Philippe Lemoine at CSPI:
As many countries are going through another wave of infections, including some where the vast majority of the population has been vaccinated, many are starting to despair that we’ll ever see the end of the pandemic. In this post, I will argue that, on the contrary, not only is the pandemic already on its way out, but the virus will be relatively harmless after it has become endemic. This is going to happen not because the SARS-CoV-2 will become intrinsically less dangerous, although it might, but rather because what made the virus so dangerous was that nobody had immunity against it, so once it has become endemic it will infect fewer people and even those who end up infected will be much less at risk. Moreover, I will explain that, despite widespread anxiety about the emergence of new variants and the danger of immune evasion, the fact that SARS-CoV-2 is mutating will not prevent this outcome because of the way immunity works. Finally, I will argue that, although some people are calling to pursue the eradication of SARS-CoV-2 (as we have done with smallpox), we almost certainly couldn’t eradicate it even if we wanted to and that even if we could it wouldn’t be worth it.
More here.

Matter and energy are neither created nor destroyed, or so says modern physics. The subatomic substrate that adds up to the eyes scanning these words, the fingers holding them within sight and all the rest of your soft, unaccountable self, used to belong to other things—an apple or a cow, maybe—and they will belong to yet others in the future. What we are now, as long as we are, is a temporary contraction.
Researchers from MIT, the McGovern Institute for Brain Research at MIT, the Howard Hughes Medical Institute, and the Broad Institute of MIT and Harvard have developed a new way to deliver molecular therapies to cells. The system, called SEND, can be programmed to encapsulate and deliver different RNA cargoes. SEND harnesses natural proteins in the body that form virus-like particles and bind RNA, and it may provoke less of an immune response than other delivery approaches.
Mr. Close did not like to think of himself as a realist, photo or otherwise. In many ways he was closer to a conceptualist like Sol LeWitt, whose sculptures and murals were made according to preconceived rules and instructions. Tension between opposites like realism and abstraction, surface and depth, reality and illusion remained central to Mr. Close’s art throughout his career.
Whatever museums ultimately decide to do about Mr. Close, some say they can no longer afford to simply present art without addressing the issues that surround the artist — that institutions must play a more active role in educating the public about the human beings behind the work.
Something is amiss with democracy. Ask people from any or no political persuasion and they’re likely to give a similar story: contemporary politics has gone haywire because one side (or both) has lost touch with reality. We are living in a ‘post-truth’ partisan news hellscape that prioritises ‘feelings over facts’ and disregards the natural authority of the truth. But all sides seem to agree that there is a ‘truth’ that explains what really makes someone a woman, or an institution racist, or a politician fascist, in a way that compels acceptance from those who otherwise disagree. What we need to do is further emphasise the importance of science and reason, and perhaps sanction the overtly partisan media outlets that mislead otherwise good-natured people, then everyone will come to their senses and agree on things because they are true, because they reflect reality. Humans are rational, remember? Surely,
Global greenhouse gas emissions must peak in the next four years, coal and gas-fired power plants must close in the next decade and lifestyle and behavioural changes will be needed to avoid climate breakdown, according to the
Ed Miliband, now freed from the burden of party leadership, has at last resolved the tension between centrist caution and radical ambition firmly in favor of the radical option. In his funny and self-deprecating new book, GO BIG: How To Fix Our World, Miliband makes the case that the only way forward now for center-left parties is to embrace a radical platform of institutional innovation. The book is therefore addressed not only to a British audience, but to parties and activists in the social democratic tradition elsewhere. It has strong resonances for those, such as partisans of the French Parti Socialiste or the German SPD, who face the dangerous prospect of their parties being beached by the tides of history. As its title suggests, GO BIG is a sustained argument for a level of political ambition that would cast the Labour Party’s Blairite era deep into the dustbin of history.
Ashura
The argument was this: America at its most distinctive wasn’t Judeo-Christian or capitalist or even democratic in a simple way. It was pagan. Not an earth spirit paganism of the moors and glens, but a polytheistic, commercial, cosmopolitan paganism of the bazaar and the agora. We invested objects, people, and performances with the power of our dreams and fears, and then we organized ourselves around those idols in “non-exclusive communities of desire,” arguing about them, buying and selling pieces and images of them on the open market, trying to woo others into our camp and score points over rival camps. We were a democratic people, but to see American democracy clearly was to understand that our democracy renewed itself on a substratum of pagan devotions to movie stars, rock stars, oil paintings, charismatic political figures, football teams, ingenues, mystery novels, muscle cars, runway shows, action movies, and action painters.
What is drag, anyway?
When I was about 6, my mind did something wondrous, although it felt perfectly natural at the time. When I encountered the name of any day of the week, I automatically associated it with a color or a pattern, always the same one, as if the word embodied the shade. Sunday was dark maroon, Wednesday a sunshiny golden yellow, and Friday a deep green. Saturday was interestingly different. That day evoked in my mind’s eye a pattern of shifting and overlapping circular forms in shades of silver and gray, like bubbles in a glass of sparkling water.
In explaining the rationale for approving female-libido drugs, the FDA often cites the “unmet medical need.” Yet researchers are fiercely divided over the question of just how many women lack libido and how best to help them. If you believe advertising for Vyleesi, American women suffer from an epidemic of insufficient horniness. More than 6 million premenopausal women — one in 10 — have low sexual desire, the website claims.
This new surge brings a jarring sense of déjà vu. America has fallen prey to many of the