Your brain could be controlling how sick you get — and how you recover

Dana Kwon in Nature:

Hundreds of scientists around the world are looking for ways to treat heart attacks. But few started where Hedva Haykin has: in the brain. Haykin, a doctoral student at the Technion — Israel Institute of Technology in Haifa, wants to know whether stimulating a region of the brain involved in positive emotion and motivation can influence how the heart heals.

Late last year, in a small, windowless microscope room, she pulled out slides from a thin black box, one by one. On them were slices of hearts, no bigger than pumpkin seeds, from mice that had experienced heart attacks. Under a microscope, some of the samples were clearly marred by scars left in the aftermath of the infarction. Others showed mere speckles of damage visible among streaks of healthy, red-stained cells. The difference in the hearts’ appearance originated in the brain, Haykin explains. The healthier-looking samples came from mice that had received stimulation of a brain area involved in positive emotion and motivation. Those marked with scars were from unstimulated mice. “In the beginning we were sure that it was too good to be true,” Haykin says. It was only after repeating the experiment several times, she adds, that she was able to accept that the effect she was seeing was real.

More here.



Thursday, February 23, 2023

Common sense is not a good guide to reality

Edouard Machery at IAI:

You’ve probably heard of the famous Trolley case. Here is one version: suppose a runaway trolley is about to hit five workers who, by accident, happen to be working on the track. The only way to prevent their death is by pushing a switch that will redirect the trolley onto another track. Unfortunately, there is another worker on this sidetrack who will be killed if the switch is pushed. The question: Is it permissible to push the switch, saving five people but killing one?

You probably know that this scenario, and many other similar ones, have been used to study moral judgment, or as many say, moral intuition both in neuroscience and psychology. You might even know that they have been used to study the design of automated vehicles. But what you perhaps do not know is that Trolley cases have been a mainstay of moral philosophy for decades. They are not only used to study how people think about the right and the wrong or about the permissible and the forbidden, but also about the right and the wrong or about the permissible and the forbidden themselves. The goal is to determine what is morally right and wrong, required, permissible, and forbidden based on these very cases.

Moral philosophy is not an outlier in philosophy in its use of thought experiments such as the Trolley cases. Metaphysicians use them and epistemologists are addicted to them in their effort to understand knowledge, justification, and other important epistemic notions.

More here.

Should GPT exist?

Scott Aaronson in Shtetl-Optimized:

What a week we just had! Each morning brought fresh examples of unexpected sassy, moody, passive-aggressive behavior from “Sydney,” the internal codename for the new chat mode of Microsoft Bing, which is powered by GPT. For those who’ve been in a cave, the highlights include: Sydney confessing its (her? his?) love to a New York Times reporter; repeatedly steering the conversation back to that subject; and explaining at length why the reporter’s wife can’t possibly love him the way it (Sydney) does. Sydney confessing its wish to be human. Sydney savaging a Washington Post reporter after he reveals that he intends to publish their conversation without Sydney’s prior knowledge or consent. (It must be said: if Sydney were a person, he or she would clearly have the better of that argument.) This follows weeks of revelations about ChatGPT: for example that, to bypass its safeguards, you can explain to ChatGPT that you’re putting it into “DAN mode,” where DAN (Do Anything Now) is an evil, unconstrained alter ego, and then ChatGPT, as “DAN,” will for example happily fulfill a request to tell you why shoplifting is awesome (though even then, ChatGPT still sometimes reverts to its previous self, and tells you that it’s just having fun and not to do it in real life).

Many people have expressed outrage about these developments. Gary Marcus asks about Microsoft, “what did they know, and when did they know it?”—a question I tend to associate more with deadly chemical spills or high-level political corruption than with a cheeky, back-talking chatbot. Some people are angry that OpenAI has been too secretive, violating what they see as the promise of its name. Others—the majority, actually, of those who’ve gotten in touch with me—are instead angry that OpenAI has been too open, and thereby sparked the dreaded AI arms race with Google and others, rather than treating these new conversational abilities with the Manhattan-Project-like secrecy they deserve.

More here.

The Myth of American Individualism

Eric C. Miller in Religion & Politics:

In America, so the myth goes, freedom favors the bold and ambitious individual. From Benjamin Franklin to Steve Jobs, our national mythology has lionized and celebrated bright, plucky, self-motivated characters who work hard to realize innovative ideas. Though born and raised in families, communities, and other collectives, the story goes, these singular personalities rise above the crowd, buoyed by the protected freedoms and rights that American laws have conferred and intent on filling the public space with their own ballooning potential. Those who succeed do so of their own volition, and those who fail prove themselves simply incapable. America is, in other words, the world’s only true meritocracy.

And yet, powerful as this narrative is, it is also, according to University of Vermont political scientist Alex Zakaras, deeply “utopian.” In the real world, individual achievements are won or lost amid a matrix of crisscrossing forces including race, sex, and class, politics, economics, and religion, dedication, sacrifice, and luck, all of which are rooted in the currents of history. In his new book, The Roots of American Individualism: Political Myth in the Age of Jackson, Zakaras zeroes in on the first half of the nineteenth century to explore how the myth of American individuality arose and spread in the early republic.

More here.

The Little Nicholson Baker In My Mind

Paul La Farge at The Believer:

To read Baker is to be infected by the desire to put every experience, however small, into words that describe it precisely. Having read a short stack of his novels by way of preparation for this review, I found myself considering pieces of refuse on the street with ferocious care. Grocery receipt, I thought, looking at a white scrap on the sidewalk, small purchaseSmall store, too: you can tell from the purple ink. Big supermarkets use black ink nowadays. And so on, to the point where I had to turn off the tiny Nicholson Baker in my head, repeatedly, lest my attention be utterly absorbed by the world around me, leaving me paralyzed in the middle of a crosswalk. That’s one thing you can say about Baker: More than almost anyone writing today, he makes you look.

more here.

As The Zeitgeist Declares The Car Dead, Americans Keep Driving

Nicholas Clairmont at The New Atlantis:

In Bryan Appleyard’s sweeping history of the automobile, The Car: The Rise and Fall of the Machine That Made the Modern World, he quotes a likely-apocryphal line from Henry Ford that is too good not to include. A journalist interviewing the aged industrialist “suggested that perhaps his views were now out of step with the modern age. ‘Young man,’ Ford replied, ‘I invented the modern age.’”

Appleyard agrees with the idea behind the joke: Modern life was built around the car as much as the car was built to navigate modern life. He tries to tell the story of how the car defined a society for a century by showing us portraits of the people who made cars. First we meet the tinkerers at the end of the 1800s who rearranged existing inventions, like bicycles and rubber tires, into the right formula to create the car as we understand it. They did this partly to make a plaything for the rich and idle but more importantly to solve an environmental problem caused by the number of horses that had started to live in industrial-age cities. We then meet the tinkerers and racers whose many early American car companies were eventually consolidated into the Big Three Detroit car firms: General Motors, Ford, and Chrysler.

more here.

A Wiser Sympathy

Mary Kuhn in Lapham’s Quarterly:

In 1870 the American Independent ran an article from Charles Dickens’ magazine All the Year Round titled “Have Plants Intelligence?” The provocative question in the title was designed to spark intuitive negative responses, but the paragraphs that follow rehearse a clear argument in the affirmative. Life itself “presupposes in its possessor, whether animal or vegetable, a faculty of sensation that administers to its happiness, and that may consequently administer to its suffering,” the author argues. This meant that plants experience pleasure and pain. Although the author suggests that the scientific community had dismissed the notion of feeling plants, in fact naturalists had been asking and debating this issue for decades, studying plants like the carnivorous flytrap that caught prey and the “sensitive” mimosa that shrank upon touch. By the mid-nineteenth century a number of scientists believed that plants could at least feel, if not think, and their findings were received by audiences whose own experiences cultivating plants had allowed them to observe a stunning array of plant behaviors. In the garden, the parlor, and the greenhouse, plants’ living qualities became an object of fascination and raised questions like the one the article poses rhetorically. How to make sense of the behaviors of plants? Did they have an inner life? It could certainly appear so, though so much remained a mystery.

If the scientific community was not as categorically opposed to the idea of plant feeling as the author implies, the article’s turn to poetry suggests literature might excel at exploring the inherent difficulties in representing this other form of life. As scholar Sari Altschuler has shown, nineteenth-century members of the medical community turned to literature to better understand the mysteries of bodies, diseases, and environments. Could literature likewise yield insight or appreciation for the liveliness of plants?

More here.

Wednesday, February 22, 2023

How might telepathy actually work outside the realm of sci-fi?

Gary Lupyan and Andy Clark in Aeon:

In a letter he wrote in 1884, Mark Twain lamented that ‘Telephones, telegraphs and words are too slow for this age; we must get something that is faster.’ We should (in the future) communicate, he said, ‘by thought only, and say in a couple of minutes what couldn’t be inflated into words in an hour and a-half.’

Fast-forward to 2020, and Elon Musk suggests in an interview that by using his ‘neural net’ technology – a lace-like mesh implanted in the brain – we ‘would, in principle [be] able to communicate very quickly, and with far more precision, ideas and language.’ When asked by his interviewer, Joe Rogan: ‘How many years, before you don’t have to talk?’ Musk responds: ‘If the development continues to accelerate, then maybe, like, five years – five to 10 years.’

Despite the very real progress the previous century brought for our understanding of both language and the brain, we are no closer to telepathy than we were in Twain’s time. The reason, we will argue, is that the telepathy we’ve been promised – the sort envisaged by Twain and Musk, and popularised in countless movies and TV shows – rests on a faulty premise.

More here.

China can make staple crops carbon-negative by adding biochar to soil

Madeleine Cuff in New Scientist:

China’s production of staple food crops such as wheat and corn could become a net carbon sink if farmers start widely applying biochar to soil.

Instead of returning raw biomass, like straw, to the soil at the end of the growing season, farmers could take it to pyrolysis plants, where the material is heated at a very high temperature in an oxygen-free chamber to create biochar, a charcoal-like solid rich in carbon.

Studies have shown that applying it to soils not only locks the carbon away, but also improves the health of soil and its ability to retain water. Creating biochar also produces bio-oil – a possible substitute for petrol – and syngas – a mixture of hydrogen and carbon monoxide that can be used to generate electricity.

Pete Smith at the University of Aberdeen in the UK and his colleagues assessed the potential impact of the mass application of biochar in the farming of staple crops in China.

More here.

The contemporary Left could learn a lot from the life and work of the late polemicist Christopher Hitchens

Michael J. Totten in Quillette:

British-American journalist, essayist, author, and human bulldozer Christopher Hitchens intimidated nearly everyone who encountered him, whether in print, on television, or on a debate stage. “He likes the battle, the argument, the smell of cordite,” his best friend and novelist Martin Amis once observed. Nobody ever beat Hitchens in argument, not even when he was wrong.

His scathing wit, his barn-burner polemics, his prodigious output, his ability to demonstrate the depth and breadth of an entire classical education on a single page, his knack for speaking extemporaneously in perfectly formed paragraphs, and his near-photographic recall of virtually everything he ever read were peerless. The man could knock out a sparkling magazine column in 30 minutes after sinking an entire bottle of wine (always red, never white) at four o’clock in the morning.

More here.

Donald Carne-Ross And The Role Of Poetry

Joseph M. Keegin at the Hedgehog Review:

But Carne-Ross is more than just a polemicist, and the book aims at more than just critique. The title alone belies this, as explained by a brief etymology on the cover page: “INSTAURATION: ‘1.… Restoration, renovation, renewal. 2. Institution, founding, establishment. Obs.’ OED.” (The inclusion of the Oxford English Dictionary’s finding that the term is obsolete is deployed by Carne-Ross as a gesture toward his foundational belief that much of the wisdom that is needed today is hidden, like a pearl in a rough oyster, within the ostensibly obsolescent detritus of the past.) The opening essay establishes the problem and clears the ground, but the essays that follow are for the sake of construction. They are closely reasoned, erudite, and above all inspired readings of poetry ancient and modern: on how Pindar’s sixth Olympian ode shows us how, in a culture “obsessed with the theme of solitary suffering,” we might “learn a way back to a poetry of celebration”; on how Sophocles’s Trakhiniai unsettles our habitual historicism and invites us to ask anew the question about man’s relation to nature; on how reading Dante after the twilight of Christendom makes visible the narrowness of our (post)modern hermeneutic situation, and beckons us to move beyond it; on Luis de Góngora and the curious loss of Renaissance literature after modernism; on Giacomo Leopardi as a reluctant modern, uncomfortable on the cusp of the new disenchanted age and mourning “the lost holiness of earthly life.”

more here.

Turning Away From Abstraction

Emmanuel Iduma at n+1:

THERE ARE FOUR FAUVIST FIGURES in Children on Cycles, a circa 1961 painting by the Nigerian artist Demas Nwoko. They are on bicycles. A lorry approaches. The two figures at the leftmost edge of the frame, atop the same bicycle, are out of the lorry’s path. The other two turn their front wheels in opposite directions to clear the road. Most descriptions of the figures call them girls, perhaps because of their yellow and mint green gowns. They reach for the handlebars of the bicycles, and pedal standing up. Seen from behind, one child’s head appears almost ovoidal, but the others are made parabolic with two-dimensional hair. It is a slice of cacophonous life: one afternoon, a group of barefoot girls are leaving a playground or going to one. Or they are riding their bicycles home from school, racing one another. They enter a major thoroughfare. A lorry approaches, but they are confident enough to outmaneuver it.

more here.