From SciTechDaily:
To learn to socialize, zebrafish need to trust their gut. Gut microbes encourage specialized cells to prune back extra connections in brain circuits that control social behavior, new University of Oregon research in zebrafish shows. The pruning is essential for the development of normal social behavior.
The researchers also found that these ‘social’ neurons are similar in zebrafish and mice. That suggests the findings might translate between species — and could possibly point the way to treatments for a range of neurodevelopmental conditions. “This is a big step forward,” said University of Oregon neuroscientist Judith Eisen, who co-led the work with neuroscientist Philip Washbourne. “It also sheds light on things that are going on in larger, furrier animals.” The team reports their findings in two new papers, published in PLOS Biology and BMC Genomics.
While social behavior is a complex phenomenon involving many parts of the brain, Washbourne’s lab previously identified a set of neurons in the zebrafish brain that are required for one particular kind of social interaction. Normally, if two zebrafish see each other through a glass partition, they’ll approach each other and swim side by side. But zebrafish without these neurons don’t show interest. Here, the team found a pathway linking microbes in the gut to these neurons in the brain. In healthy fish, gut microbes spurred cells called microglia to prune back extra links between neurons.

Each of us constructs and lives a “narrative”,’ wrote the British neurologist Oliver Sacks, ‘this narrative is us’. Likewise the American cognitive psychologist Jerome Bruner: ‘Self is a perpetually rewritten story.’ And: ‘In the end, we become the autobiographical narratives by which we “tell about” our lives.’ Or a fellow American psychologist, Dan P McAdams: ‘We are all storytellers, and we are the stories we tell.’ And here’s the American moral philosopher J David Velleman: ‘We invent ourselves… but we really are the characters we invent.’ And, for good measure, another American philosopher, Daniel Dennett: ‘we are all virtuoso novelists, who find ourselves engaged in all sorts of behaviour… and we always put the best “faces” on it we can. We try to make all of our material cohere into a single good story. And that story is our autobiography. The chief fictional character at the centre of that autobiography is one’s self.’
What do Noam Chomsky, living legend of linguistics, Kai-Fu Lee, perhaps the most famous AI researcher in all of China, and Yejin Choi, the 2022 MacArthur Fellowship winner who was profiled earlier this week in The New York Times Magazine—and more than a dozen other scientists, economists, researchers, and elected officials—all have in common?
The problems created by humanity’s dependence on fossil fuels are widely appreciated, and governments and businesses are now pursuing renewable energy and electric vehicles as the solution. Less appreciated is that this new infrastructure will require the mining of vast amounts of metals, creating different problems. In Volt Rush, Financial Times journalist Henry Sanderson gives a well-rounded and thought-provoking exposé of the companies and characters behind the supply chain of foremost the batteries that will power the vehicles of the future. If you think a greener and cleaner world awaits us, Volt Rush makes it clear that this is far from a given.
I really enjoy doing it: it makes me feel good about myself. It gives me a boost, mentally and physically.” If these were your reactions to an activity, you’d surely be inclined to do it as often as you could. After all, aren’t a lot of us looking for ways to find more meaning in life and to be happier and healthier? What, then, is the act that elicits such positive responses? The answer: being
S
In recent years, the vagus nerve has become an object of fascination, especially on social media. The vagal nerve fibers, which run from the brain to the abdomen, have been anointed by some influencers as the key to reducing anxiety, regulating the nervous system and helping the body to relax.
Alex Turnbull in Phenomenal World:
Marco D’Eramo in Sidecar:
David Kurnick in Bookforum:
Paul Grimstad in The Baffler:
On August 11th an unemployed 42-year-old grabbed his shotgun and a large jerry can of petrol. Dressed in a T-shirt and flip-flops, Bassam al-Sheikh Hussein walked into a
Bushra Rehman’s stunningly beautiful coming-of-age novel “Roses, in the Mouth of a Lion” is set in the Corona neighborhood of Queens, New York, which was enshrined in pop culture by Paul Simon’s 1972 hit “Me and Julio Down by the Schoolyard.” Rehman’s exuberant young protagonist, Razia, knows the song well, although it puzzles her. “Why would Paul Simon be singing about Corona?” she muses. “I didn’t see many white people there unless they were policemen or firemen, and I didn’t think Paul Simon had ever been one of those.”
I
Failure, as Costica Bradatan puts it in his bracing new book, is good for you, but not for the reasons you might think. “In Praise of Failure” is maddening, disturbing, exasperating, seductive — I found myself turned around at so many points that even as I was closing in on the last chapter I wasn’t quite sure where I would land at the end.