Bryan Walsh in Vox:

Homo sapiens have existed on the planet for about 300,000 years, or more than 109 million days. The most dangerous of all those days — the day when our species likely came closer than any other to wiping itself off the face of the Earth — came 60 years ago today, on October 27, 1962. And the person who likely did more than anyone else to prevent that dangerous day from becoming an existential catastrophe was a quiet Soviet naval officer named Vasili Arkhipov.

On that day, Arkhipov was serving aboard the nuclear-armed Soviet submarine B-59 in international waters near Cuba. It was the height of the Cuban missile crisis, which began earlier that month when a US U-2 spy plane spotted evidence of newly built installations on Cuba, where it turned out that Soviet military advisers were helping to build sites capable of launching nuclear missiles at the US, less than 100 miles away.

That led to the Cold War’s most volatile confrontation between the US and the Soviet Union — 13 days of high-stakes brinkmanship between two nuclear powers that seemed one misstep away from total war.

More here.

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Dennis Zhou at Poetry Magazine:

The astounding influence that Chinese poetry in translation has had on the English language throughout the 20th century—from the Modernist, Imagist revolution of Ezra Pound’s Cathay (1915) through its mid-century, counter-cultural incarnation by Gary Snyder, Kenneth Rexroth, and others—can be traced to this ragtag assortment of drunkards, hermits, and exiles. Very few collections, however, situate the Tang poets fully within their political and historical context, drawing out both the urgency and stakes of their verse. Many anthologies, such as Witter Bynner’s classic The Jade Mountain (1929), simply follow the model of Three Hundred Tang Poems (1763) compiled by the Qing scholar Sun Zhu, which for many decades remained the standard text. In the Same Light (The Song Cave, 2022), translated by the Chinese-Singaporean-Irish poet Wong May, does something different. Collecting 200 poems by 38 poets, Wong May promises to find parallels between their time and the present and, in so doing, update them “for our century.” To do this, she excavates her own story and its resonance with those of the Tang poets.

more here.

Elisa Gonzalez at The Point:

What counts as resurrection? A general rising of the dead, a return from the afterworld at the end of time in some physical embodiment, is specific to a small group of monotheistic religions: Zoroastrianism, Islam, Judaism, Christianity. Irksome sympathizers say that the dead person will “live” in memory. Reincarnation, especially prevalent in the belief systems collected under Hinduism, is an expansive view of resurrection. The “undead”—whether zombies or ghosts—cluster at the threshold of living again. Science fiction and the superrich try to upload the self to a mechanical container. Some physicists propose the eventuality of a quantum resurrection out there in this universe or another. The corpse fertilizes the cemetery grass. What I began seeking, though, was a straight-up rewinding, my own Lazarus, selfsame.

But even Lazarus’s resurrection, a case of supercharged healing, faces the problem of change. Although Lazarus aged like an ordinary man, he supposedly never smiled again.

more here.

https://www.youtube.com/watch?v=U3XwCSTCJfo&ab_channel=WhiteCube

Breakfast with Vananu

My mother had me in Boston but really
by the Beit El checkpoint. I trace my begats
to the burning bush, just blooming henna
but it makes me a citizen of the roadmap.
I just have to fill out the forms. I’ll never escape
the past but at least I can call my kitchen
an embassy, my refrigerator a stockpile
of milk and honey. They carried the promise
around on a palanquin. Remember Nazis
shriveling, rays shooting out between gold angels,
the thing then wheeled to a spot in a warehouse?
He found manna jars labeled Heavy Water
on a shelf and became the last raider
of the lost ark. He leaked the truth
and got eighteen years for assaulting
the holy land with a deadly weapon.
But he can visit me for pancakes and not
violate his house arrest. You should be ashamed,
someone said, and perhaps someone should.
They made Moses wear a veil, his face ablaze
when he walked down the mountain,
its whereabouts classified. It takes God
willing times two hundred to protect
a desert, all my mugs and bowls
waiting for the archaeologists.

by David Moolten
from Pank Magazine, Fall/Winter, 2016

Mordechai Vananu

Jef Akst in The Scientist:

Most models of how tumors evolve have assumed that the process is based predominately on cancer cells’ genetics, and many cancer treatments are specifically targeted to mutations associated with disease. But comparing whole genome sequence data with RNA-seq data from samples of colorectal tumors revealed that the vast majority of gene expression differences among cancer cells cannot be explained by genetics, researchers report in Nature today (October 26).

“So far, a lot of the work that’s been done exploring cancer evolution in cancer development has focused very much on just the genetics,” says Nicholas McGranahan, a computational cancer researcher at the University College London Cancer Institute’s CRUK UCL Centre who was not involved in the research. But according to the new study, “there’s lots of these alterations that they can’t identify a clear [genetic] underpinning for. . . . It’s a nice study because it highlights some of the limitations of what we’ve been doing before.”

Computational biologist Andrea Sottoriva says that it’s those limitations that led him and his colleagues to consider the transcriptome in cancer evolution. “Basically, looking at the genetic evidence was not explaining everything that we were seeing,” says Sottoriva, a group leader at the Institute of Cancer Research, London, and the head of Computational Biology Research Centre at Human Technopole in Milan, Italy. For example, he explains, “if you just look at . . . mutations in genes that are involved in cancer, it’s not very easy to distinguish a benign cancer from a malignant cancer: In a benign cancer, there are as many cancer driver mutations as in a malignant cancer.”

More here.

David Brooks in The New York Times:

Taylor Swift was quite the romantic when she burst on the scene in 2006. She sang about the ecstasies of young love and the heartbreak of it. But her mood has hardened as her star has risen. Her excellent new album, Midnights, plays upon a string of negative emotions — anxiety, restlessness, exhaustion and occasionally anger. “I don’t dress for women,” she sings at one point, “I don’t dress for men/Lately I’ve been dressing for revenge.”

It turns out Swift is part of a larger trend. The researchers Charlotte Brand, Alberto Acerbi and Alex Mesoudi analyzed more than 150,000 pop songs released between 1965 and 2015. Over that time, the appearance of the word “love” in top-100 hits roughly halved. Meanwhile, the number of times such songs contained negative emotion words, like “hate” rose sharply. Pop music isn’t the only thing that has gotten a lot harsher. David Rozado, Ruth Hughes and Jamin Halberstadt analyzed 23 million headlines published between 2000 and 2019 by 47 different news outlets popular in the United States. The headlines, too, grew significantly more negative, with a greater proportion of headlines denoting anger, fear, disgust and sadness. Headlines in left-leaning media got a lot more negative, but headlines in right-leaning publications got even more negative than that.

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Diana Preston in Literary Hub:

The first Europeans to reach Tahiti were the crew of HMS Dolphin, commanded by Samuel Wallis, in June 1767. When the Dolphin approached the island and, like the Beagle, anchored in Matavai Bay, some Tahitians had thought the ship was “a floating island.” Others had recalled a prophecy that, as a result of the chopping down of a sacred tree, newcomers of an unknown kind would arrive and that “this land would be taken by them. The old order will be destroyed and sacred birds of the land and the sea will come and lament what the lopped tree has to dictate. [The newcomers] are coming upon a canoe without an outrigger.”

After some initial friction, Wallis’s crew and the Tahitians became so close that both were sad to see the Dolphin leave, not least on the sailors’ part because of the friendliness of the people, their willingness to trade, the fertility of their island, and most of all because of the ties between some of the crew and Tahitian women who had uninhibitedly made love to them.

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John Horgan in Scientific American:

Studying quantum mechanics, which I’ve been doing for the last two-plus years, has served as an antidote to my tendency toward habituation, taking reality for granted. Wave functions, superposition and other esoterica remind me that this is a strange, strange world; there is a mystery at the heart of things that ordinary language can never quite capture.

I’m thus thrilled by this year’s Nobel Prize for Physics. John Clauser, Alain Aspect and Anton Zeilinger won for experimental probes of entanglement, a peculiar connection between two or more particles. The Nobel Foundation’s press release emphasizes the applications of this prize-winning work; researchers are building “quantum computers, quantum networks and secure quantum encrypted communication” based on entanglement. But I value the work of Clauser, et al., because it upends our commonsense notions about what is real and what is knowable. It rubs our noses in the riddle of reality.

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Adam Tooze in Chartbook:

The politics of inflation in 2022 are surprising.

Perhaps my priors were wrong, but as price indices surge by almost 10 percent I would have expected more talk about the losses inflicted on “small savers” and their vulnerable bank accounts, in other words the classic “petty bourgeois” politics of inflation.

Perhaps the relative lack of such talk points to the fact that no one actually believes that this inflation will be anything more than transitory, so that it amounts not to a landslide devaluation, but a one-off tax on savers and there is thus less reason for panic. Perhaps savers now have more diversified portfolios and are better protected. If so, the collapse in stock market prices hardly offers much comfort.

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Chris Murtha at Art in America:

Much has been written about Diane Arbus—the person and the images—in the 50 years since the Museum of Modern Art mounted its posthumous landmark retrospective of her photographs in November 1972. A recent restaging of that exhibition at David Zwirner, co-organized with Fraenkel Gallery in San Francisco, made visitors acutely aware of the work’s public reception even before entering the exhibition: An introductory note on the gallery windows recounted how the MoMA exhibition “precipitated an eruption of praise and outrage from critics and scholars, a war of words that continues to this day.” Inside, dozens of unattributed quotes wallpapered the lobby, ranging from acidic ridicule to ardent praise. In addition, the exhibition was accompanied by Diane Arbus Documents, a 500-page tome that assembles facsimiles of nearly 70 texts, including exhibition and book reviews, biographical profiles, scholarly essays, and even a master’s thesis. By foregrounding the literature on Arbus, the show acknowledged that the artist’s reputation has often overshadowed her images. Thankfully, it also allowed the photographs to speak for themselves.

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Elena Filipovic at The Brooklyn Rail:

One bleary morning in a darkened art history classroom—think Modernism 101—a slide of the interior of Étant donnés: 1° la chute d’eau / 2° le gaz d’éclairage (1946-1966) flashed by. Its glimmering afterimage remained in my mind’s eye long after. One might say it never really left. I still remember how rattled I was as I tried to make sense of it. The odd installation didn’t fit into what was being taught as modern art at the time, yet conversely—perversely—it nominally coincided with enough of what art history syllabi then encompassed: female nudity mediated by a male gaze, corporeality framed by idyllic landscapes. What perhaps shook me most, however, was that it didn’t tally at all with what I was just learning about the art of its maker. Duchamp, the painter turned cool conceptualist. Duchamp, father of the readymade and chess-playing lover of puns. Duchamp, the sometime art dealer, occasional crossdresser, and elegant prankster who had definitively “retired” by the 1930s. Even if these myriad “Duchamps”already indicated a great flexibility regarding the concept of art and artist, it was Etant donnés, I thought, that didn’t fit. And I was not alone in thinking so.

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An Appointment

Being out of heart with government
I took a broken root to fling
Where the proud, wayward squirrel went,
Taking delight that he could spring;
And he, with that low whinnying sound
That is like laughter, sprang again
And so to the other tree at a bound.
Nor the tame will, nor timid brain,
Nor heavy knitting of the brow
Bread that fierce tooth and cleanly limb
And threw him up to laugh on the bough;
No government appointed him.

by W.B. Yeats
from Running to Paradise
Macmillan Company, 1962

Robin Wright in The New Yorker:

In his fatwas and sermons, Iran’s revolutionary leader, Ayatollah Ruhollah Khomeini, commanded women to hide their bodies and hair from men and “lusting” prepubescent boys. “If this piece of clothing did not exist—the Islamic dress—women could not work in a useful and healthy way,” he said, in a testy exchange with the Italian journalist Oriana Fallaci, in 1979. (She promptly took off her chador, calling it a medieval rag.) Khomeini also recommended that girls be married off before puberty—or the onset of menstruation. “One of the blessings of man,” he said, “is to have his daughter experience her first period not in her father’s house but in that of her husband.” He ruled on sex and marriage and breast-feeding, too. A man who has had sex with his wife after her last menstrual period must wait until after her next one to divorce, although he could proceed if his wife had not yet reached her ninth birthday, was pregnant, or was menopausal. Any wet nurse, the Ayatollah said, should be a “faithful Shi’ite, intelligent, modest, and pretty,” and not “ugly or a bastard.” Every July, Iran officially marks the National Day of Hijab and Chastity.

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Heidi Ledford in Nature:

On 12 September, Amgen announced that the latest trial of sotorasib found that it extended progression-free survival — a measure of the time elapsed without the cancer worsening — only by about one month longer than standard chemotherapy. Only 28% of the participants treated with sotorasib responded to it. That’s roughly twice the number who responded to the standard chemotherapy, but a sign nonetheless that most people who have KRAS-positive lung cancers will not be helped by the new drug.

Even so, the pace of KRAS research and the pursuit of KRAS-targeting drugs has never been so energized, says cancer biologist Channing Der at the University of North Carolina in Chapel Hill. The first glimpse of success has shown that it is possible to drug the ‘undruggable’ KRAS, and now researchers in academia and industry are developing ways to improve their approach. “I have never seen this level of excitement and buzz in the entire history of the field,” he says. “The level now is insane.”

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Jon Wiener at The Nation:

Mike Davis, author and activist, radical hero and family man, died October 25 after a long struggle with esophageal cancer; he was 76. He’s best known for his 1990 book about Los Angeles, City of Quartz. Marshall Berman, reviewing it for The Nation, said it combined “the radical citizen who wants to grasp the totality of his city’s life, and the urban guerrilla aching to see the whole damned thing blow.”

And the whole thing did blow, two years after the book was published. When the Rodney King riots broke out in LA in 1992, frightened white people rushed home, locked the doors, and turned on the TV news. Mike, however, was driving in the opposite direction, with his old friend Ron Schneck at his side. They parked, got out, and started talking with the people in the streets about what was going on. Then he went home and wrote about it.

more here.

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