life.

more here.

How a British royal’s monumental errors made India’s partition more painful

Adil Najam in The Conversation:

The bloodbath of partition also left the two nations that were borne out of it – India and Pakistan – deeply scarred by anguish, angst, alienation and animus.

By 1947, the political, social, societal and religious complexities of the Indian subcontinent may have made partition inevitable, but the murderous mayhem that ensued was not.

As a South Asian whose life was affected directly by partition, and as a scholar, it is evident to me that the one man whose job it was, above all else, to avoid the mayhem, ended up inflaming the conditions that made partition the horror it became.

That man was Lord Louis Mountbatten, the last Viceroy of British India.

How did Mountbatten contribute to the legacy of hatred that, 72 years later, still informs the bitter relationship between India and Pakistan?

More here.

Wednesday Poem

Waves

True little waves, from high above in a window seat
so few of you have enough of yourselves
to fold over onto, forming a dress

you wear out instantly, the most part
of you is continuous skin with its own living
texture curving over the bottom, a bone, though often enough

on land it appears you’re falling
all over yourselves to be tallest, each of you
prim threat of drowning should I contemplate

a swim, the window seat is just a way of taking in
the danger all at once, breathing the ultimatum in
and trying to breathe it back out at decent intervals.

by Jana Prikryl
from
No Matter
Penguin Books, 2019

What Toni Morrison Knew About Trump

Syreeta McFadden in The Atlantic:

I think a lot about Toni Morrison’s 1993 Nobel Prize lecture. Morrison, who died last week at the age of 88, was one of the nation’s most revered novelists and thinkers, and has left behind an immense opus that has generated renewed interest. Her acceptance speech serves as a prescient reference to the fact that journalists and political leaders today are wrestling with the language necessary to describe the social and political chaos ignited by the Trump administration. It also doubled as a rebuke to detractors flummoxed that Morrison, who wrote inimitable novels about African American life, was being honored with the highest literary prize in the world. In her talk, she invited the audience to engage in an imaginative thought-game, offering a parable of an old blind woman confronted by petulant children. Her speech, though literary and political in nature, outlines the function of language beyond the boundaries of academia and politics.

The parable begins as such: A group of kids sets out to visit an elderly wise woman, a purported oracle who lives at the edge of town, to prove her powers fraudulent. In Morrison’s retelling, this woman, an American descendant of enslaved black people, attracts these child visitors because “the intelligence of rural prophets is the source of much amusement.” One of the children demands of her: “Old woman, I hold in my hand a bird. Tell me whether it is living or dead.” The old woman, aware of their intent, does not answer, and after a beat she admonishes them for exploiting her blindness—the one difference between them. She tells them that she doesn’t know whether the bird is living or dead, but only that it is in their hands. “Her answer can be taken to mean: If it is dead, you have either found it that way or you have killed it. If it is alive, you can still kill it,” Morrison explained. “Whether it is to stay alive, it is your decision. Whatever the case, it is your responsibility.”

For Morrison, the “bird” was language, and she warned that everyone is culpable for the precarity of language in civil society. “When language dies, out of carelessness, disuse, indifference and absence of esteem, or killed by fiat,” she continued, “not only she herself, but all users and makers are accountable for its demise.” Through this address, Morrison slyly swiped at the national discourse at the time, which focused on how language should be used to define social, cultural, and political realities.

More here.

“Qutrit” Experiments Are a First in Quantum Teleportation

Daniel Garisto in Scientific American:

For the first time, researchers have teleported a qutrit, a tripartite unit of quantum information. The independent results from two teams are an important advance for the field of quantum teleportation, which has long been limited to qubits—units of quantum information akin to the binary “bits” used in classical computing. These proof-of-concept experiments demonstrate that qutrits, which can carry more information and have greater resistance to noise than qubits, may be used in future quantum networks. Chinese physicist Guang-Can Guo and his colleagues at the University of Science and Technology of China (USTC) reported their results in a preprint paper on April 28, although that work remains to be published in a peer-reviewed journal. On June 24 the other team, an international collaboration headed by Anton Zeilinger of the Austrian Academy of Sciences and Jian-Wei Pan of USTC, reported its results in a preprint paper that has been accepted for publication in Physical Review Letters. That close timing—as well as the significance of the result—has each team vying for credit and making critiques of the other’s work.

The name quantum teleportation brings to mind a technology out of Star Trek, where “transporters” can “beam” macroscale objects—even living humans—between far-distant points in space. Reality is less glamorous. In quantum teleportation, the states of two entangled particles are what is transported—for instance, the spin of an electron. Even when far apart, entangled particles share a mysterious connection; in the case of two entangled electrons, whatever happens to one’s spin influences that of the other, instantaneously. “Teleportation” also conjures visions of faster-than-light communication, but that picture is wrong, too. If Alice wants to send Bob a message via quantum teleportation, she has to accompany it with classical information transported via photons—at the speed of light but no faster. So what good is it?

More here.

Tuesday, August 13, 2019

Tuesday Poem

A Greeting on the Trail

Turning fifty, at last I come to understand,
belatedly, unexpectedly, and quite suddenly,
that poetry is not going to save anybody’s life,
least of all my own. Nonetheless I choose to believe
the journey is not a descent but a climb,
as when, in a forest of golden-green morning sunlight,
one sees another hiker on the trail, who calls out,
where are you bound, friend, to the valley or the mountaintop?
Many things—seaweed, pollen, attention—drift.
News of the universe’s origin infiltrates atom by atom
the oxygenated envelope of the atmosphere.
My sense of purpose vectors away on rash currents
like the buoys I find tossed on the beach after a storm,
cork bobbers torn from old crab traps.
And what befalls the woebegotten crabs,
caged and forgotten at the bottom of the sea?
Are the labors to which we are summoned by dreams
so different from the tasks to which the sunlight of reality
enslaves us? One tires of niceties. We sleep now
surrounded by books, books piled in heaps
by the bedside, stacked along the walls of the room.
Let dust accrue on their spines and colophons,
let their ragged towers rise and wobble.
Of course the Chinese poets were familiar with all this,
T’ao Ch’ien, Hsieh Ling-yün, Po Chü-i,
masterful sophisticates adopting common accents
for their nostalgic drinking songs and laments
to age and temple ruins, imperial avarice,
autumn leaves caught in a tumbling stream.
Read more »

The world of Bruno Schulz

Becca Rothfeld in The Nation:

The life of the Polish Jewish author Bruno Schulz was, by pedestrian measures, a small one. It ended prematurely in 1942, when he was murdered in the street at the age of 50 by a Gestapo officer, and it was almost entirely confined to his provincial hometown of Drohobycz. Schulz drew compulsively, and in his brooding sketches crammed big-headed figures into cramped frames and rooms with low, clutching ceilings. Schulz himself was short and hunched. In photographs, he glowers. “He was small, strange, chimerical, focused, intense, almost feverish,” a friend, the Polish novelist Witold Gombrowicz, recalled in a diary entry. His fiction, too, was small and strange. Schulz’s surviving output consists of just two collections of short fiction, some letters, a few essays, and a handful of stray stories. His longest work spans about 150 pages.

But these slim volumes have earned Schulz a soaring stature. In death, he has been enlarged beyond the bounds of his claustrophobic biography. He was beloved by John Updike, V.S. Pritchett, I.B. Singer, and Czesław Miłosz. He has been the subject of novelistic homages by Cynthia Ozick (The Messiah of Stockholm), Philip Roth (The Prague Orgy), and David Grossman (See Under: Love).

Long before his acolytes brought him back to life, however, Schulz was busy resurrecting himself.

More here.

As Elephants and Whales Disappear, They Take Valuable Cancer Clues With Them

Doug Johnson in Undark:

Compared to humans, whales and elephants can have hundreds of times the number of cells — and have similarly long natural lifespans — but their cells mutate, become cancerous, and kill them less frequently. This quirk of nature, which the ACE team is studying, is called Peto’s Paradox, named for Richard Peto, a British epidemiologist. In the late 1970s, he proposed that there must be some kind of natural selection for cancer suppression, because humans live longer and are much larger than mice, but the species have similar rates of the disease.

In 2011, ACE researchers, along with scientists at 11 other institutions worldwide, first started looking at how Peto’s Paradox manifests itself in the genomes of humpback whales by comparing the information in Salt’s genes to those of other cetaceans. According to the results reported this year, the parts of a whale’s genome that determine how and when a cell splits evolved quickly and coincided with when the animals grew to their enormous size. Marc Tollis — a biologist at Northern Arizona University’s School of Informatics, Computing, and Cyber Systems who joined and began leading the ACE study in 2015 — hopes that taking one of the amped up, cancer-fighting whale genes and putting it in the body of a smaller creature will help the latter fight off these cellular mutations: a mouse as a test, a human as a hopeful end result.

More here.

Our Caesar: Can the country come back from Trump?

Andrew Sullivan in New York Magazine:

Well, we now have a solid record of what Trump has said and done. And it fits few modern templates exactly. He is no Pinochet nor Hitler, no Nixon nor Clinton. His emergence as a cultish strongman in a constitutional democracy who believes he has Article 2 sanction to do “whatever I want” — as he boasted, just casually, last month — seems to have few precedents.

But zoom out a little more and one obvious and arguably apposite parallel exists: the Roman Republic, whose fate the Founding Fathers were extremely conscious of when they designed the U.S. Constitution. That tremendously successful republic began, like ours, by throwing off monarchy, and went on to last for the better part of 500 years. It practiced slavery as an integral and fast-growing part of its economy. It became embroiled in bitter and bloody civil wars, even as its territory kept expanding and its population took off. It won its own hot-and-cold war with its original nemesis, Carthage, bringing it into unexpected dominance over the entire Mediterranean as well as the whole Italian peninsula and Spain.

And the unprecedented wealth it acquired by essentially looting or taxing every city and territory it won and occupied soon created not just the first superpower but a superwealthy micro-elite — a one percent of its day — that used its money to control the political process and, over time, more to advance its own interests than the public good.

More here.

The Pleasures and Punishments of Long-Ass Films

Nick Pinkerton at The Baffler:

The current champion of heavyweight cinema, who vacillates between gallery and traditional cinematic presentation, must be the Chinese documentarian Wang Bing, who broke out internationally with his first film Tie Xi Qu: West of the Tracks (2003) and has subsequently produced the fourteen-hour Crude Oil (2008)—premiered as an installation at the 2008 International Film Festival Rotterdam—as well as the nearly nine-hour Dead Souls (2018). Andrew Chan, writing for Film Comment in 2016, distilled the role of duration in Wang’s work, writing, “Wang’s durational extremes do not just carry with them the weight of history and the inertia of the present; they also suggest that we as viewers might repay the gift of his subjects’ nakedness with our own sustained submission.” Chan is writing specifically about Wang’s 2013 ‘Til Madness Do Us Part, a nearly four-hour film that takes place almost entirely inside a dismal, crumbling mental institution doing double-duty as a lock-up for political undesirables. “Time in these films does not embrace, it provokes,” Chan continues, with further reference to West of the Tracks. “It’s felt as sacrifice and labor. And the aim is to make us earn, as if such a thing were possible, the right to lay eyes on humiliations that are at once collectively borne and unbearably private.”

more here.

The Literary Marmoset

Dustin Illingworth at The Paris Review:

Mitz: The Marmoset of Bloomsbury, by Sigrid Nunez

For all the High Modern sophistication of the writers who made up the Bloomsbury set in England in the early 1900s, there remains something creaturely about the collective. It is as if, beneath the frocks and tweeds, a simian itch lingered. To begin with, there were the names they gave one another, curious and whiskery terms of endearment: Virginia Woolf and her husband Leonard called each other Mandrill and Mongoose; Vanessa Bell referred to her sister as Singe (ape in French) or Goat, while Vanessa herself was known as Dolphin; Virginia’s friend and sometime lover Vita Sackville-West gave her the private name of Potto, a kind of lemur; and several members of the group referred to T. S. Eliot in private letters as Old Toad. The impulse would occasionally manifest in their art. Take, for instance, Flush: A Biography, Woolf’s imaginative consideration of the poet Elizabeth Barrett Browning’s cocker spaniel.

The fictions of Sigrid Nunez are often similarly attuned to animals, though they serve different ends here. They are not, as in Woolf, an uncharted tributary into the river of animal consciousness. Instead, they act as a conduit for the unpredictable weight of self-knowledge.

more here.

From Lahore to Lancashire

John Keay at Literary Review:

A Britain without the South Asian British is now almost unthinkable. With a few exceptions – farming, fishing and the armed forces spring to mind – there are few sectors of UK life where the descendants of South Asian immigrants are not prominent. Kavita Puri, for example, author of the harrowing Partition Voices, is a distinguished broadcaster whose father, Ravi, relocated from Delhi to Middlesbrough in 1959. The Puri family had lived originally in Lahore. But while the Puris were Hindu, the majority of Lahoris were Muslim. Under the terms of the 1947 partition plan, Lahore became part of Pakistan. The Puri family, in order to survive the carnage that ensued, had to flee across the border to the new Indian state, ending up in Delhi.

For Ravi, partition meant not one but multiple displacements, of which the move to Middlesbrough was just the last. To his daughter, it’s self-evident that ‘there is a link between partition and migration to Britain’, since it was those areas of India and Pakistan most affected by partition that became the major contributors to the flow of emigrants. But the chain of causation was not always so obvious. Of all the various South Asian communities in Britain today, the largest is that of Pakistanis from Punjab, who found work in the mill towns of Lancashire and Yorkshire in the 1960s.

more here.

The Promise and Price of Cellular Therapies

Siddhartha Mukherjee in The New Yorker:

It matters that the first patients were identical twins. Nancy and Barbara Lowry were six years old, dark-eyed and dark-haired, with eyebrow-skimming bangs. Sometime in the spring of 1960, Nancy fell ill. Her blood counts began to fall; her pediatricians noted that she was anemic. A biopsy revealed that she had a condition called aplastic anemia, a form of bone-marrow failure. The marrow produces blood cells, which need regular replenishing, and Nancy’s was rapidly shutting down. The origins of this illness are often mysterious, but in its typical form the spaces where young blood cells are supposed to be formed gradually fill up with globules of white fat. Barbara, just as mysteriously, was completely healthy. The Lowrys lived in Tacoma, a leafy, rain-slicked city near Seattle. At Seattle’s University of Washington hospital, where Nancy was being treated, the doctors had no clue what to do next. So they called a physician-scientist named E. Donnall Thomas, at the hospital in Cooperstown, New York, asking for help.

In the nineteen-fifties, Thomas had attempted a new kind of therapy, in which he infused a leukemia patient with marrow extracted from the patient’s healthy identical twin. There was fleeting evidence that the donated marrow cells had “engrafted” into the patient’s bones, but the patient had swiftly relapsed. Thomas had tried to refine the transplant protocol on dogs, with some marginal success. Now the Seattle doctors persuaded him to try again in humans. Nancy’s marrow was faltering, but no malignant cells were occupying it. Would the blood stem cells from one twin’s marrow “take” in the other twin? Thomas flew to Seattle. On August 12, 1960, Barbara was sedated, and her hips and legs were punctured fifty times with a large-bore needle to extract the crimson sludge of her bone marrow. The marrow, diluted in saline, was then dripped into Nancy’s bloodstream. The doctors waited. The cells homed their way into her bones and gradually started to produce normal blood. By the time she was discharged, her marrow had been almost completely reconstituted. Nancy emerged as a living chimera: her blood, in a sense, belonged to her twin.

More here.

Kary Mullis, Inventor of the PCR Technique, Dies

Kerry Grens in The Scientist:

Kary Mullis, whose invention of the polymerase chain reaction technique earned him the Nobel Prize in Chemistry in 1993, died of pneumonia on August 7, according to MyNewsLA.com. He was 74 years old. According to a 1998 profile in The Washington Post, Mullis was known as a “weird” figure in science and “flamboyant” philanderer who evangelized the use of LSD, denied the evidence for both global warming and HIV as a cause of AIDS, consulted for O.J. Simpson’s legal defense, and formed a company that sold jewelry embedded with celebrities’ DNA. The opening paragraph of his Nobel autobiography includes a scene depicting a visit from Mullis’s dying grandfather in “non-substantial form.” “He was personally and professionally one of the more iconic personalities science has ever witnessed,” Rich Robbins, the founder and CEO of Wareham Development, a real estate developer for a number of biotech companies, tells the Emeryville, California-based paper, the E’ville Eye.

Mullis was born in North Carolina in 1944 and earned a chemistry degree from Georgia Tech and a PhD in biochemistry from the University of California, Berkeley. In the early 1980s, when Mullis was working for the biotech company Cetus Corp in Emeryville, he developed the DNA replication technique polymerase chain reaction (PCR)—one of the most widely used methods in molecular biology. Writing in The Scientist in 2003, Mullis described his first attempt at PCR in 1983 as “a long-shot experiment. . . . so [at midnight] I poured myself a cold Becks into a prechilled 500 ml beaker from the isotope freezer for luck, and went home. I ran a gel the next afternoon [and] stained it with ethidium. It took several months to arrive at conditions [that] would produce a convincing result.” Both Science and Nature rejected the resulting manuscript, which was ultimately published in Methods in Enzymology in 1987.

More here.

Sunday, August 11, 2019

Burning Down the House

Alan Weisman in the New York Review of Books:

Climate scientists’ worst-case scenarios back in 2007, the first year the Northwest Passage became navigable without an icebreaker (today, you can book a cruise through it), have all been overtaken by the unforeseen acceleration of events. No one imagined that twelve years later the United Nations would report that we have just twelve years left to avert global catastrophe, which would involve cutting fossil-fuel use nearly by half. Since 2007, the UN now says, we’ve done everything wrong. New coal plants built since the 2015 Paris climate agreement have already doubled the equivalent coal-energy output of Russia and Japan, and 260 more are underway.

Environmental writers today have a twofold problem. First, how to overcome readers’ resistance to ever-worsening truths, especially when climate-change denial has turned into a political credo and a highly profitable industry with its own television network (in this country, at least; state-controlled networks in autocracies elsewhere, such as Cuba, Singapore, Iran, or Russia, amount to the same thing). Second, in view of the breathless pace of new discoveries, publishing can barely keep up. Refined models continually revise earlier predictions of how quickly ice will melt, how fast and high CO2 levels and seas will rise, how much methane will be belched from thawing permafrost, how fiercely storms will blow and fires will burn, how long imperiled species can hang on, and how soon fresh water will run out (even as they try to forecast flooding from excessive rainfall). There’s a real chance that an environmental book will be obsolete by its publication date.

More here.

The Physics of Dissent

Erica Chenoweth in Nature:

The recent revolutions in Algeria and Sudan remind us that bottom-up movements of people power can create sweeping political transformations. They did this in part by mobilizing huge numbers of active protestors—1 million in Algeria, and around 1 million in Sudan—which constituted impressive numbers in absolute terms. Yet due to coordination problems and the possibility of free riding—where those who stay on the side-lines can benefit from the results of mass mobilization without paying the costs or assuming the risk of participation—few mass movements have been able to mobilize significant proportions of their population. Algeria’s peak event during its “Smile Revolution” reportedly mobilized under 2.5% of the country’s population to effectively topple Bouteflika’s government in March 2019. And Sudan’s ongoing revolution, which reportedly mobilized fewer than 2.5% of Sudan’s national population, has already toppled the 30-year role of Omar al-Bashir and forced the transitional military council into a transitional power-sharing agreement with the opposition.

How do people power movements succeed while mobilizing modest proportions of the population? And how can dissidents successfully assess their power along the way? In our paper, we begin to answer these questions by turning to a simple metaphor: the physical law of momentum.

More here.