Rashid Arshed. ID-eighty-five.

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Sarah Sweeney in the Harvard Gazette:

Per-Olof Hasselgren already knew English when he arrived to the United States from Sweden 31 years ago, but in his stateside conversations, he couldn’t help but sense an owl in the moss.

Befuddled when someone remarked that something was “fishy,” Hasselgren didn’t yet grasp American slang and idiomatic expressions. “Something’s fishy” wouldn’t make much sense directly translated into Swedish, but Hasselgren eventually located its Swedish counterpart, that aforementioned head-scratching phrase involving feathered critters in a bog. (Another American expression, “to beat around the bush,” would mean to “walk like a cat around hot porridge” in Sweden.)

The George H. A. Clowes, Jr. Professor of Surgery at Harvard Medical School and surgeon at Beth Israel Deaconess Medical Center began keeping a log of these newfound turns of language as he discovered them, learning that quite a bit of American slang was based on anatomy and body parts, his specialty.

Though the surgeon spends most of his days focusing on endocrine organs, phrases like “foot in one’s mouth” and “tongue-tied” truly piqued his interest, along with the idea that expressions can be both funny and educational.

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Liam Heneghan in the Los Angeles Review of Books:

I am writing in a coffee shop. Ostensibly, there is only one species in this crowded room, a medium-sized primate with a penchant for disruption. But knowing a thing or two about species diversity — I am a zoologist by training — I realize there are more species in the room than meet the eye. For now, though, think of each human as an ecosystem of sorts, complete with its native cells, tissues, and organs, and think of the non-human organisms as non-native invasive species.

Put to the back of your mind images of those pestiferous insects and microbes that inhabit the pantries of every coffee shop on Earth. Also ignore thoughts of the family of mice scrambling for crumbs under the counter. After all, the bewildering diversity of organisms invading the primate body is unsettling enough, so let’s stick to these “invasives.” Amoebae glide over cankerous gums, armies of micro-invertebrates storm the hairier and damper alcoves of the body, and the skin itself is as coated with bacteria as a commode in a gas station. Inside the body, the species count is impressively high. Up to 1000 bacterial species inhabit the gut. Many are not casual hitch-hikers but essential to health, metabolizing nutrients and synthesizing key vitamins. To be sure, among the invading hordes are a few bad eggs. Plague, for example, is ghastly. And smallpox is to be avoided. But most cause nothing more than the sniffles, a mild rash, or a headache. Nothing to be too alarmed about — and, after all, you deserve that day off work.

Despite the outright helpfulness of some members of our bodily menagerie, and the fact that many of the others felicitously augment diversity, we have declared an all-out war against microbes. All because of a few bad eggs! Rather than vilifying these aliens as intruders, I argue that it is now time to embrace them as the key to our salvation.

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The world’s most dangerous malaria parasite shuffles its genes in a clever attempt to avoid the immune system. A new approach has begun to reveal how the process works.

Veronique Greenwood in Quanta:

Think of a deck of cards,” said Dan Larremore. Now, take a pair of scissors and chop the 52 cards into chunks. Throw them in the air. Card confetti rains down, so the pieces are nowhere near where they started. Now tape them into 52 new cards, each one a mosaic of the original cards. After 48 hours, repeat.

You have just reenacted the process that Plasmodium falciparum uses to avoid the immune system. P. falciparum is the world’s most dangerous malaria parasite, causing 600,000 deaths every year and killing more children under the age of 5 than any other infectious disease on the planet. Larremore, an applied mathematician, was introduced to its promiscuous habits while doing postdoctoral research at what is now the Harvard T.H. Chan School of Public Health.

Each card represents a gene for a protein that attaches to the walls of the host’s blood vessels, anchoring the parasite so that it cannot be dragged into the spleen, where it would be detected and destroyed. Each falciparum parasite has 50 to 60 of these vargenes, as they are called, and as time passes the parasite uses first one, then another, presenting a constantly morphing face to immune cells that might spot it clinging to the blood vessel. The crowning glory of this tactic, though, is that when the parasite divides, which it does every couple of days, chunks and snippets of the genes swap places up and down the chromosomes. In one out of every 500 parasites, this process will generate an entirely new gene. With the number of parasites out there, that adds up quickly. “It’s crazy. It means the total number of var gene sequences in the world is millions and millions — virtually infinite,” said Antoine Claessens, a malaria researcher with the Medical Research Council, The Gambia Unit, in Fajara.

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Craig Mod in Aeon:

From 2009 to 2013, every book I read, I read on a screen. And then I stopped. You could call my four years of devout screen‑reading an experiment. I felt a duty – not to anyone or anything specifically, but more vaguely to the idea of ‘books’. I wanted to understand how their boundaries were changing and being affected by technology. Committing myself to the screen felt like the best way to do it.

By 2009, it was impossible to ignore the Kindle. Released in 2007, its first version was a curiosity. It was unwieldy, with a split keyboard and an asymmetrical layout that favoured only the right hand. It was a strange and strangely compelling object. Its ad-hoc angles and bland beige colour conjured a 1960s sci-fi futurism. It looked exactly like its patent drawing. (Patent drawings are often abstractions of the final product.) It felt like it had arrived both by time machine and worm hole; not of our era but composed of our technology.

And it felt that way for good reason: you could trace elements of that first Kindle – its shape, design, philosophy – back 70 years. It evoked the Memex machine that the American inventor Vannevar Bush wrote about in ‘As We May Think’ (1945), a path-breaking essay for The Atlantic. It went some way toward vindicating Marshall McLuhan’s prediction that ‘all the books in the world can be put on a single desktop.’ It was a near‑direct copy of a device called the Dynabook that the early computer pioneer Alan Kay sketched and cardboard‑prototyped in 1968. It was a cultural descendant of the infinitely paged Book of Sand from a short story of the same name by Jorge Luis Borges published in 1975. And it was something of a free-standing version of the ideas of intertwingularity and hypertext that Ted Nelson first posited in 1974 and Tim Berners-Lee championed in the 1990s.

The Kindle was all of that and more. Neatly bundled up. I was in love.

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Oliver Morton in More Intelligent Life:

As a gadget to plug into a USB port, the “MinION” recently unveiled by Oxford Nanopore lacks the touch-me buy-me pizazz of Jonathan Ive’s designs. And since it’s a prototype that no one outside the company and a few partner organisations has yet been able to see in action, it is hard to say how well it actually works. But as an embodiment of technological cool it strikes me as pretty much beyond compare. Inside the MinION is a little chip with 512 holes in it. Put some DNA into the MinION, and it will pull individual DNA molecules through those pores. DNA molecules carry genetic information in the form of four different chemical bases, like slightly different knots on a piece of string. As a DNA molecule goes through one of the MinION’s pores, the different knots on it are sensed electronically; the signals produced this way are processed inside the MinION and sent through the USB port to your computer, where the string of bases is reassembled as a genome sequence. How long are the pieces of string? The system can read individual strings tens of thousands of bases long—far longer than most sequencing technologies. A MinION should be able to read about a billion bases before its pores run out. That’s a third the length of a human genome. All in a device the size of a matchbox.

There’s no good way of putting a cost on the production of the first human genome sequence in the early 2000s, but the number people tend to quote is $3 billion. The technology in the MinION will apparently do it for well under $3,000. Getting a million times cheaper in ten years is quite a feat even by the standards of…well, by any standards at all. As a byword for head-spinning progress, we’re accustomed to thinking of Moore’s Law, which says (more or less) that the computing power available for a given price doubles every two years. But that gives you only a thousandfold improvement every 20 years. A millionfold in just ten really is something else.

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Freddie deBoer in Full Stop:

Did you hear? Google has dreams! And they’re really trippy. You’ve got to check it out.

Since Google’s “Deep Dream” project landed with great fanfare onto our collective Twitter feeds, it’s prompted a mountain of online aggregation, analysis, and sharing. And there’s little wonder why. With beautiful/disturbing/uncanny visuals, references to the impressive-sounding “artificial neural networks,” and origins in one of the most fascinating companies in the world, the story is a click farmer’s dream. It’s no surprise that so many publishers rushed to fill the stream with takes on the technology.

Unfortunately, much of the actual information sharing of these pieces – you know, thejournalism – has been counterproductive. With click-begging headlines, useless metaphors, vague discussion of essential information, and the general ambient woowoo that chokes our tech media, stories about Deep Dream have demonstrated the capacity for aggregation-style internet journalism to mislead. Faced with an interesting but limited project, one which utilizes complex technologies that require nuance and care to talk about meaningfully, our professional technology writers have fallen down, hard, on the job.

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Spencer Jordan in The Wire:

In Middle Passage (1962), V S Naipaul’s account of revisiting the Caribbean, the author is swept up by the voices of its inhabitants. As one taxi driver tells him: “Is only when you live here as long as me that you know the sort of animal it is.” Understanding exactly what sort of “animal” Jamaica is also lies at the heart of Marlon James’s Booker-winning novel A Brief History of Seven Killings.

Like Middle Passage, James’s book is a whirlwind of different voices, intertwining and separating as the novel proceeds. Yet unlike Middle Passage there is no artful attempt to spare the darkness of what was once the heart of the slave trade. As one of James’s characters says when talking about Naipaul’s travelogue, “the beauty of how him write that sentence still lie to you as to how ugly [West Kingston] is”.

Ostensibly A Brief History of Seven Killings is about the failed assassination of Bob Marley, immediately before a peace concert organised by the socialist People’s National Party (PNP) in 1976. Marley was wounded but went on to play the concert. He left straight afterwards and did not return to Jamaica for two years. The gunmen were never brought to justice and their identities remain a mystery.

The fog of uncertainty surrounding these events has elevated them to mythical status. James takes the few facts that are known and runs with them…

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Michael M. Phillips in the Wall Street Journal:

There was nobody in Jimmy Lee Dykes’s life to take the edge off his anger.

He had long ago lost touch with an ex-wife and two daughters. His older girl recalled his fondness of firearms and a hatred of authorities; how he smelled of spearmint, coffee and cigarettes; how he beat her mother.

Mr. Dykes, a Vietnam veteran, worked as a land surveyor and a truck driver. He was fired from his last hauling job after a dispute with his boss and at age 65 ended up living on the edge of a peanut field in a town of 2,400 in southeastern Alabama, growing vegetables and collecting grievances.

Metal cattle gates opened to his acre-and-a-half property, located at the crest of a rutted, red-dirt road. He landscaped with cinder block and laid out a pond and garden. Mostly, though, his land resembled a scrub-covered parking lot for his maroon-and-silver Econoline van, a 40-foot shipping container and, up on blocks, his home, a scruffy trailer left over from a federal disaster-relief program.

In jeans and a T-shirt, with lightning-strike white hair, Mr. Dykes roamed his property shooting grasshoppers with a pellet gun. He talked about putting out bowls of antifreeze to poison neighborhood dogs that soiled his property.

In early 2012, Mr. Dykes drove his next-door neighbor, Michael Creel, to the Wal-Mart and spent the ride fuming over a new gun law. On the return trip, Mr. Dykes mused about taking people hostage in a church some Sunday until a reporter broadcast his views against the law.

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