Kai Kupferschmidt in Science:
Edward Holmes does not like making predictions, but last year he hazarded a few. Again and again, people had asked Holmes, an expert on viral evolution at the University of Sydney, how he expected SARS-CoV-2 to change. In May 2020, 5 months into the pandemic, he started to include a slide with his best guesses in his talks. The virus would probably evolve to avoid at least some human immunity, he suggested. But it would likely make people less sick over time, he said, and there would be little change in its infectivity. In short, it sounded like evolution would not play a major role in the pandemic’s near future.
“A year on I’ve been proven pretty much wrong on all of it,” Holmes says.
Well, not all: SARS-CoV-2 did evolve to better avoid human antibodies. But it has also become a bit more virulent and a lot more infectious, causing more people to fall ill. That has had an enormous influence on the course of the pandemic.
More here.

Exactly one year ago, I did not die from poisoning by a chemical weapon, and it would seem that corruption played no small part in my survival. Having contaminated Russia’s state system, corruption has also contaminated the intelligence services. When a country’s senior management is preoccupied with protection rackets and extortion from businesses, the quality of covert operations inevitably suffers. A group of FSB agents applied the nerve agent to my underwear just as shoddily as they incompetently dogged my footsteps for three and a half years – in violation of all instructions from above – allowing
Deep learning, the artificial-intelligence technology that powers voice assistants, autonomous cars, and Go champions, relies on complicated “neural network” software arranged in layers. A deep-learning system can live on a single computer, but the biggest ones are spread over thousands of machines wired together into “clusters,” which sometimes live at large data centers, like those operated by Google. In a big cluster, as many as forty-eight pizza-box-size servers slide into a rack as tall as a person; these racks stand in rows, filling buildings the size of warehouses. The neural networks in such systems can tackle daunting problems, but they also face clear challenges. A network spread across a cluster is like a brain that’s been scattered around a room and wired together. Electrons move fast, but, even so, cross-chip communication is slow, and uses extravagant amounts of energy.
W
In the rat-infested trenches of France, Raymond Chandler became an alcoholic, and stayed one. In 1932, after booze had gotten him fired from a cushy job, he resolved to cut down on the gin and become a novelist. He began by selling hard-boiled detective yarns to the pulpy magazine Black Mask, then later sold his first novel, “The Big Sleep,” to Alfred A. Knopf. In 1943, Chandler’s third novel, “The High Window,” was read by the Paramount director Billy Wilder. He liked the way Chandler wrote dialogue, and offered him a contract of $750 a week for 10 weeks to work with him on a screenplay for “Double Indemnity,” James M. Cain’s novel. Chandler had never written for the screen, and didn’t like the idea of being subservient to a young Austrian-born Jew who had written dozens of screenplays in Berlin and Hollywood. But Chandler was broke, and had a sick wife to care for. He signed up.
Chris Lehmann in The New Republic:
THE UNITED STATES has forgotten the hobo. We recognize the problem of homelessness, but the rootless rambler who steals rides on freight trains seems a relic of a long gone past. Even the word itself, hobo, is outdated. The same goes for the word tramp, which, if used at all tends to be for slut-shaming purposes. The term bum remains, but it, too, is derogatory, perhaps only acceptable as a verb, as in, “Can I bum a smoke?”
Emilie Bickerton in the NLR’s Sidecar:
Kim Stanley Robinson in the FT:
T
When you go on a first date, do you struggle to make conversation? Read Morris Bishop’s
There is a parallel between Timothy Brennan’s biography of Edward Said and the latter’s most famous book. Like Orientalism in 1978, Places of Mind appears at a time when colonialism and race have once again become subjects of public debate in North America and Western Europe. Reviewers have linked the reception of Said’s book and the politics it enunciated to that facing the supporters of movements like Black Lives Matter or Rhodes Must Fall. And it was to find out how we might understand such a trajectory that I was eager to read the biography. Said was one of the earliest non-European immigrants to achieve fame in the American academy, and I wanted to know how he managed to spark the first new debate on imperialism there since its formal dissolution.