Inspiring Evolutionary Thought, and a New Title, by Turning Genetics Into Prose

From The New York Times:Dawkins_9

Thirty years ago, a young biologist set out to explain some new ideas in evolutionary biology to a wider audience. But he ended up restating Darwinian theory in such a broad and forceful way that his book has influenced specialists as well. “Richard Dawkins: How a Scientist Changed the Way We Think” is a collection of essays about Dr. Dawkins’s book “The Selfish Gene” and its impact. Contributors to the book, edited by Alan Grafen and Matt Ridley, are mostly biologists but include the novelist Philip Pullman, author of “His Dark Materials,” and the bishop of Oxford, Richard Harries.

The biologists have copious praise for Dr. Dawkins’s work of synthesis, while the writers remark on his graceful and vivid style. It is quite surprising for anyone to be commended from such opposite quarters, but “The Selfish Gene,” published in 1976, was unusual. Written in clear and approachable language, it worked its way so logically into the core of Darwinian theory that even evolutionary biologists were seduced into embracing Dr. Dawkins’s view of their world.

Dr. Dawkins’s starting point was the idea that the gene, not the individual, is the basic unit on which natural selection acts. The gene’s behavior is most easily understood by assuming its interest is to get itself replicated as much as possible — hence the “selfish” gene of the title.

More here.

Scientists get inside look at viruses

From MSNBC:Virus_1

Exactly 25 years ago, in the body of the world’s first diagnosed AIDS case, the full capabilities and mysterious workings of a virus unfolded. Three years later, in 1984, Luc Montagnier of the Pasteur Institute of Paris and Robert Gallo, then of the National Cancer Institute, announced their discovery of HIV, the virus that infects the human immune system and causes AIDS.

Even though the smallest viruses are only about one-millionth of an inch long, they live up to their Latin namesake — poison. They are capable of infecting and hijacking a human body, creating health hazards as minor as the common flu and as disastrous as the AIDS epidemic.Viruses are neatly organized, petite packages of genetic material, shaped like rods, filaments, harpoons, or spheres. Proteins surround the package, which is called a capsid. Some viruses have an added layer of lipids that coat the capsid. Little extensions on the virus are called antigens, which help the virus hunt down the target host cell.

More here.

THE HORNINESS GENE

Maggie Wittlin in Seed Magazine:

SexgeneAre you unhappy with your ability to function sexually? Do you lack interest in sex or find it difficult to become aroused? Are you unsatisfied with your orgasms? If so, you may be genetically predisposed to have a moderate to low sex drive.

Israeli researchers published a study online in the April 18th issue of Molecular Psychiatry suggesting a link between a dopamine receptor gene and human sexual desire, arousal and function. They conclude that one gene variant found in about 60% of the population may lead to a more subdued sex drive while another, found in about 30% of the population, contributes to higher sexual desire, arousal and function.

More here.

SEPTUAGENARIAN SEX

Virginia Ironside reviews Unaccompanied Women by Jane Juska, in the Literary Review:

As this is a book about a book, in order to get through this one, you need to have waded through the first one: Jane Juska’s A Round-Heeled Woman: My Late-Life Adventures in Sex and Romance. In this, the author recounted what happened after she’d placed an advertisement in the New York Review of Books which read: ‘Before I turn 67 – next March – I would like to have a lot of sex with a man I like. If you want to talk first, Trollope works for me.’ Billed as a strike for sexual freedom for the mature (actually very mature) woman, it came across as a tragic wail from someone who was young in the Fifties but who clearly wished she’d been young in the Sixties.

As a result of the ad, Jane managed to get quite a few orgasms under her belt but oh, what a price she had to pay! Eighty-two-year-old Jonah, for example, insisted she talked dirty the first night and, on the second, announced that he didn’t desire her – ‘Get yourself some KY jelly. You get dry before I can get in, and I can’t keep it up long enough for you to get wet,’ he said, brutally, before fleeing with the two champagne flutes that she’d brought to drink from, not to mention the trousers of her red silk jim-jams. Then she met Robert. He was a member of AA and already had a girlfriend, whom he rang repeatedly, in order to tell her he loved her. He had also started drinking again. The following lovers were equally, if not more, unappetising (one of them sucked boiled sweets when they had sex) and finally she bumped into the much younger Graham, whom she adored because he pompously uttered this smug and well-worn cliché, which it appears she had never heard before in her life: ‘The greatest pleasure for me in making love is giving the other person pleasure.’

In her latest book, Juska tells us what happened next.

More here.

In West Bank, a First Hint of Agriculture: Figs

John Noble Wilford in the New York Times:

Figs_650_1In the ruins of a prehistoric village near Jericho, in the West Bank, scientists have found remains of figs that they say appear to be the earliest known cultivated fruit crop, perhaps the first evidence anywhere of domesticated food production at the dawn of agriculture. The figs were grown some 11,400 years ago.

Presumably that was well after Adam and Eve tried on the new look in fig leaves, in which case the fig must have grown wild in Eden.

Two botanists and an archaeologist, who describe the discovery in today’s issue of the journal Science, said the figs came from cultivated trees that grew about 1,000 years before such staples as wheat, barley and chickpeas were widely domesticated in the Middle East. These grain and legume crops had been considered the first steps in agriculture.

More here.

Monday, June 5, 2006

Sunday, June 4, 2006

The Long Interrogation

“When Edgegayehu Taye took a job in an Atlanta hotel, she never expected the service elevator doors to open one day and reveal the man who tortured her years before in Ethiopia. Nor could she have predicted what it would take to see justice done.”

Andrew Rice in the New York Times Magazine:

04torture1

Six months after he arrived in America, Kelbessa applied for political asylum, saying he had been persecuted and imprisoned by Ethiopia’s military dictatorship. It was the Reagan era, and Ethiopia was Communist; the application was quickly approved. Kelbessa then set about achieving his next goal: saving enough money to send for his three children, who were still stuck in Ethiopia. (He and his wife were divorced.) He worked the graveyard shift at a convenience store and took a second job, washing dishes at the Colony Square Hotel. Later, he was promoted to bellhop.

One afternoon, Kelbessa was outside the employee locker room, waiting for the service elevator. The elevator doors opened, and another Ethiopian walked out, a young woman in a waitress’s uniform.

More here.

The rebirth of electric-shock treatment

From The Economist:

Electricity has long been used to treat medical disorders. As early as the second century AD, Galen, a Greek physician, recommended the use of electric eels for treating headaches and facial pain. In the 1930s Ugo Cerletti and Lucio Bini, two Italian psychiatrists, used electroconvulsive therapy to treat schizophrenia. These days, such rigorous techniques are practised less widely. But researchers are still investigating how a gentler electric therapy appears to treat depression.

Vagus-nerve stimulation, to give it its proper name, was originally developed to treat severe epilepsy. It requires a pacemaker-like device to be implanted in a patient’s chest and wires from it threaded up to the vagus nerve on the left side of his neck. In the normal course of events, this provides an electrical pulse to the vagus nerve for 30 seconds every five minutes.

This treatment does not always work, but in some cases where it failed (the number of epileptic seizures experienced by a patient remaining the same), that patient nevertheless reported feeling much better after receiving the implant. This secondary effect led to trials for treating depression and, in 2005, America’s Food and Drug Administration approved the therapy for depression that fails to respond to all conventional treatments, including drugs and psychotherapy.

More here.

Reaching Out to Iran

David Ignatius in the Washington Post:

America’s opening to China had its ping-pong diplomacy. Detente with the Soviet Union featured the Bolshoi Ballet. Perhaps in the new diplomatic dance between the United States and Iran, a similar people-to-people role will be played by an immunologist named David Haines and his project to study Iranian victims of Iraqi chemical weapons.

Haines first told me his unlikely story several months ago, as he was seeking U.S. government approval for his effort to bring an Iranian scientist to join him in his work at the University of Connecticut. The urgency of his project became obvious after Secretary of State Condoleezza Rice announced Wednesday that the United States is willing to join direct talks with Iran for the first time in nearly three decades. Perhaps Haines’s project can be a model for broader educational and scientific contacts if a U.S.-Iran dialogue can begin.

Haines’s tale features many of the strands that are knotted together in the current Middle East crisis: weapons of mass destruction; the aftershocks of Saddam Hussein’s brutal regime; the legacy of the Sept. 11, 2001, attacks; the need to prepare for future WMD attacks by terrorist groups. You may doubt that all those themes could converge in the work of one scientist, but read on.

More here.  [Thanks to Samad Khan.]

World of Warcrack

Joichi Ito on the World of Warcraft MMORPG, in Wired:

On November 23, 2004, Rob Pardo and his team at Blizzard Entertainment wrapped up four years of development on World of Warcraft. It quickly became the most popular massively multi-player online game ever, with more than 6 million subscribers each paying up to $15 a month to access its fantastic realms. (At the peak of its popularity, EverQuest had only about half a million subs.)

I started playing a year ago and have become custodian of We Know, a guild of about 250 people worldwide: medics, CEOs, bartenders, mothers, soldiers, students. We assemble in-game to mount epic six-hour raids that require some members to wake at 4 am and others to stay up all night. Outside the game, we stay in touch using online forums, a wiki, blogs, and a mailing list – plus a group voice chat, which I’ve connected to my home stereo so I can hear the guild’s banter while I’m cooking dinner. I have never been this addicted to anything before. My other hobbies are gone. My daily blogging regimen has taken a hit. And my social life revolves more and more around friends in the game.

More here.

History’s Age of Hatred

Tristram Hunt on The War of the World: History’s Age of Hatred by Niall Ferguson, in The Guardian:

Waroftheworld_128His thesis is clear: what makes the 20th century remarkable is its exceptional violence. “The hundred years after 1900 were without question the bloodiest century in history, far more violent in relative as well as absolute terms than any previous era.” Why? Well, not for the old textbook explanations of economic crises, class warfare, nationalism or ideological fervour. Rather, in good historical fashion, for three new reasons.

According to Ferguson, the 20th-century bloodbath was down to the dreadful concatenation of ethnic conflict, economic volatility and empires in decline. Despite genetic advances that revealed man’s essential biological similarities, the 1900s saw wave upon wave of ethnic strife thanks (pace Richard Dawkins) to a race “meme” entering public discourse. Across the world, the idea of biologically distinct races took hold of the 20th century mindset to deadly effect.

More here.

The problems with animal testing

Arthur Allen in Slate:

060601_medex_labmousetnEvery year, in the name of medical progress, scientists breed and nurture hundreds of millions of mice, rats, and other subordinate mammals. Then they expose the critters to substances that could become the next Zocors, Prozacs, and Avastins. Since the alternative is to experiment on people, most everyone other than hardcore animal lovers accepts animal testing. Periodically, however, a spectacular failure raises new questions about the enterprise—not for ethical reasons, but scientific ones.

In March, London clinicians injected six volunteers with tiny doses of TGN1412, an experimental therapy for rheumatoid arthritis and multiple sclerosis that had previously been given, with no obvious ill effects, to mice, rats, rabbits, and monkeys. Within minutes, the human test subjects were writhing on the floor in agony. The compound was designed to dampen the immune response but it had supercharged theirs, unleashing a cascade of chemicals that sent all six to the hospital. Several of the men suffered permanent organ damage, and one man’s head swelled up so horribly that British tabloids refer to the case as the “elephant man trial.”

Animal rights activists in Britain pounced, declaring the uselessness of animal experimentation in the development of human drugs.

More here.

Sydney Biennale

Tracey Clement in the Sydney Morning Herald:

This year’s Sydney Biennale, titled Zones of Contact, is the biggest art exhibition in Australia. Next week 85 leading contemporary artists, from 44 countries as diverse as Lebanon, Latvia, China and Australia will turn Sydney into one big gallery for the next three months. The cutting-edge artworks, more than half made for the Biennale, will be shown in 16 venues from Circular Quay to Blacktown.

Biennale_wideweb__470x3950

The press guff says Zones of Contact is “about the spaces in which people live in and move between, the spatial dimensions of cities, settlements, territories, the land and home”, but really it’s about size.

More here.

Insurance by the Mile

Dean Baker in Harper’s Magazine:

The world must reduce its consumption of fossil fuels in order to avoid the worst effects of global warming. This will require many long-term and expensive measures to promote alternative fuels and conservation—and consequently, many major political battles.

But there is one thing we could do now that would change how people consume gasoline. We could switch from the current way in which people pay for auto insurance to a pay-by-the-mile system. Such a switch might reduce annual gasoline consumption by as much as 10 percent, without raising the cost of insurance for an average driver. The key is to change the way that people view the cost of driving their car.

Currently, auto insurance is viewed as a fixed expense. People pay the same amount for their insurance no matter how much they drive.

More here.

Scientists and thinkers focus their attention on cosmic questions

From The Washington Post:Aging_2

In The Denial of Aging: Perpetual Youth, Eternal Life, and Other Dangerous Fantasies (Harvard Univ., $25.95), Muriel R. Gillick whacks all the major players orchestrating the Last Dance of America’s senior citizens. Medicare is misguided, she argues. Nursing homes are like prisons. Assisted living facilities are too often motivated by greed. Doctors (Gillick is a physician, by the way) are too willing to extend life at any cost. Relatives often have lousy judgment about what’s best for a loved one. Even those facing their own finality are too focused on themselves.

In The View From the Center of the Universe: Discovering Our Extraordinary Place in the Universe (Riverhead, $26.95), the physicist Joel R. Primack and his wife, science philosopher Nancy Ellen Abrams, aim to pick up where Chown leaves off. Primack and Abrams argue that the explosive growth in our understanding of the universe has brought us to the to the brink of a revolution in cosmology similar to the one in physics after Sir Isaac Newton or in biology after Charles Darwin. The barrier, as they see it, is that the scientists leading us in this exploration are generally unwilling to accept the idea that humanity’s desire to make sense of our place in the cosmos is evidence that we are in fact at the center of it all.

Primack and Abrams argue that one of the key findings from science’s exploration of all things great and small is that man is right in the middle of the scale between the largest and smallest things in the universe. Their case is well-argued, if occasionally undermined by the introduction of concepts with fringe-sounding names like Cosmic Uroboros (for the size scale that places man at the center of the universe) and Midgard (the section of that scale where mankind exists). But given their goal of breaking down barriers between the modern and traditional understandings of the universe, the occasional odd-seeming concept is to be expected.

More here.

Have We Met?

From Science:

Magrit_2 We all know that sinking feeling that comes when we just can’t remember someone who clearly recognizes us. So imagine how uncomfortable life might be for a person incapable of recognizing anyone–even a close friend or relative–by face alone. Developmental prosopagnosia, in which an individual has face blindness apparently from birth, was thought to be extremely rare. The first case, in fact, wasn’t diagnosed until 1976. But cognitive neuroscientists Bradley Duchaine of University College London and Ken Nakayama of Harvard University say the condition may be far more common than believed.

Duchaine and Nakayama decided to use the Internet to measure the prevalence of the condition. They recruited individuals for a barrage of psychological tests, including an online facial recognition survey. Some 1600 participants were first given a relatively easy task. They were “introduced” to an individual’s face with pictures flashed on screen for 3 seconds, then presented with three additional photos–one of the prior person and two of other people–and asked to choose the person they had seen before. More difficult tests followed, in which participants were introduced to more faces and then presented with pictures of the same individuals but in different poses in different lighting.

The researchers announced in a press release this week that 2% of their subjects had serious enough problems with face blindness that their daily lives would likely be affected.

More here.

Saturday, June 3, 2006

warming

Over the course of the past century, mean global temperatures increased by .6°C. This change seems slight but isn’t: in the winter of 1905 my great-grandfather, a coppersmith, installed the roof on a new reef-point lighthouse two miles from Lake Michigan’s shore. Each morning he drove out across the open ice in a horse and buggy laden with his copperworking tools; today the water that far from shore never freezes, much less to a depth that could support a horse’s weight.

Well into the 1990s, such changes had happened gradually enough to seem salubrious, at least in the Upper Midwest—a karmic or godly reward, perhaps, for hard work and good behavior. No snow in October! Another fifty-degree day in February! It was as if the weather, too, partook of the national feeling of post-WWII progress: the economy would expand, technology would advance, the fusty mores of a black-and-white era would relax, and the climate, like some index or celebration of all this, would slowly become more mild. This was America. Our children would not only have bigger cars, smaller stereos, a few extra years to find themselves—they’d have better weather, too.

more from n+1 here.

allan kaprow (1927-2006)

Kaprow1

In the late Fifties, the spirit of Dada was revived in Post-World War II American Art. For Allan Kaprow, the artist who led this revival was Jackson Pollock. In a famous article, written in 1956 (the year of Pollock’s death) and published two years later in Art News by the distinguished editor Thomas Hess, Kaprow claimed that Pollock was less important for his paintings as material objects than for the kind of choreographic approach to painting that the artist instigated. This led Kaprow to explore a concept, close to Dada, in which intermedia performances involving groups of participants—which came to be known as “Happenings”—became a new art form. By 1959 Kaprow was exploring a direction in art where idea and process were considered more important than the object. Others, like Jim Dine, Robert Whitman, Claes Oldenburg, and Red Grooms, eventually joined in with their own versions of this phenomenon. In many ways, Kaprow was as much a link between Abstract Expressionism and Pop Art as Rauschenberg, Jasper Johns, or even the sculptor George Segal.

more from The Brooklyn Rail here.

film writing

Jamespan

SINCE all of us are deeply learned experts on the movies even when we don’t know much about anything else, people wishing to make their mark as movie critics must either be able to express opinions like ours better than we can, or else they must be in charge of a big idea, preferably one that can be dignified by being called a theory. In “American Movie Critics,” a Library of America collection drawn from the work of almost 70 high-profile professional critics active at various times since their preferred medium was invented the day before yesterday — the whole history of narrative movies for exhibition still fits inside a mere hundred years — most of the practitioners fall neatly into one category or the other.

It quickly becomes obvious that those without theories write better. You already knew that your friend who’s so funny about the “Star Wars” tradition of frightful hairstyles for women (in the corrected sequence of sequel and prequel, Natalie Portman must have passed the bad-hair gene down to Carrie Fisher) is much less boring than your other friend who can tell you how science fiction movies mirror the dynamics of American imperialism.

more from the NY Times Book Review here.