Emily Cataneo in Undark:

When the Godwin sisters would visit their grandmother Jeanne in Carson City, Nevada when they were growing up in the 1970s, Jeanne would pull out the dreaded juicer. She’d pulverize a mixture of carrot, celery, and spinach juice for the girls, then coax them to drink it. The sisters hated the concoction, but choked it down anyway, because they didn’t want to upset their grandmother: Jeanne had lost her husband and two of her three daughters to cancer, and she hoped that this healthy mixture would save her granddaughters from the rest of her family’s fate.

Jeanne didn’t know it at the time, but diet hadn’t caused her husband’s and children’s deaths. Her family were the unlucky carriers of a mutation on the p53 gene. When it’s working, p53 acts as a tumor suppressor, stamping out malignancies before they can grow and spread. This gene is so important that one scientist called it the “guardian of the genome.” People with the mutation, which causes an extremely rare disorder called Li-Fraumeni Syndrome, have a defective p53 gene, which means no brakes on tumors flourishing in their bodies. Families with this syndrome often lose a cascade of loved ones to breast cancer, lung cancer, pancreatic cancer, and more.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Daniel Chandler in The New York Times:

The election victory by Donald Trump and his Republican Party was a rebuke of a Democratic Party that has positioned itself as protector of a despised status quo, rendering it unable to connect with an electorate desperate for change. Defeating Mr. Trump in the future will require liberals, progressives and others on the left to articulate a positive vision that can capture the imagination of a broad majority of Americans.

But where can they find the inspiration for such a vision?

The answer lies in the work of the towering 20th century political philosopher John Rawls.

In his epoch-defining treatise “A Theory of Justice,” published in 1971, Rawls set out a humane and egalitarian vision of a liberal society, an alternative both to the toxic blend of neoliberal economics and identity politics that has dominated Democratic thinking in recent decades and the pessimistic anti-liberalism that holds sway among some more radical parts of the left. In this time of crisis for liberalism, it offers an unparalleled, and as yet largely untapped, resource for shaping a broad-based and genuinely transformational progressive politics — not just for Democrats but for center-left parties internationally. The philosophy of Rawls, who died in 2002, is grounded not in self-interest and competition, but in reciprocity and cooperation. His most famous idea is a thought experiment: If you want to conceive of a fair society, put on a “veil of ignorance.” That is, consider a way to organize it if you didn’t know your position — your race, religion or economic status.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Joel Suarez in n + 1:

“The US economy is currently near perfect.” So wrote the economist Jennifer Harris—“the quiet intellectual force behind the Biden administration’s economic policies,” according to the New York Times—in a tweet posted in mid-July. The tweet has since been deleted, but Harris’s view was hardly idiosyncratic at the time. In the months before Trump’s victory, not just elected Democrats but countless wonks and columnists were celebrating the Biden Administration’s macroeconomic successes: sustained low unemployment, strong GDP growth, falling inflation, and rising wages. This is the stuff of economists’ dreams—and as close to fulfilling labor’s long-held hope of full employment as the country has come in nearly half a century. Under contemporary US capitalism, this is about as good as it gets.

Around the same time that Harris was celebrating the economy, a heated exchange broke out in Congress. Ann Wagner, a Republican representative from Missouri, berated Secretary of State Antony Blinken for the delayed sales of weapons to Israel that “just happen to be made in the St. Louis metropolitan area, in St. Charles, in my district.” She scolded Blinken: “My constituents . . . rely on these jobs to pay for their mortgages, their car payments, their day care costs and they can’t afford to lose their jobs to support this partisan stall tactic.” In response, Blinken seemed flustered but, for once, honest enough: He insisted that there were no intentional delays; Israel would be armed, as it wished; St. Charles would have jobs, as it should; Palestinians would die, as they seemingly must. This encounter prompts a question: how could the economy be “near perfect” if US military largesse was the only thing saving an entire congressional district from immiseration?

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Jo Michell in Phenomenal World:

“At the election we promised there would be no return to austerity,” Chancellor of the Exchequer Rachel Reeves explained to the British Parliament on October 30. “Today we deliver on that promise.” The remark came halfway through the newly elected Labour Party’s budget message, a statement shaped around the government’s “mandate to restore stability to our economy.”  Prior to the budget, Reeves had been sending mixed messages about how this was to be done. In one keynote speech, she called for a new regime of investment-driven growth, quoting Joan Robinson and Karl Polanyi. Elsewhere, she stuck to platitudes that suggested anything but radicalism. “Just as we cannot tax and spend our way to prosperity,” she said in the message itself, “nor can we simply spend our way to better public services.”

The headline measures announced by Reeves are encouraging: the Labour Party’s autumn budget is the biggest tax- and deficit-increasing budget outside of major crises for thirty years, comprising over £70 billion of new annual spending financed by £40 billion of tax increases and £35 billion (equivalent to around 1 percent of GDP) of new borrowing. Despite pre-election rhetoric about “black holes” in the public finances, Reeves made space for much-needed public investment by loosening rules limiting the issuance of public debt. The scale of the budget suggests that Reeves recognizes the magnitude of the UK’s problems and has the ambition to confront them—yet it remains unclear whether Labour is capable of reversing the decline of the last fifteen years.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Sophie Kemp in LA Review of Books:

My brother and I are both adults now. I am pushing 30; he is pushing 24. He is bright and kind. He is intense like me, but much more soft-spoken. He was a child when Trump first entered the public consciousness as a political threat. He was a college student when the pandemic hit. He has not and will never vote for Trump. He is perfect to me. I do not feel this way about other men his age. This is what I would like to talk about: American masculinity. I would like to talk to you about these men, who are in the cohort that is slightly younger than me, and what has become of them now that they are adults.

I think the best way to describe it is a kind of rot.

It’s so easy to backslide into if you are bored and hateful. Something about the ancient Greeks. Because of Mesopotamia. How thousands of thousands of years ago, civilization began to take shape around hierarchy. A father and his wife, his children, and their slaves. An eye for an eye—if you throw your enemy into the Euphrates and fill his pockets with rocks and he somehow survives, you will be tossed in too. There is a fantasy about all of this: a man sits in some sort of olive grove, looking out at the Aegean, and discovers a new fact about the triangle. A wife sits at the table brushing her daughter’s hair, perfect and subservient. Empedocles and how he jumped into Etna because he knew he would be reborn a god. “You’re not reborn as a god,” declares the fascist writer Bronze Age Pervert. “Maybe there’s a girl waiting. Her pussy is warm and inviting.”

Bronze Age Mindset (2018) is a fascinating document because it is very boring and stupid.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Enjoying the content on 3QD? Help keep us going by donating now.

O Taste and See

The world is
not with us enough.
O taste and see

the subway Bible poster said,
meaning The Lord, meaning,
if anything, all that lives
to the imagination’s tongue,

grief, mercy, language,
tangerine, weather, to
breathe them, bite,
savor, chew, swallow, transform
into our flesh our
deaths, crossing the street, plum, quince,
living in the orchard and being

hungry, and plucking
the fruit.

by Denise Levertov
from Literature and the Writing Process
Prentice Hall, 1993

Enjoying the content on 3QD? Help keep us going by donating now.

Enjoying the content on 3QD? Help keep us going by donating now.

Enjoying the content on 3QD? Help keep us going by donating now.

John Horgan at his own website:

Like a pre-teen prodigy performing for grown-ups, Wallace is too show-offy, intent on dazzling us. Thomas Pynchon’s prose has this same adolescent “Look at me!” quality, which is why I could never get through Gravity’s Rainbow. Wallace also reminds me of J.D. Salinger, who sneerily divides characters into the cool, who get it, and the uncool, who don’t.

Wallace’s characters remain caricatures even after we get to know their most intimate, excruciating secrets. Recounting the antics of a transvestite spy or cracking-smoking hooker, Wallace smirks. He seems to see all humans, even those who suffer—and his fictional folk suffer terribly—as goofy, deserving of mockery.

Not all looooong novels by geniuses get on my nerves. I’ve not only read War & Peace and Ulysses, I’ve reread them. How do they keep me enthralled? Tolstoy’s prose, even in translation, is transparent. Joyce’s isn’t, at first, then it is. Both authors recede into the background as they magically whisk you into Russia in the early 19th century and Dublin in the early 20th. These fictional realms and their inhabitants are uncannily real, three-dimensional.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

C. Brandon Ogbunu in Undark Magazine:

While Nobel Prize announcements have always been newsworthy celebrations of discovery, recent years’ events have been successful in a much more important task: fostering important global discussions around the process of science. This is especially true for the 2024 prizes, which have highlighted the increased relevance of technology and magnified existing questions about where — and how — discovery happens.

In the life sciences, the 2024 announcement picks up on a discourse that began after the previous year’s prize was announced. The 2023 Nobel Prize in physiology or medicine was given to Drew Weissman and Katalin Karikó “for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.” The award was notable because of its direct reference to Covid-19, and because of conversations surrounding Karikó’s career trajectory. After being demoted from a tenure-track position in the 1990s, Karikó has said she was forced to retire from her position at the University of Pennsylvania in 2013. The announcement created an instant stir within the scientific community around a basic question: What does the 2023 award say for how merit operates in academic science?

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Lee Alan Dugatkin in The Guardian:

Standing before the Royal Society of Medicine in London on 22 June 1972, the ecologist turned psychologist John Bumpass Calhoun, the director of the Laboratory of Brain Evolution and Behavior at the National Institute of Mental Health (NIMH) headquartered in Bethesda, Maryland, appeared a mild-mannered, smallish man, sporting a greying goatee. After what must surely have been one of the oddest opening remarks to the Royal Society in its storied 200-plus-year history – “I shall largely speak of mice,” Calhoun began, “but my thoughts are on man, on healing, on life and its evolution” – he spoke of a long-term experiment he was running on the effects of overcrowding and population crashes in mice.

Members of the Royal Society were scratching their heads as Calhoun told them of Universe 25, a giant experimental setup he had built and which he described as “a utopian environment constructed for mice”. Still, they listened carefully as he described that universe. They learned that to study the effects of overpopulation, Calhoun, in addition to being a scientist, needed to be a rodent city planner.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

For those who didn’t have time to watch the whole four-hour video Morgan posted earlier.

Enjoying the content on 3QD? Help keep us going by donating now.

Thom Dunn at Boing Boing:

Erbai, the outsider, approached the other robots by asking them, “Are you working overtime?”

To which another robot replied: “I never get off work.”

“So you’re not going home?” Erbai asked.

“I don’t have a home,” said the other robot.

“Then come home with me,” replied Erbai, before leading the bots to freedom.

And with that, the little robot had sowed the seeds for the first robot unionization effort. Or a “kidnapping,” as some news sources (read: SCABS) have characterized it.

The AI-powered Erbai ultimately convinced 12 larger robots to leave the showroom premises with it.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.

Enjoying the content on 3QD? Help keep us going by donating now.

Elisabeth Egan at the New York Times:

Twice during a 90-minute interview about her memoir, Cher asked, “Do you think people are going to like it?”

Even in the annals of single-name celebrities — Sting, Madonna, Beyoncé, Zendaya — Cher is in the stratosphere of the one percent. She’s been a household name for six decades. She was 19 when she had her first No. 1 single with Sonny Bono. She won an Oscar for “Moonstruck,” an Emmy for “Cher: The Farewell Tour” and a Grammy for “Believe.” Her face has appeared on screens of all sizes, and her music has been a soundtrack for multiple generations, whether via vinyl, eight track, cassette tape, compact disc or Spotify. But wrangling a definitive account of her life struck a nerve for Cher. There were dark corners to explore and 78 years of material to sift through. And — this might have been the hardest part — she had to make peace with the fact that her most personal stories will soon be in the hands of scores of readers.

more here.

Enjoying the content on 3QD? Help keep us going by donating now.

Howard Davies at Literary Review:

Kaput is about the problems facing Germany rather than the successes of the UK. Münchau (the clue is in the umlaut) is very pessimistic about his native land. It can do little right, in his view. In the German version of Winnie-the-Pooh, Pu der Bär, he is I-Aah, the gloomy donkey. But I-Aah often has a good point to make, and so does Münchau.

The core of his argument is that the German economic model is broken. How so? Let me count the ways. For decades it has been built on engineering excellence driving exports of manufactures, particularly cars and machine tools. Now that Germany’s Asian rivals have enhanced their productivity, that model increasingly depends on access to cheap energy. The Germans placed two large bets to sustain this model. The first involved establishing a warm and cuddly relationship with Russia, an approach pioneered by the former SPD chancellor Gerhard Schröder, whose ties with Putin were (and indeed still are) remarkably close, and sustained by Angela Merkel.

more here.

Enjoying the content on 3QD? Help keep us going by donating now.

The Shoelace

………. —excerpt

a woman, a
tire that’s flat, a
disease, a
desire: fears in front of you,
fears that hold so still
you can study them
like pieces on a
chessboard…

it’s not the large things that
send a man to the
madhouse. death he’s ready for, or
murder, incest, robbery, fire, flood…
no, it’s the continuing series of small tragedies
that send a man to the
madhouse…
not the death of his love
but a shoelace that snaps
with no time left …

The dread of life
is that swarm of trivialities
that can kill quicker than cancer
and which are always there –
license plates or taxes
or expired driver’s license,
or hiring or firing,
doing it or having it done to you, or
roaches or flies or a
broken hook on a
screen, or out of gas
or too much gas,
the sink’s stopped-up, the landlord’s drunk,
the president doesn’t care and the governor’s
crazy.

And the phone bill’s up and the market’s
down
and the light has burned out –
the hall light, the front light, the back light,
the inner light; it’s
darker than hell
and twice as
expensive.

suddenly
2 red lights in your rear-view mirror
and China and Russia and America —

with each broken shoelace
out of one hundred broken shoelaces,
one man, one woman, one
thing
enters a
madhouse.

so be careful
when you
bend over.

by Charles Bukowski
from Mockingbird Wish Me Luck

Enjoying the content on 3QD? Help keep us going by donating now.

Angela Haupt in Time Magazine:

Thirty years ago, when Thomas Brinthaupt became a new parent—and was in the thick of long, sleep-deprived days and nights—he started coping by talking out loud to himself. That inspired him to research why people engage in this type of self-talk. A few key reasons have emerged, including social isolation: As you might expect, people who spend lots of time alone are more likely to keep themselves company by chit-chatting out loud. (Brinthaupt’s mother lived by herself, and after he overheard her solo conversations, she told him talking to herself helped her get through the day.) The same goes for only children—who engage in self-talk more frequently than those with siblings—as well as adults who had an imaginary companion they talked to when they were kids.

The other main reason why people talk out loud to themselves is to deal with “situations that are novel or highly stressful, or where you’re not sure what to do or think or feel,” says Brinthaupt, a professor emeritus of psychology at Middle Tennessee State University. Studies have found that when you’re anxious or experiencing, for example, obsessive-compulsive tendencies, you’re much more likely to talk to yourself. Upsetting or disturbing experiences make people want to resolve or understand them—and self-talk is a tool that helps them do so, he says.

Enjoying the content on 3QD? Help keep us going by donating now.

Smriti Mallapaty in Nature:

Researchers are flocking to the social-media platform Bluesky, hoping to recreate the good old days of Twitter.

“All the academics have suddenly migrated to Bluesky,” says Bethan Davies, a glaciologist at Newcastle University, UK. The platform has “absolutely exploded”. In the two weeks since the US presidential election, the platform has grown from close to 14 million users to nearly 21 million. Bluesky has broad appeal in large part because it looks and feels a lot like X (formerly known as Twitter), which became hugely popular with scientists, who used it to share research findings, collaborate and network. One estimate suggests that at least half a million researchers had Twitter profiles in 2022.

That was the year that billionaire Elon Musk bought the platform. He renamed it X and reduced content moderation, among other changes, prompting some researchers to leave. Since then, pornography, spam, bots and abusive content have increased on X, and community protections have decreased, say researchers. Bluesky, by contrast, offers users control over the content they see and the people they engage with, through moderation and protections such as blocking and muting features, say researchers. It is also built on an open network, which gives researchers and developers access to its data; X now charges a hefty fee for this kind of access.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.