Amy Schleunes in The Scientist:
The first thing Martha Carlin noticed was a faraway look in her husband’s eyes. It was a subtle change, she says, something only a wife would see. She happened to be reading Lucky Man by Michael J. Fox at the time, and began to wonder about some of the symptoms she’d observed in her husband: his loss of facial expressions, his quivering pinky finger, his trembling tongue. An appointment with an internist led to an appointment with a neurologist, who confirmed Carlin’s worst fears. In the fall of 2002, her husband John was diagnosed with Parkinson’s disease. He was 44 years old.
Carlin spent the next seven years reading everything she could find on Parkinson’s. A consultant skilled at identifying breakpoints in businesses, Carlin concluded that the disease is “a systems problem,” she says, a collapse of the body’s ecosystem. Much of what she had learned implicated the gut, including the finding that constipation is one of the earliest symptoms of Parkinson’s, often emerging 10 years or more before a diagnosis. In late 2014, Carlin read a study that identified a specific imbalance in the composition of Parkinson’s patients’ gut microbiomes, suggesting that changes in the gut microbiota could be an important biomarker for the disease. “That is it,” she remembers thinking. “The gut is the general ledger of the body.”
She quit her consulting job and enlisted the help of Jack Gilbert, a microbiome expert then at the University of Chicago. Carlin paid Gilbert, who serves on The Scientist’s editorial advisory board, to analyze her and her husband’s stool samples, and also donated $30,000 to cover part of the salary of one of his postdocs. Together, she and Gilbert pored over the microbiome literature. They kept coming across mentions of certain microbial genes that were overexpressed in conditions such as Parkinson’s and autism, suggesting “functional similarities at a systems level,” Carlin says. It seemed logical to her that investigating such complex conditions would require looking at the whole community of bacteria in the living system.
More here.

The call to “defund the police” has
For vonny leclerc
The largest number of COVID-19 supercomputing projects involves designing drugs. It’s likely to take several effective drugs to treat the disease. Supercomputers allow researchers to take a rational approach and aim to selectively
Today marks the anniversary of the death of Robert F. Kennedy, assassinated in 1968 after winning the primary in California, on the way to obtaining the nomination of the Democratic party and, perhaps, the presidency.
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How does it feel to be black in America right now? First, I wonder, do I capitalize the “B”? Is that grammatically correct? More to the point, as an element of style, a choice, does it prove something to you or to me if I don’t? I confess I don’t know any more. These are the petty games that play on my mind as a black American. I cannot speak for all black people, of course. We are not a monolith; you seem to understand this by now. I can only speak for myself – as a black writer. That experience, at least, I know. Instead of worrying about the white man who might murder me in my own home, or on my morning run, what preys on me in the night is how I constructed the sentence as I replay the day, if it was adequately punctuated in its disavowal of racist oppression.
Mona Ali in The Political Quarterly:
James Baldwin in The New Yorker:
Andrew Hui in Aeon:
Quinn Slobodian in The Guardian:
Lara Putnam, Erica Chenoweth and Jeremy Pressman over at the Monkey Cage:
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Academic critics of Dryden or Pope were not in the habit, the last time I checked, of interspersing their monographs with reminiscences of sex clubs in Manhattan. An affectionate excursus on that subject in Mark Doty’s What is the Grass announces that this is no ordinary piece of literary criticism. ‘And your very flesh shall be a great poem,’ wrote Doty’s subject, Walt Whitman, who, one suspects, wouldn’t have minded a bit. Perhaps best known for his 1993 collection My Alexandria, prompted by the AIDS pandemic, Doty is one of the most compelling modern singers of ‘the body electric’ and in What is the Grass he has produced an elegant meditation on the great founding father of American poetry. Not only did Whitman’s example fire up the democratic modern lyrics of W C Williams and Allen Ginsberg; it also licensed poets to place themselves centre stage in their prose, from Adrienne Rich in What is Found There to Susan Howe in her prose-poetry hybrids. It is a licence that Doty seizes on greedily.