Laith Al-Shawaf at Areo:

If you infect a rabbit with a virus or a bacterium, it’ll start to run a fever. Why? The surprising answer is that fever is not a disease; it’s a defence: a useful evolved mechanism that animals use to kill invading pathogens. Studies show that if you give fever-suppressing drugs to infected rabbits, they’re more likely to die.

It’s not just rabbits—all warm-blooded creatures use fever to kill invasive parasites. Animals that can’t regulate their body temperature internally take a different approach. For example, infected lizards seek a hot rock on which to sunbathe, raising their body temperature and killing the invaders that way—and research shows that disrupting their ability to do this increases their likelihood of death. Infected fish and reptiles exhibit this kind of “behavioural fever,” too. In humans, some studies find that administering fever-suppressing drugs to children may worsen outcomes and prolong the period of illness.

These findings suggest that fever is not a symptom of a disease; it’s an evolved defence that our bodies use to kill harmful invaders. Discoveries like this represent one small part of a larger picture emerging from the new science of evolutionary medicine. There’s a scientific revolution brewing, catalysed by the idea that considering how our bodies evolved will help us better understand and treat disease.

More here.

Moeen Farrokhi at Literary Hub:

I have never told this story in its entirety to anyone: not to my therapist, not to my closest friends, and not even to my family. I’ve divulged bits and pieces of it to different people. When my friends back home in Iran asked me why I was leaving, I made up a thousand different reasons. When my friends in Istanbul asked me what happened and why I came, I said that a part of me had died, that my ambition, courage, and hope for the future had dried up. But I didn’t explain why. I couldn’t connect the single moments into a coherent narrative.

More here.

Sarah Nicole Prickett at Bookforum:

WHEN A DEER, A DOE, STEPPED INTO THE ROAD perhaps a hundred and twenty feet ahead of the car I was driving, it seemed for a moment that she would die, even though, during the same moment, I did not feel afraid that I would hit her. I was calm; I returned my smoking hand to the steering wheel; I braked. The deer seemed to be looking at me. There was a chance she might actually run toward me. I switched off the high-beams. All of this happened in two and a half seconds, before the deer continued across the road, safely to the other side, in a single bound. It was then that, exhaling, I realized the extent to which I had felt for—on behalf of—the animal, and for days after I dwelled on the feeling.

Why, in my memory of the moment, was my thought so precisely that the deer would die? Without being afraid, I had made a leap. I had ascribed to her something like a death wish, or, in more properly psychoanalytic terms, a death instinct.

more here.

Barbara Spindel in The Christian Science Monitor:

Drew Gilpin Faust’s memoir is both a moving personal narrative and an enlightening account of the transformative political and social forces that impacted her as she came of age in the 1950s and ’60s. It’s an apt combination from an acclaimed historian who’s also a powerful storyteller.

“Necessary Trouble: Growing Up at Midcentury” describes Dr. Faust’s upbringing as a privileged white girl in segregated Virginia, where she chafed at constraints placed on her because of her gender and was outraged by the racial discrimination she saw around her. (The book opens with a copy of her handwritten letter to President Dwight Eisenhower, penned at age 9, asking him to end school segregation.)

By the time “Necessary Trouble” concludes in 1968, with Dr. Faust’s graduation from Bryn Mawr College, she had rejected the culture in which she was raised, embracing the civil rights and anti-war movements and daring to imagine a different future for herself. She went on to become a scholar of the American South and, later, the first woman president of Harvard University, a position she held from 2007 to 2018. She recently spoke with the Monitor.

More here.

Mitch Leslie in Science:

When the diabetes treatments known as GLP-1 analogs reached the market in 2005, doctors advised patients taking the drugs that they might lose a small amount of weight. Talk about an understatement. Obese people can drop more than 15% of their body weight, studies have found, and two of the medications are now approved by the U.S. Food and Drug Administration (FDA) for weight reduction. A surge in demand for the drugs as slimming treatments has led to shortages. “This class of drugs is exploding in popularity,” says clinical psychologist Joseph Schacht of the University of Colorado School of Medicine.

But patient reports and animal studies have yielded tantalizing signs that the drugs may spur another unexpected and welcome effect: fighting addiction. Most early trials were disappointing, but they used less potent versions of the drugs. Now, at least nine phase 2 clinical trials are underway or being planned to test whether the more powerful compound semaglutide and its chemical cousins can help patients curb their use of cigarettes, alcohol, opioids, or cocaine. Hopes are high. Semaglutide (sold under the trade names Wegovy, Ozempic, and Rybelsus) “is truly the most exciting drug for the last few decades,” says neuropharmacologist Leandro Vendruscolo of the U.S. National Institute on Drug Abuse.

If the results of the new trials are positive, addiction science could have its own “Prozac moment,” says clinical neuroscientist W. Kyle Simmons of the Oklahoma State University Center for Health Sciences. In the 1980s, that drug brought a sea change to psychiatry, becoming part of popular culture and leading to the wider use of antidepressants.

More here.

Summer Day

Who made the world?
Who made the swan, and the black bear?
Who made the grasshopper?
This grasshopper, I mean—
the one who has flung herself out of the grass,
the one who is eating sugar out of my hand,
who is moving her jaws back and forth instead of up and down—
who is gazing around with her enormous and complicated eyes.
Now she lifts her pale forearms and thoroughly washes her face.
Now she snaps her wings open, and floats away.
I don’t know exactly what a prayer is.
I do know how to pay attention, how to fall down
into the grass, how to kneel down in the grass,
how to be idle and blessed, how to stroll through the fields,
which is what I have been doing all day.
Tell me, what else should I have done?
Doesn’t everything die at last, and too soon?
Tell me, what is it you plan to do
with your one wild and precious life?

by Mary Oliver
from Poetic Outlaws

Geoffrey Hiller at Saigoneer:

In 1995, there weren’t many foreign tourists in the country. It was a year after the United States normalized relations with Hanoi and lifted sanctions. Most of the passengers on the flight to Hồ Chí Minh City were Việt kiều, visiting their country for the first time since they left. The tension they felt as they cleared customs was obvious.

I stayed for close to a month and mainly traveled overland by train on the Reunification Express from Saigon to Hanoi. I stopped over for a few days each in Nha Trang, Đà Nẵng, Huế and Hanoi, and made overland trips to Đà Lạt and Hội An. Passing through the rice fields of Central Vietnam as the sun was rising felt like a dream; the landscape out the window had so many variations of the color green.

more here.

Dženana Vucic in the Sydney Review of Books:

In Germany they joke that Slavs live in poverty so they can drive home in a Mercedes. I hadn’t heard this stereotype growing up in so-called Australia. From there, we had to fly.

Bosnia is a long way away, and it’s an expensive journey. During my childhood, we only flew back once. I was eleven and I don’t remember much except my mother’s constant anxiety, her fear of landmines and strange men. Our migration to Australia had been an escape: from the genocidal war that had been waged against Bosnian Muslims between 1992 and 1995, and from its aftermath. Our return forced us to confront what we had left behind, what we had done in leaving everyone behind.

When I went back to Bosnia a second time, as an adult and alone, I stayed for three weeks. It wasn’t enough so I returned for six months, intending it to be forever. This is the kind of decision you can make at twenty-five. Impulsive, reckless.

More here.

Matthew Sparkes in New Scientist:

There is a global rush for GPU chips, the graphic processors that were originally designed to run video games and have also traditionally been used to train and run AI models, with demand outstripping supply. Studies have also shown that the energy use of AI is rapidly growing, rising 100-fold from 2012 to 2021, with most of that energy derived from fossil fuels. These issues have led to suggestions that the constantly increasing scale of AI models will soon reach an impasse.

Another problem with current AI hardware is that it must shuttle data back and forth from memory to processors in operations that cause significant bottlenecks. One solution to this is the analogue compute-in-memory (CiM) chip that performs calculations directly within its own memory, which IBM has now demonstrated at scale.

IBM’s device contains 35 million so-called phase-change memory cells – a form of CiM – that can be set to one of two states, like transistors in computer chips, but also to varying degrees between them.

More here.

Ville Lähde in Aeon:

Sometimes words explode. It is a safe bet that, before 2022, you had never even heard the term ‘polycrisis’. Now, there is a very good chance you have run into it; and, if you are engaged in environmental, economic or security issues, you most likely have – you might even have become frustrated with it. First virtually nobody was using polycrisis talk, and suddenly everyone seems to be.

But, as often happens, people seem to mean quite different things with the word. So, what does ‘polycrisis’ mean? The term reverberated at the United Nations Climate Change Conference (COP27) in Sharm El-Sheikh in November 2022, and in Davos the following January, as The New York Times noted. In the Financial Times, Jonathan Derbyshire chose it for his 2022 ‘Year in a Word’ piece, defining ‘polycrisis’ as a collective term for interlocking and simultaneous crises.

More here.

Pete Riehl in The Millions:

Hiding in plain sight, the largely unexamined crack epidemic of the 1980s and early 1990s has much to teach us about current US drug policy, the blatant racism of drug-related sentencing, and the power of community action. In his important, balanced book When Crack Was King: A People’s History of a Misunderstood Era, Donovan X. Ramsey takes a wide and necessary view of the choices—sinister and well-meaning alike—that led to the epidemic.  To complement his sweeping historical and political analysis, Ramsey also spends time with individual people who weathered the worst of the era and lived to share its lessons.

I spoke with Ramsey about the crack epidemic and what it can teach us about propaganda, criminalization, racist policing, and community care.

More here.

Cara Buckley in The New York Times:

The tiny forest lives atop an old landfill in the city of Cambridge, Mass. Though it is still a baby, it’s already acting quite a bit older than its actual age, which is just shy of 2. Its aspens are growing at twice the speed normally expected, with fragrant sumac and tulip trees racing to catch up. It has absorbed storm water without washing out, suppressed many weeds and stayed lush throughout last year’s drought. The little forest managed all this because of its enriched soil and density, and despite its diminutive size: 1,400 native shrubs and saplings, thriving in an area roughly the size of a basketball court.

It is part of a sweeping movement that is transforming dusty highway shoulders, parking lots, schoolyards and junkyards worldwide. Tiny forests have been planted across Europe, in Africa, throughout Asia and in South America, Russia and the Middle East. India has hundreds, and Japan, where it all began, has thousands. Now tiny forests are slowly but steadily appearing in the United States. In recent years, they’ve been planted alongside a corrections facility on the Yakama reservation in Washington, in Los Angeles’s Griffith Park and in Cambridge, where the forest is one of the first of its kind in the Northeast.

More here.

Melissa Koenig in The New York Post:

More here.

The Music Pool

You have to put your head in.
It’s so much like silence
it takes all your breath
to begin
hearing it. Then you never forget
the sound of being held
completely still by someone you love.
Soon you will undress
but not yet

by William Matthews
from Sleek for the Long Flight
White Pine Press,1988

Advait Arun in Phenomenal World:

The world urgently needs financing for renewable energy, infrastructure, public transit, land restoration, and much more to face the storm of climate change. But these necessary capital investments in the green transition face real barriers, such as a high cost of capital or slow land acquisition. Policymakers, their critics, and investors alike are right to worry about these financial and regulatory obstacles.

The pandemic, commodity price shocks, and US interest-rate hikes have left global South countries with limited fiscal room to invest in cutting emissions and building resilience against climate change. The upper crust of development policymakers believe that the best way to bridge this green finance gap is to incentivize deep-pocketed institutional investors:  a broad category that includes pension funds, investment banks, asset managers, insurers, and private equity funds. Assumed to collectively possess the capital that governments do not, they are meant to fund and operate the green infrastructure and services people need. In this view, the trillions of dollars per year needed this decade for climate adaptation and mitigation investments are trillions of dollars worth of new assets for investors.

Policymakers promote “mobilizing private finance” as a solution that mutually benefits common people and investors. Achieving this requires the state to shoulder the costs as well as the investment risks; this is the logic of financial derisking, which operates chiefly through loan guarantees, blended finance funds, securitization structures, and project preparation services. Critics argue that these forms of financial derisking socialize investors’ risks while allowing them to reap profits, accelerate the privatization of public goods across emerging markets, and place the private sector in the drivers’ seat of the green transition. But it’s unclear if investors can actually finance all the world’s unmet financing needs. Is it technically possible?

More here.