James Gallagher in BBC:
Relics of ancient viruses – that have spent millions of years hiding inside human DNA – help the body fight cancer, say scientists. The study by the Francis Crick Institute showed the dormant remnants of these old viruses are woken up when cancerous cells spiral out of control. This unintentionally helps the immune system target and attack the tumour. The team wants to harness the discovery to design vaccines that can boost cancer treatment, or even prevent it. The researchers had noticed a connection between better survival from lung cancer and a part of the immune system, called B-cells, clustering around tumours.
B-cells are the part of our body that manufactures antibodies and are better known for their role in fighting off infections, such as Covid. Precisely what they were doing in lung cancer was a mystery but a series of intricate experiments using samples from patients and animal tests showed they were still attempting to fight viruses. “It turned out that the antibodies are recognising remnants of what’s termed endogenous retroviruses,” Prof Julian Downward, an associate research director at the Francis Crick Institute, told me. Retroviruses have the nifty trick of slipping a copy of their genetic instructions inside our own.
More here.

Salman Rushdie
There is no guarantee that someone in the foreseeable future won’t develop dangerous autonomous AI systems with behaviors that deviate from human goals and values. The short and medium term risks –manipulation of public opinion for political purposes, especially through disinformation– are easy to predict, unlike the longer term risks –AI systems that are harmful despite the programmers’ objectives,– and I think it is important to study both.
This issue of Lapham’s Quarterly bravely addresses the hotly contested word freedom. It is hotly contested in part because what the word means has never been clear, a fact that has not seemed to lessen its importance for us. It is a word in which we have invested enormous amounts of energy without producing much in the way of illumination. And yet freedom cannot be dismissed simply on semantic grounds—“just another word,” as Kris Kristofferson sang—because what is at its heart may very well answer the question “What does it mean to be human?”
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Nowadays the title reads not only as tepid and banal but as distinctly unrepresentative of the ensuing narrative’s principal themes and contours. In fairness, when the onetime Austro-Hungarian actress and subsequently Hollywood scenarist Salka Viertel first began auditioning the phrase “the kindness of strangers” for the title of her memoir in progress, back in the mid-1950s, as her recent biographer Donna Rifkind has pointed out, the words were not nearly as hackneyed as they are today. (The sensational play A Streetcar Named Desire, from which they sprang, was only a few years old, having premiered in 1947; the film had only been released in 1951; and the primary chestnut to have emerged from the latter was Stanley’s bloodcurdling scream of “Stella! Stellllaaaa!” and not so much Blanche’s breathy Southern belle protestations of having always reliii-ed on the kindness of strangers.) Salka’s husband, the internationally acclaimed theater director Berthold Viertel, had been translating their friend Tennessee Williams’s plays for some years already and staging them all over Europe, and perhaps Salka savored the nod in the young playwright’s direction. Such selfless generosity, indeed such kindness on her own part, would have been just like her.
Walter was tall and gaunt with a hard-to-place, vaguely English accent. He favored Kools and Chardonnay, and he was never photographed in anything but a dark suit, a tiny smile often curling at the corner of his mouth. His public profile was about to explode. A publisher was finalizing a book about the
Nothing really prepares one for the experience of entering the
Last August, the author
For the last 60 years or so, science has been running an experiment on itself. The experimental design wasn’t great; there was no randomization and no control group. Nobody was in charge, exactly, and nobody was really taking consistent measurements. And yet it was the most massive experiment ever run, and it included every scientist on Earth.
Many opponents of Netanyahu’s judicial overhaul have called for Israel to finally draft a constitution, but any serious attempt will mean choosing between a democratic state and one that privileges Jewish citizens above all others.
“She had no sympathy,” Spiegelman tells us, “for people who paraded their inner misfortunes.” Clampitt’s dismissive attitude toward the self-indulgences of confessional verse, which commanded so much attention in the 1960s and 1970s, was a product, he writes, of “her stern midwestern upbringing.” And her models: Hopkins,
One morning in Maine, soon after dawn, I stood by the ocean just as a light fog began moving in. The rising sun became a gauzy fire. Suddenly, the air started to glow. Fog scattered the sunlight, bounced it around and back and forth until each cupful of air shone with its own source of light. In all directions, the air beamed and shimmered and glowed, and the gulls stopped their squawking and the ospreys became quiet. For some time, I stood there spellbound by the silence and the glowing air. I felt as if inside a cathedral of sunlight and air. Then the fog burned away and the glow disappeared.