How a Guy From a Montana Trailer Park Overturned 150 Years of Biology

Ed Yong in The Atlantic:

In 1995, if you had told Toby Spribille that he’d eventually overthrow a scientific idea that’s been the stuff of textbooks for 150 years, he would have laughed at you. Back then, his life seemed constrained to a very different path. He was raised in a Montana trailer park, and home-schooled by what he now describes as a “fundamentalist cult.” At a young age, he fell in love with science, but had no way of feeding that love. He longed to break away from his roots and get a proper education.

At 19, he got a job at a local forestry service. Within a few years, he had earned enough to leave home. His meager savings and non-existent grades meant that no American university would take him, so Spribille looked to Europe.

Thanks to his family background, he could speak German, and he had heard that many universities there charged no tuition fees. His missing qualifications were still a problem, but one that the University of Gottingen decided to overlook. “They said that under exceptional circumstances, they could enroll a few people every year without transcripts,” says Spribille. “That was the bottleneck of my life.”

Throughout his undergraduate and postgraduate work, Spribille became an expert on the organisms that had grabbed his attention during his time in the Montana forests—lichens.

More here.

The history and politics of white identity

Kenan Malik in Pandaemonium:

Identity politics is one of the defining – and one of the most divisive – issues of our age. And no identity is more contested or fought over than white identity. For some it is a means of giving voice to a group whose identity has previously been denied. For others it is simply as an expression of racism.

The political context of the emergence of white identity is that of the rise of populism, of politicians such as Donald Trump in America and of Victor Orban and Matteo Salvini in Europe, of growing hostility to immigration and of the rise of nativism.

In much of the debate around these changes, the politics of identity is seen primarily a politics of the left, the politics of minority and oppressed groups. White identity is viewed as a latecomer on the scene, an attempt by whites to replicate the success of minority groups.

I want to turn this perception on its head. The origins of the politics of identity lie not on the left but on the reactionary right. Radical forms of identity politics were the ones late on the scene. Now, contemporary white identity is reclaiming its original reactionary heritage.

To understand all this, I want to retrace the history of identity politics, to tell the story of identity politics before it was called identity politics.

More here.

Greek to a Greek

Wolfgang Streeck in Inference Review:

WHAT A STRANGE book—strange but indispensable nevertheless. From January to July 2015, Yanis Varoufakis served as the Greek government’s finance minister. Adults in the Room is an account of his battle with what he calls Europe’s deep establishment. It is often self-indulgent, sometimes sentimental. He also takes pains to show he is human. He describes his happy marriage. He takes dinner with friends. He remembers his student days, and argues with his daughters. He encounters German secret service agents who unaccountably urge him to continue fighting the good fight. His mistakes he assigns to a nature that is too trusting given the intrigues both abroad and at the court of Alexis Tsipras, his prime minister and the leader of Syriza.

And yet, the book is indispensable. For whom? For the journalists who helped the masters of Europe get rid of Varoufakis; for the armies of European functionaries, les ronds-de-cuir; and, one might hope, for teachers and students of the policy sciences. Varoufakis’s book provides an honest account of how our world is governed. It will be plausible to anyone who has tried to make sense of political life without falling victim to the charm of political power.

More here.

Death of the calorie

Peter Wilson in  MIL:

As a general rule it is true that if you eat vastly fewer calories than you burn, you’ll get slimmer (and if you consume far more, you’ll get fatter). But the myriad faddy diets flogged to us each year belie the simplicity of the formula that Camacho was given. The calorie as a scientific measurement is not in dispute. But calculating the exact calorific content of food is far harder than the confidently precise numbers displayed on food packets suggest. Two items of food with identical calorific values may be digested in very different ways. Each body processes calories differently. Even for a single individual, the time of day that you eat matters. The more we probe, the more we realise that tallying calories will do little to help us control our weight or even maintain a healthy diet: the beguiling simplicity of counting calories in and calories out is dangerously flawed. The calorie is ubiquitous in daily life. It takes top billing on the information label of most packaged food and drinks. Ever more restaurants list the number of calories in each dish on their menus. Counting the calories we expend has become just as standard. Gym equipment, fitness devices around our wrists, even our phones tell us how many calories we have supposedly burned in a single exercise session or over the course of a day.

It wasn’t always thus. For centuries, scientists assumed that it was the mass of food consumed that was significant. In the late 16th century an Italian physician named Santorio Sanctorius invented a “weighing chair”, dangling from a giant scale, in which he sat at regular intervals to weigh himself, everything he ate and drank, and all the faeces and urine he produced. Despite 30 years of compulsive chair dangling, Sanctorius answered few of his own questions about the impact that his consumption had on his body.

Only later did the focus shift to the energy different foodstuffs contained. In the 18th century Antoine Lavoisier, a French aristocrat, worked out that burning a candle required a gas from the air – which he named oxygen – to fuel the flame and release heat and other gases. He applied the same principle to food, concluding that it fuels the body like a slow-burning fire. He built a calorimeter, a device big enough to hold a guinea pig, and measured the heat the creature generated to estimate how much energy it was producing. Unfortunately the French revolution – specifically the guillotine – cut short his thinking on the subject. But he had started something. Other scientists later constructed “bomb calori­meters” in which they burned food to measure the heat – and thus the potential energy – released from it.

More here.

Forget Everything You Think You Know About Time

Brian Gallagher in Nautilus:

Last April, in the famous Faraday Theatre at the Royal Institution in London, Carlo Rovelli gave an hour-long lecture on the nature of time. A red thread spanned the stage, a metaphor for the Italian theoretical physicist’s subject. “Time is a long line,” he said. To the left lies the past—the dinosaurs, the big bang—and to the right, the future—the unknown. “We’re sort of here,” he said, hanging a carabiner on it, as a marker for the present. Then he flipped the script. “I’m going to tell you that time is not like that,” he explained.

Rovelli went on to challenge our common-sense notion of time, starting with the idea that it ticks everywhere at a uniform rate. In fact, clocks tick slower when they are in a stronger gravitational field. When you move nearby clocks showing the same time into different fields—one in space, the other on Earth, say—and then bring them back together again, they will show different times. “It’s a fact,” Rovelli said, and it means “your head is older than your feet.” Also a non-starter is any shared sense of “now.” We don’t really share the present moment with anyone. “If I look at you, I see you now—well, but not really, because light takes time to come from you to me,” he said. “So I see you sort of a little bit in the past.” As a result, “now” means nothing beyond the temporal bubble “in which we can disregard the time it takes light to go back and forth.”

Rovelli turned next to the idea that time flows in only one direction, from past to future. Unlike general relativity, quantum mechanics, and particle physics, thermodynamics embeds a direction of time. Its second law states that the total entropy, or disorder, in an isolated system never decreases over time. Yet this doesn’t mean that our conventional notion of time is on any firmer grounding, Rovelli said. Entropy, or disorder, is subjective: “Order is in the eye of the person who looks.” In other words the distinction between past and future, the growth of entropy over time, depends on a macroscopic effect—“the way we have described the system, which in turn depends on how we interact with the system,” he said.

More here.

Sunday Poem

A Refugee in Paris

What do I know of this city
A migrant, a refugee
Carrying a storehouse of fears

Its splendor faded
In the falling light
Its step sprouting
Tense, sinister shadows
Shrouded in suspicions

What do I know of this city
A stranger skirting light and shadows
Seeking a place to bury
Restless thoughts

by Anjum Altaf
from Transgressions— Poems inspired by Faiz Ahmed Faiz
LG Publishers, 2019

James Joyce’s Dublin, A Microcosm Of The World

Sarah Baxter in Literary Hub:

The pub is warm and beery. Grog glasses—drained, foam stained—scatter sticky veneer. Red-wine lips, hoppy breath, a slurry of slurring; laughter like gunfire, craic-ing off the wood panels, mirror walls and ranks of whiskey bottles. Bar talk is of theology and adultery, literature and death, soap and sausages. Everything and nothing, discussed or daydreamed over a quick cheese sandwich. A nothing old day. But the stuff of life—infinitesimal yet essential—all the same . . .

James Joyce’s Ulysses—variously considered the most momentous, accomplished, infuriating and unreadable book in the English language—is the ordinary made extraordinary. It’s a modernist reworking of Homer’s Odyssey, but while the Ancient Greek poem tells of Odysseus’ incident-packed return from the Trojan War, Joyce makes an epic out of a single, unremarkable day.

Ulysses follows Leopold Bloom, a Jewish ad canvasser for The Freeman’s Journal, as he wanders around Dublin on June 16, 1904. He attends a funeral, goes to the pub, ducks into a museum (to avoid the man sleeping with his wife), pleasures himself by Sandymount Strand, enters the red-light district. The novel is a chaotic stream of consciousness, performing stylistic acrobatics to try to render the human experience. But it is grounded in the streets of Dublin. Joyce, writing from self-exile in Paris, slavishly researched the physicality of the city. Though he seldom returned, he remained tethered: “When I die,” he once said, “Dublin will be written in my heart.”

More here.

Finding the right “dose” for solar geoengineering

Leah Burrows at the website of the Harvard School of Engineering:

One of the key misconceptions about solar geoengineering — putting aerosols into the atmosphere to reflect sunlight and reduce global warming — is that it could be used as a fix-all to reverse global warming trends and bring temperature back to pre-industrial levels.

It can’t. Applying huge doses of solar geoengineering to offset all warming from rising atmospheric C02 levels could worsen the climate problem — particularly rainfall patterns — in certain regions. But could smaller doses work in tandem with emission cuts to lower the risks of a changing climate?

New research from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS), in collaboration with MIT and Princeton University, finds that if solar geoengineering is used to cut global temperature increases in half, there could be worldwide benefits without exacerbating change in any large geographic area.

More here.  [Thanks to Steven Pinker.]

A constitution should help a country govern, not hobble it

Samir Chopra in Aeon:

The United States and India, two of the world’s largest and oldest democracies, are both governed on the basis of written constitutions. One of the inspirations for the Constitution of India, drafted between 1947 and 1950, was the US Constitution. Both Indians and Americans revere their ‘constitutional rights’ – especially the ‘fundamental right’ of free speech, and the separation of state and religion. Both countries support critical traditions that focus on particular clauses of the constitution. In India, Article 356, which allows for the suspension of state legislative assemblies to permit ‘direct rule by the centre’, has provoked considerable critique, while in the US, the Second Amendment is a source of perpetual political and legal discord. The Indian and US supreme courts both enjoy the power of judicial review, to declare acts of other branches of government illegitimate, and so a measure of ‘supremacy’ over their respective legislative branches. For this reason, both constitutions are ‘undemocratic’ in their arrogation of too much political power to the judicial bench – a group of unelected public servants.

The US and Indian constitutions diverge in their ‘stability’ or ‘flexibility’. The US Constitution is very difficult to change and, thanks to a religious American sensibility that treats it as a sacral document, it has simply not evolved, impervious to the changing needs of a growing and progressing nation and world. The Constitution of India suffers from the converse flaw; in less than 75 years, it has been amended, at last count, 103 times.

More here.

‘I Will Never See the World Again’ by Ahmet Altan

Simon Callow at The Guardian:

To review certain books seems like an impertinence. This is one of them. It speaks for itself with such clarity, certainty and wisdom that only one thing needs to be said: read it. And then read it again. It is a short book, divided into brief chapters, some no longer than two pages, each recounting some incident from the author’s prison experience. It is wonderfully distilled, but not sententious; even in extremis, Altan never loses the limpidity and translucence, vivid with the vividness of dreams, which is characteristic of his other writing – as far as one can judge from the only other books of his available in English translation, Like a Sword Wound, the superb first volume of his Ottoman Quartet; and Endgame, a phantasmagorical crime story. Even the latter has, at the heart of all the violence, a dreamy, wide-eyed quality that seems to be quintessential Altan. To judge by I Will Never See the World Again, it has been and will be his salvation.

more here.

On Walter Kempowski’s “Homeland”

Stephanie Sy-Quia at the LARB:

Homeland is essentially a road trip novel, but its road trip doesn’t work. Contra to the willful American model of making off into the great vistas of the West, Jonathan and his feckless companions (a racing driver and a sexist caricature of a press officer, Frau Winkelvoss) can’t escape the traumas of East Prussia’s landscape. To paraphrase Joan Didion, history has very much bloodied the land here, leaving it irrevocably besmirched and hard to navigate (as the aptly titled Bloodlands: Europe Between Hitler and Stalin by Timothy Snyder can attest). Instead of experiencing the desired transcendental realization while standing on the Vistula Spit, Jonathan thinks about the “chests of drawers and grandfather clocks” on wagons making their way across the Wisła while under fire from British bombers and Red Army tanks, and that when the ferries crammed with refugees sank, and the dishes in their mahogany dining rooms slid to the floor, “no-one sang hymns.” The final pages of the novel see him scooping some sand from the presumed spot of his father’s death into a medicine bottle, with the vague hope that a forensic lab will be able to analyze it for DNA — a final bathetic pun on the notion of the German fatherland.

more here.

‘Omer Pasha Latas’ by Ivo Andric

Natalia Holtzman at The Quarterly Conversation:

Andrić is particularly remarkable for his psychological acuity. Consider the knot of complexity that is Omer Pasha: born Mićo Latas, he’d been a brilliant boy in a village too small to contain his ambitions. He was bored by his parents and the provincial people around him. He managed to acquire a scholarship to military school—Austrian, not Turkish—but, just as he is ready to graduate, he receives word that his father, a minor officer, “a weak man…a small, overlooked man,” has been indicted for misuse of state funds. The stigma will prevent Mićo from achieving any career at all. This is when he takes off for Istanbul to scrape together an entirely new life.

When he returns, he has a new name, a new religion, and an army trailing in his wake. But there isn’t a soul in Sarajevo who doesn’t know of the pasha’s conversion.

more here.

How to Talk About the New Zealand Massacre: More Sunlight, Less Oxygen

Evan Osnos in The New Yorker:

The New Zealand killer takes his place in the cracked pantheon of violent, Trump-admiring extremists: beside the gunman at the Tree of Life synagogue, in Pittsburgh, who blamed Jews for resettling refugees and immigrants, whom Trump vilifies as the center of his politics; beside the van-dweller in Miami who found purpose amid the throngs of Trump rallies and set about sending pipe bombs to George Soros, journalists, and Democrats. The New Zealand killer did not exact his violence in America, but he would be at home in our statistics: in the past decade, seventy-three per cent of all American extremist-related killings have come from the right wing, compared to twenty-three per cent from Salafi jihadism and three per cent from the left wing, according to the Soufan Center, which studies global security.

Pointing out those patterns does not feed oxygen to the sources; it subjects them to the disinfecting power of sunlight. We can only have an honest analysis of the sources of this violence if we understand how it grows and spreads. That applies not only to the role of journalism but also to the role of technology. Whenever a killer relies, as he did in this case, on the Internet to amplify the effects of his terror, some inevitably defend social media as no better and no worse than the humanity that uses it. Don’t blame the hammer, we are told; blame the hand. At best, that is a deflection. One does not have to be a Luddite to believe that the worst of social media is not a mirror image of us; it is a grotesque distortion, a funhouse mirror that bulges and squeezes and disfigures us in ways that mock our humanity instead of reinforcing it.

Once again, Facebook finds itself scrambling to explain how it will prevent its creations from being used for harm.

More here.

When Science Fiction Comes True

Namwali Serpell in The New York Times:

Maybe because we’re living in a dystopia, it feels as if we’ve become obsessed with prophecy of late. Protest signs at the 2017 Women’s March read “Make Margaret Atwood Fiction Again!” and “Octavia Warned Us.” News headlines about abortion bans and the defunding of Planned Parenthood do seem ripped from the pages of Atwood’s novel “The Handmaid’s Tale” (1985). And Octavia Butler’s “Parable” series, published in the 1990s, did eerily feature a presidential candidate who vows to “make America great again.”

…I write science fiction set in the near future, so I’m constantly testing my own powers of prophecy. I once wrote a story about a germaphobic couple who want to have sex without touching. They purchase the “TouchFeely” — my nod to the “Feelies” in Aldous Huxley’s “Brave New World” (1932) — an apparatus that includes an electrified dildo and a sheath that respond remotely to each other. The year after the story came out, I learned about Hera and Zeus, “the world’s first internet-enabled” sex toys. These “teledildonic” devices uncannily resemble my fictional invention. I was a little disconcerted. My story is a satire about bourgeois disconnection. My characters each start affairs with the bot. One ends up choking on the dildo. But I’ll confess: I felt a perverse pleasure, too. It was as if I had conjured something into existence — the dream of every artist.

More recently, I did some research on H.I.V. vaccines for my novel, “The Old Drift.” With some help from a biologist at New York University, I came up with one that uses a particular technique to target a specific gene sequence. I felt a strange, and, again, perverse, mix of horror and wonder when I read a couple months ago that Chinese scientists had used the exact same mechanism for their “AIDS vaccine development project,” also known as the CRISPR babies, the first genetically modified humans.

More here.

Against Bipartisanship

Robert B. Talisse in 3:AM Magazine:

To be sure, the bipartisan civic ethos is an indispensable ingredient of a flourishing democracy.  But it cannot be cultivated under conditions where everything we do is plausibly regarded an expression of our political loyalties.  When politics is all we ever do together, our efforts to repair democracy by means of strategies for enacting better politics are doomed simply to backfire.  What is required instead is the reclaiming of regions of social space for shared activities that are in no way political, occasions for cooperative endeavors in which the participants’ political affiliations are not merely suppressed or bracketed, but irrelevant and out of place.  If you now find yourself wondering whether such collaborations could possibly exist, you have placed your finger firmly on the problem of polarization.  For polarization has led not only to the colonization of our social environments by politics, it also has enabled politics to seize and confine our social imagination.  That we must struggle to conceptualize avenues of social collaboration that are not structured around our political identities is the fullest manifestation of the problem of polarization.  To frame the upshot somewhat paradoxically, if we want to repair our democracy, we need to focus our collective attention elsewhere.

More here.

Ketamine: Now By Prescription

Scott Alexander in Slate Star Codex:

Let’s review how the pharmaceutical industry works: a company discovers and patents a potentially exciting new drug. They spend tens of millions of dollars proving safety and efficacy to the FDA. The FDA rewards them with a 10ish year monopoly on the drug, during which they can charge whatever ridiculous price they want. This isn’t a great system, but at least we get new medicines sometimes.

Occasionally people discover that an existing chemical treats an illness, without the chemical having been discovered and patented by a pharmaceutical company. In this case, whoever spends tens of millions of dollars proving it works to the FDA may not get a monopoly on the drug and the right to sell it for ridiculous prices. So nobody spends tens of millions of dollars proving it works to the FDA, and so it risks never getting approved.

The usual solution is for some pharma company to make some tiny irrelevant change to the existing chemical, and patent this new chemical as an “exciting discovery” they just made. Everyone goes along with the ruse, the company spends tens of millions of dollars pushing it through FDA trials, it gets approved, and they charge ridiculous prices for ten years. I wouldn’t quite call this “the system works”, but again, at least we get new medicines.

Twenty years ago, people noticed that ketamine treated depression. Alas, ketamine already existed – it’s an anaesthetic and a popular recreational drug – so pharma companies couldn’t patent it and fund FDA trials, so it couldn’t get approved by the FDA for depression.

More here.