Lydia Denworth in Scientific American:

A connection between the human herpesvirus Epstein-Barr and multiple sclerosis (MS) has long been suspected but has been difficult to prove. Epstein-Barr virus (EBV) is the primary cause of mononucleosis and is so common that 95 percent of adults carry it. Unlike Epstein-Barr, MS, a devastating demyelinating disease of the central nervous system, is relatively rare. It affects 2.8 million people worldwide. But people who contract infectious mononucleosis are at slightly increased risk of developing MS. In the disease, inflammation damages the myelin sheath that insulates nerve cells, ultimately disrupting signals to and from the brain and causing a variety of symptoms, from numbness and pain to paralysis.

To prove that infection with Epstein-Barr causes MS, however, a research study would have to show that people would not develop the disease if they were not first infected with the virus. A randomized trial to test such a hypothesis by purposely infecting thousands of people would of course be unethical.

Instead researchers at the Harvard T. H. Chan School of Public Health and Harvard Medical School turned to what they call “an experiment of nature.” They used two decades of blood samples from more than 10 million young adults on active duty in the U.S. military (the samples were taken for routine HIV testing). About 5 percent of those individuals (several hundred thousand people) were negative for Epstein-Barr when they started military service, and 955 eventually developed MS.

More here.

Justin E. H. Smith in his Substack newsletter, Hinternet:

Nobody wants to hear anyone else’s dreams, and nobody wants to see anyone else’s photo albums. A rare few good souls might express interest at first, but will almost certainly find their attention flagging long before the sharer is finished.

As to dreams, the claim can be measured each time a person takes to social media to divulge the surreal sequence from which they’ve just awoken. I’ve been keeping track, and have observed that consistently and without exception they get fewer likes for their dreams than when telling stories from their waking life, or telling jokes, or lies. You can see, in that mysterious way social media telegraphically transmits distant affects, that the dream-sharers regret their decision, resolve never to do it again, only to find, the next time they wake up from naked bumper-cars with their camp counselors from childhood, that they just can’t help themselves, and the cycle of oversharing and regret begins again.

As to family photos, let us be honest: they all look the same.

More here.

Tomas Pueyo in his Substack newsletter, Uncharted Territories:

After the Omicron wave, we’ll be in a world where most people will have some sort of immunity, either through natural infections, vaccines, or both. We now know how to get vaccines fast (we should approve them faster for new variants), and we have treatments too. The value of time for learning has dropped: we know most of what we need to know about it. So the benefits of social measures to stop COVID are much lower.

Meanwhile, the costs of stopping COVID are much higher, because Omicron escapes immunity and is extremely transmissible. It’s much, much harder to stop a COVID wave now than it was two years ago. Look at how China is desperately trying to stop the virus but can’t without drastic lockdowns.

Lower benefits, higher costs: the ROI (return on investment) of tackling COVID with social measures has reversed. And from now on, it’s not going to get any better.

More here.

Sarah Ogilvie in Prospect:

We can pinpoint the moment the meaning of woke changed: July 2020. Phrases such as “stay woke,” “be woke,” “woke people,” “woke culture,” “woke af (as fuck)” (as in “the best thing about having a lesbian grandma is that she is woke af”) were now replaced by the markedly negative “woke agenda,” “woke mob,” “woke ideology,” “woke brigade,” “woke police.” New negative derivatives such as wokeness, wokeism, wokester and wokery began to circulate. As the meaning of woke changed, the word became far more heavily used. From January 2020 to January 2021, it became four times more popular on the internet and in newspapers.

So who exactly took control of woke in July 2020, and how did they turn it into a four-letter word? Digging into big data tells us.

More here.

Atlantic City, June 23, 1957 (AP) — President Eisenhower’s pastor said tonight that Americans are living in a period of “unprecedented religious activity” caused partially by paid vacations, the eight-hour day, and modern conveniences.

“These fruits of material progress,” said the Reverend … of the National Presbyterian Church, Washington, “have provided the leisure, the energy, and the means for a level of human and spiritual values never before reached.”

… Sees boom in religion to.

Boom

Here at the Vespasian-Carlton, it’s just one
religious activity after another; the sky
is constantly being crossed by cruciform
airplanes, in which nobody disbelieves
for a second, and the tide, the tide
of spiritual progress and prosperity
miraculously keeps rising to a level
never before obtained. The churches are full,
the beaches are full, God’s great ocean is full
of paid vacationers praying an eight-hour day
to the human and spiritual values, the fruits,
the leisure, the energy, and the means, Lord,
the means for the level, the unprecedented level,
and the modern conveniences, which also are full.
Never before, O Lord, have the prayers and praises
from belfry, from phonebooth, from ballpark and barbecue
and sacrifices, so endlessly ascended.

It was not thus when Job in Palestine
sat in the dust and cried, cried bitterly;
when Damien kissed the lepers on their wounds
it was not thus; it was not thus
when Francis worked a fourteen-hour day
strictly for the birds; when Dante took
a week’s vacation without pay when it rained
part of the time, O Lord, it was not thus.

But now the gears mesh and the tires burn
and the ice chatters in the shaker and the priest
in the pulpit, and Thy Name, O Lord,
is kept before the public, while the fruits
ripen and religion booms and the level rises
and every modern convenience runneth over,
that it may never be with us as it hath been
with Athens and Karnak and Nagasaki,
nor Thy sun for one instant refrain from shining
on the rainbow Buick by the breezeway
or the Chris Craft with the uplift life raft;
that we may continue to be the just folk we are,
plain people with ordinary superliners, people of the stop’n’shop
‘n’ pray as you go, of hotel, motel, boatel,
the humble pilgrims of no deposit no return
and please adjust thy clothing, who will give to Thee,
if Thee will keep us going, our annual
Miss Universe, for Thy Name’s Sake, Amen.

by Howard Nemerov
from The American Experience: Poetry
Macmillen Company, 1968

Elias Rodriques at The Nation:

In the 1960s, the Free Southern Theater, an organization founded by a group of activists with the Student Nonviolent Coordinating Committee (SNCC), traveled to a church in a predominantly Black, rural corner of Mississippi. There they staged Samuel Beckett’s Waiting for Godot, an absurdist drama about characters conversing as they wait for someone who never arrives. The play may have seemed like a strange choice—who would imagine that Beckett might connect with rural Black Americans in the throes of the civil rights movement?—but it found at least one admirer in civil rights leader Fannie Lou Hamer. “I guess we know something about waiting, don’t we?” Hamer said from the audience.

more here.

Daniel Levin Becker at The Paris Review:

With apologies to Tolstoy, all perfect rhymes are alike, each imperfect rhyme imperfect in its own way. Perfect rhyme tells us about a relationship between words that never changes; that scoring with boring is a rhyme you can find in a dictionary is useful but also, not to put too fine a point on it, boring. But rhyming family with body—that’s interesting. How does she do it? Why does she do it? Imperfect rhyme—slant rhyme, off-rhyme, near-rhyme, half-rhyme, lazy rhyme, deferred rhyme, overzealous compound rhyme, corrugated rhyme, what have you—illuminates something about the person creating it, about their ear and their mind and what they’re willing to bend for the sake of sound. It tells us what they believe they can get away with through sheer force of will, like how Fabolous rhymes Beamer Benz or Bentley with team be spending centuries and penis evidently just because he knows he can.

more here.

Erika Page in The Christian Science Monitor:

Israel is often seen as a place of intractable divisions. But author Ethan Michaeli, the son of Israelis who moved to the United States, grew weary of hearing the same old narratives. So he set out on a journey to paint a more nuanced portrait. In “Twelve Tribes: Promise and Peril in the New Israel,” he brings readers along for the ride, introducing them to the complexities – and humanity – of life in modern Israel. A deeper understanding won’t fix everything, he says, but it may help uplift the debate. He spoke recently with the Monitor.

Why did you decide to write this book?

Whenever I see conversation among Americans about Israel, there’s no lack of care, there’s no lack of concern, there’s no lack of interest. But there’s a lack of currency. People are often arguing about things that in Israel are either not problems anymore or are problems that have multiplied twentyfold. So I thought that Israel is a very dynamic, very rapidly changing society, and a grassroots portrait of the country was necessary to really inform the conversation about it.

More here.

From Nature:

“We’ve known for many years that there is tumour-related material in the blood stream,” says Minetta C. Liu. “We just didn’t have the technologies to detect it with enough sensitivity for it to be meaningful.”

Liu, a medical oncologist and cancer investigator at the Mayo Clinic in Rochester, Minnesota, is one of a growing number of researchers advancing liquid biopsies as tools to understand cancer biology. The analyses of biomarkers in body fluids offers a minimally invasive and easily repeatable way to detect cancer-associated changes in the genome, epigenome, transcriptome and proteome. The wealth of information that can be obtained from material in blood and urine is opening new avenues for both research and disease monitoring.

In recent years, investigators have greatly improved the detection of many cancer biomarkers in liquid biopsies. Tests based on these biomarkers could, one day, do more than simply identify the presence of a tumour. They could help identify its location, stage, progression, and response to therapies, representing a paradigm shift in cancer diagnosis and management.

In research, the saying goes, extraordinary claims require extraordinary evidence. Where are those working on liquid biopsies placing their focus?

More here.

Annie Dillard in Literary Hub:

To comfort friends discouraged by their writing pace, you could offer them this:

It takes years to write a book—between two and ten years. Less is so rare as to be statistically insignificant. One American writer has written a dozen major books over six decades. He wrote one of those books, a perfect novel, in three months. He speaks of it, still, with awe, almost whispering. Who wants to offend the spirit that hands out such books?

Faulkner wrote As I Lay Dying in six weeks; he claimed he knocked it off in his spare time from a twelve-hour-a-day job performing manual labor. There are other examples from other continents and centuries, just as albinos, assassins, saints, big people, and little people show up from time to time in large populations. Out of a human population on earth of four and a half billion, perhaps twenty people can write a serious book in a year. Some people lift cars, too. Some people enter week-long sled-dog races, go over Niagara Falls in barrels, fly planes through the Arc de Triomphe. Some people feel no pain in childbirth. Some people eat cars. There is no call to take human extremes as norms.

More here.

Martha C. Nussbaum in Liberties:

Human beings, unlike all the other animals, hate animal bodies, especially their own. Not all human beings, not all the time. Leopold Bloom, pleased by the taste of urine, and, later, by the smell of his own shit rising up to his nostrils in the outhouse (“He read on, pleased by his own rising smell”), is a rare and significant exception, to whom I shall return. But most people’s daily lives are dominated by arts of concealing embodiment and its signs. The first of those disguises is, of course, clothing. But also deodorant, mouthwash, nose-hair clipping, waxing, perfume, dieting, cosmetic surgery — the list goes on and on. In 1732, in his poem “The Lady’s Dressing Room,” Jonathan Swift imagines a lover who believes his beloved to be some sort of angelic sprite, above mere bodily things. Now he is allowed into her empty boudoir. There he discovers all sorts of disgusting remnants: sweaty laundry; combs containing “A paste of composition rare, Sweat, dandruff, powder, lead, and hair”; a basin containing “the scrapings of her teeth and gums”; towels soiled with dirt, sweat, and earwax; snotty handkerchiefs; stockings exuding the perfume of “stinking toes”; tweezers to remove chin-hairs; and at last underwear bearing the unmistakable marks and smells of excrement. “Disgusted Strephon stole away/Repeating in his amorous fits,/Oh! Celia, Ceila, Celia shits!”

More here.

Raina MacIntyre in The Saturday Paper:

Denial of Omicron being serious suits an exhausted community who just wish life could go back to 2019. Omicron may be half as deadly as Delta, but Delta was twice as deadly as the 2020 virus. Importantly, the WHO assesses the risk of Omicron as high and reiterates that adequate data on severity in unvaccinated people is not yet available. Even if hospitalisation, admissions to intensive care and death rates are half that of Delta, daily case numbers are 20-30 times higher – and projected to get to 200 times higher. A tsunami of cases will result in large hospitalisation numbers. It is already overwhelming health systems, which common colds and seasonal flu don’t. Nor do they result in ambulance wait times of hours for life-threatening conditions. In addition, a tsunami of absenteeism in the workplace will worsen current shortages, supply chain disruptions and even critical infrastructure such as power. The ACTU has called for an urgent raft of measures to address the workforce crisis.

More here.  [Thanks to Den Rob.]

Eric Dean Wilson in The Baffler:

Before arriving in Glasgow, the phrase I heard most in connection with the twenty-sixth Conference of the Parties for the United Nations Framework Convention on Climate Change (COP26) wasn’t “just transition” or “sustainability” or “resilience.” It wasn’t “carbon capture and storage” or “green hydrogen” or “renewable energy.” It was “shitshow.” Par exemple: “COP 26 is going to be a shitshow.”

I heard this from friends, activists, university colleagues. Everyone agreed that COP26 would be some kind of performance, the needle on the end of delusion. Greta Thunberg put it best in a speech she delivered one month before the conference at the Youth4Climate summit in Milan: “Green economy blah blah blah, net zero by 2050 blah blah blah . . . climate neutral blah blah blah . . . Our hopes and dreams drown in their empty words and promises.” Only nonsense named the truth of what would take place. Of what wouldn’t take place.

More here.

Elaine Godfrey in The Atlantic:

FLORENCE, Ariz.—Tonight, deep in the Arizona desert, thousands of people chanted for Donald Trump. They had braved the wind for hours—some waited the entire day—just to get a glimpse of the defeated former president. And when he finally appeared on stage, as Lee Greenwood played from the loudspeakers, the crowd roared as though Trump were still the commander-in-chief. To many of them, he is. “I ran twice and we won twice,” Trump told his fans. “This crowd is a massive symbol of what took place, because people are hungry for the truth. They want their country back.”

Tonight’s rally was Trump’s first public event since July. On paper, the gathering was meant as his response to the anniversary of January 6, as well as an unofficial kickoff for his efforts to support Republicans in the midterm elections. But the event also served as the soft launch of Trump’s 2024 presidential campaign. Although he didn’t say the words, the former president seems poised to run in two years—”Make America Great Again Again … Again,” he joked to the crowd—and tonight, his message was as clear as it was dishonest: He didn’t lose to Joe Biden in 2020, and he’ll spend the next year working to elect Republicans who agree.

More here.

Lying in a Hammock at William Duffy’s Farm
in Pine Island, Minnesota

Over my head, I see a bronze butterfly,
Asleep on the black trunk,
Blowing like a leaf in green shadow.
Down the ravine behind the empty house,
The cowbells follow one another
Into the distances of the afternoon.
To my right,
In a field of sunlight between two pines,
The droppings of last year’s horses
Blaze up into golden stones.
I lean back, as the evening darkens and comes on.
A chicken hawk floats over, looking for home.
I have wasted my life.

by James Wright
from The Seashell Anthology
Random House, 1996

From The Paris Review:

On Wednesday, in the hours after Ronnie Spector’s family announced her passing from cancer at seventy-eight, I played, on loop, her cover of the Johnny Thunders punk anthem “You Can’t Put Your Arms Around a Memory.” Recorded for The Last of the Rock Stars, her 2006 comeback album, the song is also a dirge for Thunders, who died in 1991; he had been one of Ronnie’s crucial supporters in the period after she left her abusive ex-husband, the megalomaniac, murderer, and iconoclastic music producer Phil Spector. On YouTube, you can watch her perform a live version of the song from 2018: after showing footage from an archival interview the Ronettes did with Dick Clark sometime in the sixties, she comes out, to applause, and says, “Sorry, I was backstage crying.” Dabbing her eyes, she mourns the breakup of her iconic girl group, which also featured her older sister, Estelle, and cousin Nedra. “I thought 1966 was the end, no more Ronettes, no more stage, no more singing. I was out here in California and out of show business for seven or eight years. Let me tell you, life was a bitch.” She then describes starting over back in New York City in the ‘70s (she was raised in Spanish Harlem), and meeting Thunders while singing at the legendary gay club and bathhouse Continental Baths, where he cried all through her set. Later, she also met Joey Ramone, who produced an EP of hers and whose contributions to The Last of the Rock Stars include backing vocals on “You Can’t Put Your Arms Around a Memory.”

On the haunting track, Ronnie’s voice, its teen-dream girlishness scratched with nicotine, bears witness to the time that’s passed.

More here.