The Unexemplary Simone Weil

Alexa Hazel at The Point:

Simone Weil was difficult for those who knew her in life and no less difficult for those who encounter her now, through the writings that survived her death at the age of 34 in 1943. Robert Zaretsky’s new intellectual biography, The Subversive Simone Weil: A Life in Five Ideas (2021), evokes several difficulties in its epilogue. Weil’s character was “extreme.” Her ideas were largely impractical (“at worst inhuman”). He calls her attitude “merciless.” And yet, “I cannot resist returning time and again to this remarkable individual,” Zaretsky writes. She led an “exemplary” life. “For many of her readers,” he suggests, “Weil’s life has all the trappings of secular sainthood.”

Some do take a strong stance on Weil (saint, insane). Many more find themselves in what Zaretsky calls an “untenable position.” T.S. Eliot alludes to Weil’s “great soul” several times in his preface to the English translation of The Need for Roots. Eliot echoes Albert Camus, who collected and published much of Weil’s work after her death, and once called her “the only great spirit of our time.”

more here.



What can the decline of the Roman Empire and the end of European feudalism tell us about COVID-19 and the future of the West?

John Rapley in Aeon:

Neo-Malthusians credited environmental feedback loops, not moral failings, for regime collapse. In the 1960s and ’70s, works by Paul Ehrlich and Donella Meadows et al argued that the world’s population was growing so fast it would soon outstrip resource supplies, leading to (among other things) widespread food shortages. More recently, Jared Diamond wrote of the role that environmental depletion and diseases played in the fall of civilisations, and his theory that the collapse of Easter Island resulted from overexploitation of the natural environment has enjoyed particular resonance. For its part, the COVID-19 pandemic revived old theories about the role that diseases played in regime collapse, and we were reminded that plagues had laid low the Roman Empire and destroyed European feudalism.

Except, that wasn’t what happened. At least, not quite the way supposed.

More here.

Animals Can Count and Use Zero. How Far Does Their Number Sense Go?

Jordana Cepelewicz in Quanta:

Practically every animal that scientists have studied — insects and cephalopods, amphibians and reptiles, birds and mammals — can distinguish between different numbers of objects in a set or sounds in a sequence. They don’t just have a sense of “greater than” or “less than,” but an approximate sense of quantity: that two is distinct from three, that 15 is distinct from 20. This mental representation of set size, called numerosity, seems to be “a general ability,” and an ancient one, said Giorgio Vallortigara, a neuroscientist at the University of Trento in Italy.

Now, researchers are uncovering increasingly more complex numerical abilities in their animal subjects. Many species have displayed a capacity for abstraction that extends to performing simple arithmetic, while a select few have even demonstrated a grasp of the quantitative concept of “zero” — an idea so paradoxical that very young children sometimes struggle with it.

More here.

The Truth About Intervening Powers in the Middle East

Trita Parsi and Matthew Petti in The American Prospect:

Reviewing all of the region’s military interventions between 2010 and 2020, our research shows that several powerful states in the region intervene militarily in the affairs of their neighbors to roughly the same degree, defying the idea that the region’s instability can be blamed on a single pariah state.

Among these states—Iran, Israel, Qatar, Saudi Arabia, Turkey, and the United Arab Emirates—there is no outlier. While Washington has fixated on Tehran’s interventions, the data shows that the UAE and Turkey have of late outdone Iran in terms of military meddling in the affairs of their neighbors. Iran’s support for militias in Iraq and Lebanon has grabbed headlines in the American media, but the UAE has quietly been building its own international mercenary army with the help of contractors like Erik Prince, and Turkey has shuttled fighters from Syria to Libya and Nagorno-Karabakh.

More here.

How the ‘sponge’ made by the bacteria Geobacter soaks up uranium

Matt Davenport in Science:

For decades, scientists suspected that bacteria known as Geobacter could clean up radioactive uranium waste, but it wasn’t clear how the microbes did it.

“The biological mechanism of how they were doing this remained elusive for 20 years,” said Gemma Reguera, the Spartan microbiologist whose team solved that mystery 10 years ago. Well, three-quarters of the mystery. She’s now cracked the rest of the case. What Reguera discovered in 2011 was that, on one side of their cells, the Geobacter make protein filaments that act like little wires to literally zap uranium. This does two things. For one, the jolt triggers chemical reactions that give the bacteria energy. Secondly, that chemistry traps the uranium in a mineral form, preventing the radioactive material from spreading through the environment. But those protein wires accounted for just about 75% of the uranium that the Geobacter were cleaning up.

“We always knew we were missing something,” said Reguera, a professor of microbiology and molecular genetics in the College of Natural Science. “What we didn’t know was what was happening at the cell surface, particularly on the side of the cell that had no wires to immobilize the uranium.”

Now, Reguera’s team has the answer. Molecules called lipopolysaccharides coat the cell surface and soak up the uranium like a sponge.

More here.

Deciphering the molecular language of the small intestine

Marco Jost in Nature:

Our main goal is to begin deciphering the molecular communication between bacteria (and the small molecules they secrete) and host cells in the small intestine. We’re particularly interested in enteroendocrine cells — cells found in the lining of the small intestine and throughout the intestinal tract — and how the small-intestine microbiome prompts them to release hormones. We also want to explore how this communication allows gut bacteria to alter physiology throughout the body. We know that gut bacteria affect biological processes in distal places such as the brain and skeletal muscles. I believe that bacterial communication with enteroendocrine cells is a major mechanism. These cells secrete hormones and neurotransmitters, and they also talk to neurons, sending signals across the body. We know there are physical interactions, where bacteria adhere to host cells. There are also chemical-signaling interactions, where intestinal cells sense and react to small molecules produced by microbes. We don’t yet understand the full context or implications of this molecular language in the small intestine. We hope to begin probing which small molecules the enteroendocrine cells respond to, which bacteria produce these molecules, which receptors they bind to, and how that translates to changes in biological processes. Our hope is to provide valuable novel therapeutic targets, not just for metabolic disorders, but also for neuropsychiatric conditions, and disorders influenced by the microbiome.

What cells and molecules will you focus on?

The small intestine is an incredibly dynamic environment, and we know that diet is a key influence on small-intestine activity. We also know there is a rich diversity of enteroendocrine cells in the small intestine, and that the chemical landscape is very interesting. There are different types of enteroendocrine cells, each with its own specialized function. Most commonly, they each secrete a different hormone in response to external prompts such as diet.

More here.

Thursday Poem

Manic Screaming

We should make all spiritual talk
…. Simple today:

God is trying to sell you something,
…. But you don’t want to buy.

This is what your suffering is:

Your fantastic haggling,
…. Your manic screaming over the price!

by Hafiz
from
I Heard God Laughing
Penguin Books, 2006

Wednesday, August 11, 2021

Dear Porch: Everybody Wants Some!! & The Green Ray

Morgan Meis in The Porch Magazine:

I’m not gonna say that Everybody Wants Some!!, the film by Richard Linklater, is a great movie. It is not. But it’s pretty good. We should also just appreciate a film that has not one but two!! exclamation marks in its official title. And yet, something nags at me about the title, that sentence, everybody wants some. What is it that everybody wants? Some. Some what? Well sex, of course, everbody wants some sex. And most of the people in the film are chasing after sex, especially the jocks on the baseball team, our ostensive heroes, the protagonists of the film if there are any protagonists in this film. They want to have as much sex as possible, those baseball jocks, and a few of them get just that. They also want something to do with baseball. They want to become baseball players of a professional sort. They want some fame, some glory, the glory of sport. Probably they want some money also, the money that goes along with the glory and that overlaps to at least some degree with the sex. Sex, glory, and money. That is what they want some of.

One amazing thing that Linklater achieves in the film, to my mind, dearest Porch, I don’t know if you had the same experience with the film, but I’ve noticed that many reviewers of the film say something along these same lines, they say that you can’t really dislike these jocks. It is a funny point but one I’d have to agree with.

More here.

Hopeful News: Neutralizing the SARS-CoV-2 sugar coat

From Phys.org:

The road from SARS-CoV-2’s “immunity shield” or “sheep’s clothing” to its Achilles’ heel involved several state-of-the-art research techniques. In collaboration with Peter Hinterdorfer of the Institute of Biophysics at the University of Linz, Austria, the team used high-tech biophysical methods to analyze how the lectin binding takes place in detail. For example, the researchers measured which binding forces and how many bonds occur between the lectins and the Spike protein. This also made it clear to which sugar structures Clec4g and CD209c attach.

More good news: The team found that the two lectins bind to the N-glycan site N343 of the Spike protein. This specific site is so crucial to the Spike that it can never be lost in any infectious variant. In fact, a deletion of this glycosylation site renders the Spike protein unstable. In addition, other groups have also shown that viruses with mutated N343 were non-infectious. “This means that our lectins bind to a glycan site that is essential for Spike function—it is therefore very unlikely that a mutant could ever arise that lacks this glycan,” explains Mereiter.

More here.  And see this too.

A Different Sense of Privilege

Steve Lagerfeld in The Hedgehog Review:

In the 1980s, I got to know a man who seemed to be the walking embodiment of privilege. He was an elderly but vigorous WASP, tall and lean, with ancestry in this country that reached back to the seventeenth century. A Princeton man, he had gone into finance and risen to become CEO and chairman of a major regional bank. He had one of those WASP names one can barely resist satirizing, but he had been known all his life by his childhood nickname, Curly.

This was just the first hint that this man was something of an anomaly. (Curly was also, inevitably, almost entirely bald.) Long retired by the time I met him, he had chalked up the expected array of civic and charitable activities during his career. But in retirement he was pursuing with characteristic energy an assortment of more hands-on volunteer jobs. One of them in particular struck me. He was a hospital orderly, pushing carts here and there, assisting patients’ families, and doing various tasks too small or tedious for the nursing staff. “A candy striper,” he joked. As far as I know, he was never asked to empty bedpans, but I’m pretty sure he would have done it.

Where, I have often wondered, does such a spirit of service come from? How could it be revived? Today’s elites are often generous givers of money, yet it’s hard to imagine, say, Bill Gates, a magnificently prolific philanthropist, pushing a cartful of sheets and towels down a hospital corridor.

More here.

The Canadian Poetry of Marie Uguay

Ben Libman at Poetry Magazine:

The 1980 reading—one of the few scenes etched in the history of Québécois literature—also marked the public debut of Marie Uguay, a 25-year-old poet with two published collections. Her brief appearance, halfway through the night’s program, proved the apex of her meteoric streak as a writer. It took all of four minutes—and it was audible. The third of four poems she recited, which begins “And yet oranges and apples do exist” and ends “Gently Cézanne claims his kinship with the earth’s suffering / with its structures / and all of summer’s vitality comes to wake me / comes gently passionately to bequeath its every fruit to me,” gave way to thunderous applause. It was as if a switch had been flipped, the suddenness with which a public epiphany descended palpably upon the room: This is a poet.

Yet, Uguay was not to enjoy the rites of a major artist. She did not have a long career punctuated by award ceremonies, readings, and frequent publications. The year after her reading at La nuit de la poésie, at age 26, she died of cancer, having just put together her third collection.

more here.

Danish Siddiqui (1983–2021)

Skye Arundhati Thomas at Artforum:

“No one who saw the photo thought I would survive,” said Mohammad Zubair, describing an image, taken by Siddiqui, which came to define last year’s anti-Muslim pogrom in New Delhi. Zubair was beaten by a mob of Hindu men, many wearing bike helmets. “It was like a war zone,” Siddiqui said, recounting how he had walked over the rubble of broken bricks and batons. He stood about a yard away from the group, his mask flecked with Zubair’s blood. He was spotted, and the attackers paused, looking right at his camera. Siddiqui fled just as Zubair lost consciousness. A group of young Muslim boys found Zubair and asked the neighborhood doctor to perform emergency stitches on his head wounds. Siddiqui looked for him later, relieved to find him alive in a local hospital. He made a portrait against the pale blue wall of the intensive treatment wing, Zubair’s head wrapped in gauze, eyes bruised and swollen. Siddiqui often said that he photographed “the human face of a breaking story.”

more here.

Andrew Cuomo’s Resignation and the Real Meaning of “New York Tough”

Amy Sorkin in The New Yorker:

It was embarrassingly obvious that Governor Andrew Cuomo wanted the address, on Tuesday, in which he announced his resignation, in the face of allegations of sexual harassment, to stir up memories of his pandemic press conferences. Within a sentence or so, he was talking about “New York tough,” and he used the phrase—a rallying cry in the days when ambulance sirens were the signature sound of New York City—as the organizing rhetorical device for his speech. But it’s worth suggesting a different point of reference. Compare the image of Cuomo now with that of the Governor almost three years ago, on September 7, 2018, at the “grand opening” of a replacement for the Tappan Zee Bridge, which he had managed to rename the Governor Mario M. Cuomo Bridge, after his father. To celebrate, he drove across the new span with one of his daughters, Cara, and his then partner, Sandra Lee, in a 1932 Packard convertible that had belonged to Franklin D. Roosevelt, who had been the governor of New York before he became President.

Did Cuomo hope that he might follow in F.D.R.’s path? Almost certainly. Did the state pay more than ten thousand dollars to make F.D.R.’s Packard roadworthy so that the Governor could drive it on ceremonial occasions? It did. Did Cuomo also hope that people might eventually just start calling the bridge the Cuomo Bridge, and be surprised to learn that it was named for Mario, rather than Andrew? Possibly, unless he had a vision of the Manhattan or Brooklyn Bridge renamed for him. Does Cuomo have an issue with his father’s legacy that he seems to play out through political games in which he must be the center?

More here.

Why your sleeping brain replays new rewarding experiences

Jim Davies in Nautilus:

During this Olympics, I’ve been rooting for Kelleigh Ryan, who is on the women’s foil team. She’s from Ottawa, where I live. Whenever she scored a point, she’d emit a victory scream, probably feeling a rush of pleasure. Watching her on television, I did, too. Getting better at something involves emotion. When we do well, we have good feelings—pride, pleasure, excitement—and these emotions help reinforce whatever behaviors we just engaged in. Similarly, the pain of failure makes recent behaviors less likely in the future. This is conditioning, and we’ve all experienced it—when we’re awake. But what about when we sleep?

Sleep reinforces memories. We know this because after half an hour of sleep, people can remember things better than when they spend half an hour doing something else, like watching TV. Studies of rats show that their brains rehearse running through mazes while they sleep, in a process known as sleep replay. Memory’s function is to store information that will be useful. Because of this, our mind prioritizes remembering some things over others. Studies have shown, for example, that it’s easier to remember things that are useful for survival. Might sleep similarly focus on things that are particularly good or bad for us, like food and dangerous animals, and ignore things that are irrelevant to our well-being, like the exact shape of a cloud?

A recent study by the University of Geneva’s Virginie Sterpenich and colleagues tried to find out. They had subjects play two computer games, which were designed to be engaging and to use two very different brain areas.

More here.

Wednesday Poem

The Love for my Culture

Maybe it’s the Spanish running through my veins
That’s the only way I know how to explain it
Maybe it’s the r’s rrrolling off my tongue
See,
When I speak in Spanish
It takes the air from my lungs
The love for my culture reaches the sky
The love for my culture will never die
And while you get up and have your milk and cereal
Siempre desayuno con platano de mangu
Not no cheerios
I always mix it up
Con salsa y merengue
Constantly side ways glanced at
Like, she speak no ingles
Yo si puedo hablar, ingles y espanol
Hasta puedo entender dos y tres
Languages!
Confronted with problems like immigration
Forced to have my parties down in the basement
Confined to the more popular story that my family
Criss, crossed, and slid past borders
Trying to find a new place to live
Guilty of chasing paper
without papers
but when that visa is blinking green
It’s saying
“Go, go m’jita! Fight for your dreams!”
Read more »

Tuesday, August 10, 2021

The Silver Age of Essays

Phillip Lopate in The Paris Review:

The first quarter of the twenty-first century has been an uneasy time of rupture and anxiety, filled with historic challenges and opportunities. In that close to twenty-five-year span, the United States witnessed the ominous opening shot of September 11, followed by the seemingly unending Afghanistan and Iraq wars, the effort to control HIV/AIDS, the 2008 recession, the election of the first African American president, the legalization of same-sex marriage, the contentious reign of Donald Trump, the stepped-up restriction of immigrants, the #MeToo movement, Black Lives Matter, and the coronavirus pandemic, just to name a few major events. Intriguingly, the essay has blossomed during this time, in what many would deem an exceptionally good period for literary nonfiction—if not a golden one, then at least a silver: I think we can agree that there has been a remarkable outpouring of new and older voices responding to this perplexing moment in a form uniquely amenable to the processing of uncertainty.

When the century began, essays were considered box office poison; editors would sometimes disguise collections of the stuff by packaging them as theme-driven memoirs. All that has changed: a generation of younger readers has embraced the essay form and made their favorite authors into best sellers.

More here.

New IPCC Report Provides Unprecedented Clarity About Earth’s Climate

Ethan Siegel in Forbes:

CO2 concentrations now sit at 412 ppm, Earth’s temperature is a full 1.3 °C (2.3 °F) above pre-industrial levels, and still, no meaningful, sustained initiatives to reduce our global carbon emissions have been taken. In fact, they’re presently at an all-time high. The longer we delay meaningful climate action, the more severe the consequences will get not just for all of humanity today, but for generations and even millennia to come. Although our climate future intimately depends on how global emissions unfold in the coming years and decades, the latest IPCC report provides unprecedented clarity on a number of important issues. Here are the top six takeaways we should all accept and understand.

More here.