Surgeons Transplant 3-D-Printed Ear Made From Patient’s Own Cells

Roni Rabin in The New York Times:

A 20-year-old woman who was born with a small and misshapen right ear has received a 3-D printed ear implant made from her own cells, the manufacturer announced on Thursday. Independent experts said that the transplant, part of the first clinical trial of a successful medical application of this technology, was a stunning advance in the field of tissue engineering.

The new ear was printed in a shape that precisely matched the woman’s left ear, according to 3DBio Therapeutics, a regenerative medicine company based in Queens. The new ear, transplanted in March, will continue to regenerate cartilage tissue, giving it the look and feel of a natural ear, the company said. “It’s definitely a big deal,” said Adam Feinberg, a professor of biomedical engineering and materials science and engineering at Carnegie Mellon University. Dr. Feinberg, who is not affiliated with 3DBio, is a co-founder of FluidForm, a regenerative medicine company that also uses 3-D printing. “It shows this technology is not an ‘if’ anymore, but a ‘when,’” he said.

More here.

Friday Poem

My Front Yard, Summer (1941)

i wish you could see what i see out the window¹—rhododendron bush dropping blooms across the driveway & the bees drunk on fuchsia—stand of douglas firs thin as moon or fingernail or fingernail of moon, red cedars chartreuse-tipped behind them—& in the branches a goldfinch glittering, a squirrel sleeping rounded as the spots on the northern flicker’s breast—roof of the mailboxes felted with moss—purpleblue mountains against the grey eyelid of sky and no sun for miles, only the light filtered through the stratus—hill of ivy emerald and bright & in it the bugs and the dark dirt & the slug ripe and yellow— humming bush of salvia budding dusk-blue—& the earth a brittle throat of grass or a green tongue of huckleberry—the feeling of enormity in each thing—it is a very beautiful world. ²

by Clair Dunlap
from
The Ecotheo Review

¹ Georgia O’Keeffe to Arthur Dove, 1942
² Ibid

Reading Ourselves to Death

Kit Wilson at The New Atlantis:

Between 1900 and 1990, the amount of time the average American spent reading and writing remained broadly consistent: somewhere between one and two hours a day. According to a 2012 McKinsey report, the addition of text messaging and the Internet raised that amount to something closer to four or five hours a day. Most people were illiterate four hundred years ago; today Americans spend up to a third of their waking hours encoding and decoding text.

Every minute, humans send 220 million emails, 70 million WhatsApp and Facebook messages, 16 million texts, 530,000 tweets, and make 6 million Google searches. The journalist Nick Bilton has estimated that each day the average Internet user now sees as many as 490,000 words — more than War and Peace. If an alien landed on Earth today, it might assume that reading and writing are our species’ main function, second only to sleeping and well ahead of eating and reproducing.

more here.

China Miéville And The Communist Manifesto

Gavin Jacobson at The New Statesman:

What, I asked Miéville, might a counter-factual history of Marxism-communism look like if instead of “spectre” the opening had always included “hobgoblin”? “The serious answer,” he replied, “is that nothing would have changed. But the hobgoblin is a stranger figure than the ghost. What has always inspired me is the ‘red sublime’ – the unsayable, the beyond-speech, the apophatic; literally unthinkable change. I want a radical movement that understands that there is no ‘right’ way to do things. Maybe the hobgoblin is closer to the sublime than the spectre.” There are few outside academia who are better qualified to write on the Manifesto than Miéville. As a novelist, he is receptive to the “thunderously uncynical” style and expression of its authors – the declamatory tenor through which Marx and Engels literally willed the future. There is also the remarkable shift in voice into the second person, when the Manifesto goes from discussing the bourgeoisie to excoriating it directly, “You reproach us [communists] with intending to do away with your property. Precisely so; that is just what we intend.”

more here.

Thursday, June 23, 2022

Thought experiments played a crucial role in the history of science. But do they tell us anything about the real world?

Dan Falk at Aeon:

In Galileo’s Dialogue Concerning the Two Chief World Systems (1632), three Italian gentlemen – one philosopher and two laymen – debate the structure of the Universe. The philosopher, Salviati, argues in support of the Copernican theory, even though it requires a moving Earth – something that strikes his interlocutors as problematic, if not absurd. After all, we don’t feel the ground moving beneath our feet; clouds and birds are not swept backwards as the planet whooshes through space; a ball dropped from a tower does not land far away from the base of that tower.

But Salviati, standing in for Galileo, asks his companions, Sagredo and Simplicio, to reconsider their intuitions. Suppose one were to drop an object from the mast of a tall ship. Does it make any difference if the ship is moving? No, Salviati insists; it lands at the base of the mast regardless, and therefore one cannot conclude anything at all about the ship’s motion from such an experiment. If the ship can be in motion, then why not the whole planet? Simplicio objects: Salviati has not actually carried out this shipboard experiment, so how can he be sure of the result?

More here.

The European space mission that plans to ambush a comet

Jonathan O’Callaghan in Nature:

The European Space Agency (ESA) has approved a new mission, called Comet Interceptor, which will launch without any specific target in mind — instead lying in wait for a visitor from the outer Solar System, or even from another star. Comet Interceptor could give researchers a first glimpse of pristine material from far beyond the Sun’s reaches, or even unveil the chemical make-up of alien worlds.

It will be the first probe to be parked in space, ready to fly to a target at short notice. “We are taking a significant risk,” says Günther Hasinger, ESA’s director of science. “But it’s a high reward.”

The mission, first put forward in 2019, will launch in 2028 along with a new telescope, Ariel, designed to study the atmospheres of exoplanets.

More here.

How did Brexit do so much damage in so short a time?

Jonathan Lis in Prospect:

T4MRKE 28th February 2018 – Michelle Mary O’Neill is an Irish politician who has served as Vice President of Sinn FA©in since February 2018, and Leader of S

We don’t even have to cast our minds back to the EU referendum. Imagine for a moment that a vote was being proposed today. In the wake of the pandemic, in the middle of a cost of living crisis, and during a war in Europe that demands unity and solidarity across the continent—how would the British public respond to a political party that proposed Brexit? The idea of splitting the UK from its European neighbours would be seen as indulgent or preposterous—self-evidently absurd.

But of course the case against Brexit does not need to rely on counterfactuals. We can look at the real world, in which the project is failing on every discernible level.

More here.

Neither Chaos Nor Quest: Toward a Nonnarrative Medicine

Brian Teare in The Boston Review:

In Arthur W. Frank’s foundational text for narrative medicine, The Wounded Storyteller: Body, Illness, and Ethics (1995), the ill, Frank suggests, need “to tell their stories, in order to construct new maps and new perceptions of their relationships to the world.” Frank posits three common narrative structures for the experience of illness: restitution, chaos, and quest. In restitution narratives, the healthy person becomes sick and then they become healthy again, a quick, clean plot that reifies health in ways too naïve to be meaningful. This, of course, is the arc popular culture prefers.

In chaos narratives, the unlucky ill suffer without plot, their nonnarratives untouched by restitution or even just movement toward suffering in a more agentive way. Frank seems genuinely freaked out by so-called chaos. In his account, chaos strains the limits of caregiver empathy and institutional capacity because the chaotic body is nonnarrative—which, for Frank, is in effect to be a non-self, one who cannot effectively communicate or connect with others.

In quest narratives, the plot Frank prefers, the ill person finds the strength and agency to turn their experience of illness into allegory, a journey of insight gained from suffering. As opposed to the pro forma performances of restitution and the nonnarratives of chaos, quest narratives feature a “communicative body” that models for others that patients can “accept illness and seek to use it.” So central is this narrative structure to Frank’s conception of illness that he claims, “Becoming seriously ill is a call for stories.”

Is it, though? What if serious illness doesn’t or can’t call for anything? Or if it can, it’s only the body’s call for the restoration of equilibrium?

More here.

Why Casanova Continues to Seduce Us

Judith Thurman in The New Yorker:

In 1763, the young James Boswell finished his “London Journal,” one of the frankest accounts of high and low life in the eighteenth century. The following year, he embarked on a Grand Tour. In a Berlin tavern, he encountered a certain Neuhaus. This voluble personage of thirty-nine, unusually tall, with a dark complexion and affected manners, was an Italian who “wanted to shine as a great philosopher,” Boswell wrote, “and accordingly doubted of his own existence and everything else. I thought him a blockhead.”

The “blockhead” had also been travelling around Europe, although not on a patrician’s leisurely inspection of art and ruins. Giacomo Casanova, whose surname means “new house,” practiced many trades—violinist, gambler, spy, Kabbalist, soldier, man of letters—but his main line of work, he later admitted, was deceiving fools. Many of them were gulls at a card table, though he had recently convinced an elderly marquise, a widow with a vast fortune and an obsession with the occult, that he could arrange for her rebirth as her own son. How would this work? Casanova’s mystically enabled sperm would impregnate her with a male fetus endowed with her soul. A casket of jewels was involved, along with a comely young accomplice posing as a naked water nymph. When his ardor flagged, the nymph’s task was to rekindle it.

Casanova had a sideline, of course, which has earned him eponymous immortality; most of us, I’d venture to say, have met “a real Casanova.” But his conquests in the boudoir, not to mention those in carriages, in bathhouses, or behind park shrubbery, have eclipsed his accomplishments while fully dressed. He translated the Iliad into Italian; he published a utopian novel; he grappled with problems in classical geometry; he traded bons mots with Voltaire. He even charmed his way into the French court, posing as a financier, and sold Louis XV on the concept of a national lottery.

More here.

Thursday Poem

Genesis. Around the Eighth Chapter

on the ark noah lodges stegosaurs tyrannosaurs plesiosaurs
brontosaurs archaeopteryxes iguanodons diplodocuses triceratops
they are small and smiley-faced
they will all fit
everyone will sail off peacefully

it’s a long journey

a snow-white pterodactyl
flies out of the ark
and returns bearing a green branch in its mouth
so the banks of hollywood must be nearby
so everyone’s been saved for some reason

god hanging on to the branch for dear life
squeaks like a toy in the jaws of a puppy

by Andrej Sen-Senkov
from International Poetry Web

In Search of Strangeness

Anthony Domestico at Commonweal:

We’ll start with a pair of shoes. In 1944, a young Italian woman named Emilia “Ilia” Terzulli marries an older English soldier named Esmond Warner. They’re an unlikely couple. Nicknamed “La Giraffa,” Ilia is tall, poor, gorgeous, and untraveled. Esmond is balding, bespectacled, and worldly. She’s not just Italian but southern Italian; he’s not just English but English English, his family’s wealth faded but not their lordly idiosyncrasies. (His mum goes by Mother Rat; his father, a former professional cricketer, by Plum; his childhood pet rat by Scoot.) And so, to make his Bari-born wife feel at home in South Kensington, Esmond buys Ilia a pair of shoes. More specifically, he buys her “bespoke brogues”: sturdy, plain-ish, yet expensive shoes that mark Ilia’s “formal enrolment in the world of the squirearchy, hunting, going to the point-to-point, the harriers, the beagles, the open-gardens scheme, the charity fête.”

We read about these brogues in Marina Warner’s Esmond and Ilia: An Unreliable Memoir (New York Review Books, 432 pp., $19.95).

more here.

‘A Sultry Month’ by Alethea Hayter

Lucy Scholes at The Paris Review:

One hundred and seventy-six years ago today, on the evening of Monday, June 22, 1846, the painter Benjamin Robert Haydon—sixty years old and facing imminent financial ruin—locked himself in his studio in his house on Burwood Place, just off London’s Edgware Road. The month had been the hottest anyone could remember: that day, thermometers in the city stood at ninety degrees in the shade. Despite the heat, that morning Haydon had walked to a gunmaker’s on nearby Oxford Street and purchased a pistol. He spent the rest of the day at home, composing letters and writing a comprehensive, nineteen-clause will.

That evening, only a few streets away in Marylebone, Elizabeth Barrett penned a letter to her fiancé, Robert Browning. The poets’ courtship was still a secret, but they wrote each other constantly, sometimes twice a day. Like everyone else, Elizabeth was exhausted by the weather; earlier in the month she had complained to Browning that she could do nothing but lie on her sofa, drink lemonade, and read Monte Cristo.

more here.

Wednesday, June 22, 2022

Stewart Brand’s Dubious Futurism

Malcolm Harris in The Nation:

Stewart Brand is not a scientist. He’s not an artist, an engineer, or a programmer. Nor is he much of a writer or editor, though as the creator of the Whole Earth Catalog, that’s what he’s best known for. Brand, 83, is a huckster—one of the great hucksters in a time and place full of them. Over the course of his long life, Brand’s salesmanship has been so outstanding that scholars of the American 20th century have secured his place as a historical figure, picking out the blond son of Stanford from among his peers and seating him with inventors, activists, and politicians at the table of men to be remembered. But remembered for what, exactly?

Whole Earth: The Many Lives of Stewart Brand is the first full biographical consideration of a man who has already provided useful fodder for writers seeking to characterize the various social and intellectual movements that came out of California in the final third of the 20th century.

More here.

Sean Carroll’s Mindscape Podcast: Ed Yong on How Animals Sense the World

Sean Carroll in Preposterous Universe:

All of us construct models of the world, and update them on the basis of evidence brought to us by our senses. Scientists try to be more rigorous about it, but we all do it. It’s natural that this process will depend on what form that sensory input takes. We know that animals, for example, are typically better or worse than humans at sight, hearing, and so on. And as Ed Yong points out in his new book, it goes far beyond that, as many animals use completely different sensory modalities, from echolocation to direct sensing of electric fields. We talk about what those different capabilities might mean for the animal’s-eye (and -ear, etc.) view of the world.

More here.

Mechanization and Monoculture

Alan Jacobs in The Hedgehog Review:

Near the end of his brilliant memoir Tristes Tropiques, anthropologist Claude Levi-Strauss describes his visits to various rum distilleries in the Caribbean:

In Martinique, I had visited rustic and neglected rum-distilleries where the equipment and the methods used had not changed since the eighteenth century. In Puerto Rico, on the other hand, in the factories of the company which enjoys a virtual monopoly over the whole of the sugar production, I was faced by a display of white enamel tanks and chromium piping. Yet the various kinds of Martinique rum, as I tasted them in front of ancient wooden vats thickly encrusted with waste matter, were mellow and scented, whereas those of Puerto Rico are coarse and harsh.

Meditation on this contrast leads Levi-Strauss to a more general insight:

We may suppose, then, that the subtlety of the Martinique rums is dependent on impurities the continuance of which is encouraged by the archaic method of production. To me, this contrast illustrates the paradox of civilization: Its charms are due essentially to the various residues it carries along with it, although this does not absolve us of the obligation to purify the stream. By being doubly in the right, we are admitting our mistake. We are right to be rational and to try to increase our production and so keep manufacturing costs down. But we are also right to cherish those very imperfections we are endeavouring to eliminate. Social life consists in destroying that which gives it its savour.

A melancholy reflection, to be sure—but perhaps not an inevitable one.

More here.

‘Thrust’ delivers a mind-blowing critique of America’s ideals

Ron Charles in The Washington Post:

Lidia Yuknavitch’s extraordinary new novel is the weirdest, most mind-blowing book about America I’ve ever inhaled. Part history, part prophecy, all fever dream, “Thrust” offers a radical critique of the foundational ideals that conceal our persistent national crimes. As we march from Juneteenth to July 4, this is a story to scrub the patinated surface of our civic pride.

There’s a tidal movement to “Thrust,” whose chapters ebb and flow across 200 years in and around the New York Harbor. At the opening, we catch a vision of immigrants working on a colossal new monument designed in France and shipped in pieces to the United States. With allusions to Walt Whitman, Yuknavitch gives voice to the multitude. “We were woodworkers, iron workers, roofers and plasterers and brick masons,” the narrator intones. “We were pipe fitters and welders and carpenters … We were cooks and cleaners and nuns and night watchpeople. We were nurses and artists and janitors, runners and messengers and thieves. Mothers and fathers and grandparents, sisters and brothers and children.”They are, in short, the whole panoply of fresh Americans drawn here from around the planet, and they’re pounding 31 tons of copper and 125 tons of steel into a towering statue of a robed woman holding a torch aloft to light the way to liberty.

More here.