A billion-year arms race against viruses shaped our evolution

Amy Maxmen in Nature:

VirusViruses and their hosts have been at war for more than a billion years. This battle has driven a dramatic diversification of viruses and of host immune responses. Although the earliest antiviral systems have long since vanished, researchers may now have recovered remnants of one of them embedded, like a fossil, in human cells. A protein called Drosha, which helps to control gene regulation in vertebrates, also tackles viruses, researchers report today in Nature1. They suggest that Drosha and the family of enzymes, called RNAse III, it belongs to were the original virus fighters in a single-celled ancestor of animals and plants. “You can see the footprint of RNAse III in the defence systems through all kingdoms of life,” says Benjamin tenOever, a virologist at Icahn School of Medicine at Mount Sinai in New York and lead author of the paper.

Plants and invertebrates deploy RNAse III proteins in an immune response called RNA interference, or RNAi. When a virus infects a host, the proteins slice the invader’s RNA into chunks that prevent it from spreading. But vertebrates take a different approach, warding off viruses with powerful interferon proteins — while Drosha and a related protein regulate genes in the nucleus. But in 2010, tenOever witnessed an odd phenomenon: Drosha appeared to leave the nucleus of human cells whenever a virus invaded2. “That was weird and made us curious,” tenOever says. His team later confirmed the finding, and saw that Drosha demonstrates the same behaviour in cells from flies, fish and plants. To test the hypothesis that Drosha leaves the nucleus to combat viruses in vertebrates, the researchers infected cells that had been genetically engineered to lack Drosha with a virus. They found that the viruses replicated faster in these cells. The team then inserted Drosha from bacteria into fish, human and plant cells. The protein seemed to stunt the replication of viruses, suggesting that this function dates back to an ancient ancestor of all the groups. “Drosha is like the beta version of all antiviral defence systems,” tenOever says.



Thursday, June 29, 2017

How the superrich have funded a new class of intellectual

David Sessions in The New Republic:

Bf5d2404fb75b37e6817372df3c4db425bed2626Writing in one of Mussolini’s prisons in the 1930s, the Italian Marxist Antonio Gramsci jotted down the fragments that would become his theory of intellectuals. New classes, like the European bourgeoisie after the Industrial Revolution, he proposed, brought with them their own set of thinkers, which he called “organic intellectuals”—theorists, technicians, and administrators, who became their “functionaries” in a new society. Unlike “traditional intellectuals” who held positions in the old class structure, organic intellectuals helped the bourgeoisie establish its ideas as the invisible, unquestioned conventional wisdom circulating in social institutions.

Today, Gramsci’s theory has been largely overlooked in the ongoing debate over the supposed decline of the “public intellectual” in America. Great minds, we are told, no longer captivate the public as they once did, because the university is too insular and academic thinking is too narrow. Such laments frequently cite Russell Jacoby’s The Last Intellectuals (1987), which complained about the post-1960s professionalization of academia and waxed nostalgic for the bohemian, “independent” intellectuals of the earlier twentieth century. Writers like the New York Times columnist Nicholas Kristof attribute this sorry state of affairs to the culture of Ph.D. programs, which, Kristof claims, have glorified “arcane unintelligibility while disdaining impact and audience.” If academics cannot bring their ideas to a wider readership, these familiar critiques imply, it is because of the academic mindset itself.

In his book The Ideas Industry, the political scientist and foreign policy blogger Daniel W. Drezner broadens the focus to include the conditions in which ideas are formed, funded, and expressed. Describing the public sphere in the language of markets, he argues that three major factors have altered the fortunes of today’s intellectuals: the evaporation of public trust in institutions, the polarization of American society, and growing economic inequality. He correctly identifies the last of these as the most important: the extraordinary rise of the American superrich, a class interested in supporting a particular genre of “ideas.”

More here.

What Google searches for porn tell us about ourselves

Sean Illing in Vox:

ScreenHunter_2734 Jun. 29 19.13Two weeks ago, I interviewed Seth Stephens-Davidowitz, author of Everybody Lies, a new book that uses data on America’s Google habits as an insight into our national consciousness.

Two findings from the book dominated the conversation: America is riddled with racist and selfish people, and there may be a self-induced abortion crisis in this country.

But there was plenty more revelatory data in the book that we didn’t cover. So I wanted to follow up with Stephens-Davidowitz to talk about some of the other provocative claims he is making.

I was particularly interested in sexuality and online porn. If, as Stephens-Davidowitz puts it, “Google is a digital truth serum,” then what else does it tell us about our private thoughts and desires? What else are we hiding from our friends, neighbors, and colleagues?

A lot, apparently.

More here.

Physicists have exploited the laws of quantum mechanics to send information without transmitting a signal, but have they, really?

Joshua Roebke in Scientific American:

ScreenHunter_2733 Jun. 29 19.05Quantum mechanics is the consummate theory of particles, so it naturally describes measurements and interactions. During the past few decades, as computers have nudged the quantum, the theory has been reframed to encompass information, too. What quantum mechanics implies for measurements and interactions is notoriously bizarre. Its implications for information are stranger still.

One of the strangest of these implications refutes the material basis of communication as well as common sense. Some physicists believe that we may be able to communicate without transmitting particles. In 2013 an amateur physicist named Hatim Salih even devised a protocol, alongside professionals, in which information is obtained from a place where particles never travel. Information can be disembodied. Communication may not be so physical after all.

This past April, the early edition of a short article about Salih’s protocol appeared online in the Proceedings of the National Academy of Sciences. Most of the article’s 10 authors were members of the University of Science and Technology of China, at its branches in Shanghai and Hefei. The final author was Jian-Wei Pan, an eminent physicist who has also developed a constellation of satellites for communicating through quantum mechanics. He recently used this network for transmitting entangled particles over a distance of 1,200 kilometers.

More here.

My Aunt Had a Dinner Party, and Then She Took Her Guests to Kill 180 Jews

Gili Izikovich in Haaretz:

ScreenHunter_2732 Jun. 29 18.54One morning in April 2007 journalist Sacha Batthyany was approached by an elderly colleague at the Swiss daily where they both worked at the time. The colleague waved a newspaper clipping in front of him. It was an investigative report entitled, “The Hostess from Hell,” published by a German daily.

Glancing at the headline, Batthyany didn’t understand why he was being shown this article, but then he looked at the picture of the hostess and recognized it immediately. It was Margit, his father’s aunt —someone to whom the family demonstrated the utmost respect and also around whom they tended to tread carefully.

So he started to read the piece. In March 1945, it said, just before the end of World War II, Margit held a large party in the town of Rechnitz on the Austrian-Hungarian border to fete her Nazi friends. She, the daughter and heiress of European baron and tycoon Heinrich Thyssen, and her friends drank and danced the night away.

At the height of the evening, just for fun, 12 of the guests boarded trucks or walked to a nearby field, where 180 Jewish slave laborers who had been building fortifications were assembled. They had already been forced to dig a large pit, strip, and get down on their knees. The guests took turns shooting them to death before returning to the party. The organizer of this operation was Margit’s lover Hans Joachim Oldenberg. Margit’s husband, Count Ivan Batthyany, Sacha’s grandfather’s brother, was also at the party.

More here. [Free registration required.]

Ibn Khaldun and The Myth of “Arab Invasion”

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Yves Lacoste over at the Verso blog:

Many contemporary historians and specialists in North African history give the impression that the major interest of Ibn Khaldun's work is that it provides us with a complete explanation of the crisis that put an end to the social and economic development of the Maghreb. They argue that the crisis was the result of the gradual invasion of North Africa by nomadic Arab tribes from the east, first the Beni Hilal and then the Beni Solayn. According to C.A. Julien, the most famous specialist in North African history, the Hilalian invasion was “the most important event of the entire medieval period in the Maghreb.”1 It was, he writes, “an invading torrent of nomadic peoples who destroyed the beginnings of Berber organization — which might very well have developed in its own way and put nothing whatever in its place.”2 It must be stressed at the outset that The Muqaddimah does not provide a systematic account of this crisis, the effects of which were still visible in the fourteenth century. Ibn Khaldun gives no methodical account of the underlying causes of this destructive phenomenon. The Histoire des Berbères describes a series of upheavals and crises, and several unsuccessful attempts to establish a centralized monarchy. But the problem of a Crisis with a capital 'C' is never raised. The Hilalian invasion is not the main theme of the The Muqaddimah. Ibn Khaldun refers to it simply as one of the causes of the turmoil.

The encyclopedic Muqaddimah contains a section on methodology, an analysis of political and social structures, and a general synthesis, but basically it does not describe the spectacular collapse which modern historians claim to have discovered. Ibn Khaldun was not studying a major localized event such as an invasion and its aftermath; he makes no systematic distinction between the character of the Maghreb before and after the crisis. But he does make a methodical analysis of the permanent political and social structures that characterized North Africa. And, according to Ibn Khaldun, the arrival of the Hilalian tribes did not alter those structures to any great extent. No space is given to a detailed study of the Hilalian invasion in the systematic and analytic framework of The Muqaddimah or in the Histoire des Berbères, each chapter of which deals with a different dynasty.

The lengthy modern accounts of the Hilalian invasion do not, therefore, derive directly from Ibn Khaldun. It is, of course, quite legitimate to formulate a thesis by collating scattered data. But the theory that the “Arab invasion” was the determining factor in the crisis of medieval North Africa is less than legitimate, as it takes into account only part of the data provided by Ibn Khaldun.

More here.

Men Can Be So Hormonal

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Therese Huston in the NYT:

Researchers have shown for years that men tend to be more confident about their intelligence and judgments than women, believing that solutions they’ve generated are better than they actually are. This hubris could be tied to testosterone levels, and new research by Gideon Nave, a cognitive neuroscientist at the University of Pennsylvania, along with Amos Nadler at Western University in Ontario, reveals that high testosterone can make it harder to see the flaws in one’s reasoning.

How might heightened testosterone lead to overconfidence? One possible explanation lies in the orbitofrontal cortex, a region just behind the eyes that’s essential for self-evaluation, decision making and impulse control. The neuroscientists Pranjal Mehta at the University of Oregon and Jennifer Beer at the University of Texas, Austin, have found that people with higher levels of testosterone have less activity in their orbitofrontal cortex. Studies show that when that part of the brain is less active, people tend to be overconfident in their reasoning abilities. It’s as though the orbitofrontal cortex is your internal editor, speaking up when there’s a potential problem with your work. Boost your testosterone and your editor goes reassuringly (but misleadingly) silent.

In a classic study conducted at the University of Wisconsin, college students taking final exams rated their confidence about each answer on a five-point scale, “one for a pure guess” and “five for very certain.” Men and women both gave themselves high scores when they answered correctly. But what happened when they’d answered incorrectly? Women tended to be appropriately hesitant, but men weren’t. Most checked “Certain” or “Very certain” when they were wrong, projecting as much confidence for their bad answers as for their good ones.

A Friendship Hiding in the Archives

Scott Schomburg in The Paris Review:

Mitchell-ellisonWorkers wheel Ralph Ellison’s coffin to a vault at the Trinity Church Cemetery on 153rd and Riverside Drive in Manhattan: “There’s no room in the ground to be buried.” His mourners follow the pallbearers out of a small, unadorned chapel. Classical music plays faintly from a cassette player. The vaults, about fifteen feet high, look like “oversized pink marble post office boxes in the sunlight.” The George Washington Bridge is visible in the distance, darkly present in the afternoon haze, like a bridge to a world beyond our own. I’m reading an account of Ralph Ellison’s funeral, nine pages typed, hiding in a folder among the 127 boxes of Joseph Mitchell’s extant papers, at the New York Public Library. There is no byline, and it isn’t Mitchell’s prose. I stumble on it during my third day in the archives, sitting under lamplight at a corner desk in the Brooke Russell Astor Reading Room. Mitchell and Ellison’s friendship has never been documented, as far as I know, but here in the preserved debris of Mitchell’s life, Ellison fills an entire folder. Four, in fact. I keep reading: “The ceremony is perfunctory, and except for watching Joe Mitchell comfort Mrs. Ellison, his arms encircling her small body, his sorrowful face bent toward hers, you almost forget someone has died.”

Last March, during the second of six trips to the library, I spent a week reading Mitchell’s papers, attending to the details he also felt drawn to when assembling his portraits, the “scraps and crumbs and odds and ends and bits and pieces.” Mitchell’s stories reveal a writer who had little use for the spectacle at the center of things; he looked in the city’s shadows and at its dark edges for companions who reflected his own attitude toward life and death. So I began by following his threads, wondering if the truth of his life would be found beyond or beneath or adjacent to the legend that has grown up around him, in some as yet unexplored place or with the people surrounding his life—not only in the bound volumes of his work, but in his notes and collected objects, discarded things sacred only to him. My father joined me in the archives to help take photos, and I came back to Durham, North Carolina, with more than nine thousand images, including a photo for every page of Mitchell’s diary notes, all twenty boxes of them.

More here.

Scientists produce dialysis membrane made from graphene

From Phys.Org:

Materialcanf"Because graphene is so thin, diffusion across it will be extremely fast," Kidambi says. "A molecule doesn't have to do this tedious job of going through all these tortuous pores in a thick membrane before exiting the other side. Moving graphene into this regime of biological separation is very exciting." Dialysis, in the most general sense, is the process by which molecules filter out of one solution, by diffusing through a membrane, into a more dilute solution. Outside of hemodialysis, which removes waste from blood, scientists use dialysis to purify drugs, remove residue from chemical solutions, and isolate molecules for medical diagnosis, typically by allowing the materials to pass through a porous membrane.

Today's commercial dialysis membranes separate molecules slowly, in part due to their makeup: They are relatively thick, and the pores that tunnel through such dense membranes do so in winding paths, making it difficult for target molecules to quickly pass through. Now MIT engineers have fabricated a functional dialysis membrane from a sheet of graphene—a single layer of carbon atoms, linked end to end in hexagonal configuration like that of chicken wire. The graphene membrane, about the size of a fingernail, is less than 1 nanometer thick. (The thinnest existing memranes are about 20 nanometers thick.) The team's membrane is able to filter out nanometer-sized molecules from aqueous solutions up to 10 times faster than state-of-the-art membranes, with the graphene itself being up to 100 times faster. While graphene has largely been explored for applications in electronics, Piran Kidambi, a postdoc in MIT's Department of Mechanical Engineering, says the team's findings demonstrate that graphene may improve membrane technology, particularly for lab-scale separation processes and potentially for hemodialysis.

More here.

Wednesday, June 28, 2017

The New Working Class

Gabriel Winant in Dissent:

1498578945AronoffpplB4pollutersNYSNA666When I teach history classes, I often give students assignments that ask them to—as we say in the profession—“historicize” themselves. At a superficial level, it’s easy to absorb this fundamental insight of historical scholarship: that an individual’s ideology doesn’t come from inside them, but is an effect of time and place. But it’s much easier to understand how this was true of some stranger in the distant past than to accept it about yourself—that you’re a product of the social processes of your time, and your ideas are not crystals of pure rationality, but the residue of these processes.

Much of the indictment of mainstream journalists and politicians on the center-left boils down to this problem. The leaders of the Democratic Party and their loyalists seem to hear themselves as the sole voice of reason in an insane moment. They don’t grasp that they’re speaking a particular and provincial language—the institutional formalism and propriety of the professional middle class of the late twentieth century—and even less why that language enjoys less resonance now than in its 1990s heyday. The latest defeat—that of Jon Ossoff in the Georgia special election—illustrates this dynamic starkly: Democrats are sniffing for suburban votes where they can’t get a majority, while ignoring the people who might actually want to vote for them. The party appears committed to offering substantively vacuous defenses of formalism to an electorate whose dire needs have destroyed lingering faith in our residual institutional norms. Ossoff, who ran on a promise not to send impulsive tweets and studiously avoided actual policy discussions, embodies the problem: reasonability offered as the rationale for the Democrat, but no actual reasons. Conceding the election, the losing candidate delivered his speech in an imitation-Obama style. The principle of neoliberal governance—democratic politics as mere theater, markets as the real governors—became literal here: the Democrats banked their hopes on someone pretending to be a politician on the TV.

More here. [Thanks to Corey Robin.]

A Path Less Taken to the Peak of the Math World

Kevin Hartnett in Quanta:

ScreenHunter_2730 Jun. 28 22.46On a warm morning in early spring, June Huh walked across the campus of Princeton University. His destination was McDonnell Hall, where he was scheduled to teach, and he wasn’t quite sure how to get there. Huh is a member of the rarefied Institute for Advanced Study, which lies adjacent to Princeton’s campus. As a member of IAS, Huh has no obligation to teach, but he’d volunteered to give an advanced undergraduate math course on a topic called commutative algebra. When I asked him why, he replied, “When you teach, you do something useful. When you do research, most days you don’t.”

We arrived at Huh’s classroom a few minutes before class was scheduled to begin. Inside, nine students sat in loose rows. One slept with his head down on the table. Huh took a position in a front corner of the room and removed several pages of crumpled notes from his backpack. Then, with no fanfare, he picked up where he’d left off the previous week. Over the next 80 minutes he walked students through a proof of a theorem by the German mathematician David Hilbert that stands as one of the most important breakthroughs in 20th-century mathematics.

Commutative algebra is taught at the undergraduate level at only a few universities, but it is offered routinely at Princeton, which each year enrolls a handful of the most promising young math minds in the world. Even by that standard, Huh says the students in his class that morning were unusually talented. One of them, sitting that morning in the front row, is the only person ever to have won five consecutive gold medals at the International Mathematical Olympiad.

More here.

ISLAM & THE IMAGINATION: NOTES FROM AN AMERICAN ARTIST IN THE 21ST CENTURY

Zain Alam in The Miami Rail:

Image0012-768x1334I am a Muslim. Minutes after I was born at the Flushing Hospital in Queens, New York City, my father whispered the shahadah into my ears: La ilaha il-Allah—There is no God but God. I was introduced to Islam with the world, and the rhythm of La ilaha il-Allah took the place of my mother’s heartbeat. All other experiences were subsequent to the rhythms of Islamic verse. In my childhood home of Kennesaw, Georgia and in cities across South Asia, I’ve heard the shahadah repeated daily in the azaan, which calls believers to prayer. No one disputes the beauty of the sound—the strong and sonorous voice of the muezzin casting a spell on its surroundings. At home, recorded azaans are played back by apps that have re-placed miniature mosque-shaped alarm clocks that double as home decorations. But their intention is the same: to invite us to prayer regularly, five times a day.

I am a musician. My songs take on new lives apart from me the moment they are shared. The long process of songwriting is how I try to do justice to what begins as a melody in a dream. My task as a composer is simply to submit to the dream, guiding it to structure and feeling it into form, through a private intuition that is informed by deep traditions. I may not know why singing songs—even when I’m alone—brings me such pleasure, but sharing them with others comes from a desire to make something that can find a life far beyond my own.

More here.

No, you’re not entitled to your opinion

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Patrick Stokes in The Conversation:

Every year, I try to do at least two things with my students at least once. First, I make a point of addressing them as “philosophers” – a bit cheesy, but hopefully it encourages active learning.

Secondly, I say something like this: “I’m sure you’ve heard the expression ‘everyone is entitled to their opinion.’ Perhaps you’ve even said it yourself, maybe to head off an argument or bring one to a close. Well, as soon as you walk into this room, it’s no longer true. You are not entitled to your opinion. You are only entitled to what you can argue for.”

A bit harsh? Perhaps, but philosophy teachers owe it to our students to teach them how to construct and defend an argument – and to recognize when a belief has become indefensible.

The problem with “I’m entitled to my opinion” is that, all too often, it’s used to shelter beliefs that should have been abandoned. It becomes shorthand for “I can say or think whatever I like” – and by extension, continuing to argue is somehow disrespectful. And this attitude feeds, I suggest, into the false equivalence between experts and non-experts that is an increasingly pernicious feature of our public discourse.

Firstly, what’s an opinion?

Plato distinguished between opinion or common belief (doxa) and certain knowledge, and that’s still a workable distinction today: unlike “1+1=2” or “there are no square circles,” an opinion has a degree of subjectivity and uncertainty to it. But “opinion” ranges from tastes or preferences, through views about questions that concern most people such as prudence or politics, to views grounded in technical expertise, such as legal or scientific opinions.

You can’t really argue about the first kind of opinion. I’d be silly to insist that you’re wrong to think strawberry ice cream is better than chocolate. The problem is that sometimes we implicitly seem to take opinions of the second and even the third sort to be unarguable in the way questions of taste are. Perhaps that’s one reason (no doubt there are others) why enthusiastic amateurs think they’re entitled to disagree with climate scientists and immunologists and have their views “respected.”

More here.

Visualizing the global income distribution

Arun Jayadev at the OUP Blog:

The evolution of the distribution of income among individuals within countries and across the world has been the subject of considerable academic and popular commentary in the recent past. Works such as Thomas Piketty’s Capital in the 21st Century or Joseph Stiglitz’s The Price of Inequality have become unlikely bestsellers, garnering a startling degree of both academic and popular interest.

The last few decades have seen a sharp increase in global integration with its attendant benefits and anxieties. Concerns about the distributional effects of cross-border flows of trade and finance have grown and are central issues in political debates worldwide. At the same time, massive global inequities, dysfunctional polities, and the most egregious outcrops of these-civil breakdowns and mass migration have become the staple of mass media.

Also in the last couple of decades, for the first time in human history, we have the raw materials to measure the living standards of individuals across the world in comparable terms. The careful collection of survey information from almost every country in the world, led by national statistical offices and multilateral organizations, and the simultaneous collation and harmonization of price data by the International Comparison Project has made it possible, in principle, to truly understand and compare the fortunes of individuals in any country or region in the world with others from elsewhere.

Figure 1 (using data drawn from the Global Consumption and Income Project) provides a simple snapshot of the distribution of income. The height of the ‘skyscrapers’ represent average incomes in purchasing power (PPP) terms in 2005 for each population decile for over 150 countries in the year 2014. That is the height of each building represents the average income in 2014 in dollars for 10% of the population of a country, correcting for the fact that prices differ across countries. The height of each bar in the chart varies along two axes: the first, the horizontal axis is a ranking of countries from the poorest (the Democratic Republic of Congo) on the left of the figure to the richest (Luxembourg) on the right; the second, from the front to the back of the figure, shows the distribution of income from poorest to richest within each country. Note that the skyscrapers for some countries such as India and China are wider. This indicates their relatively large size of population.

Figure-1-CORE
Figure 1: average income of each decile of the population, $2005 PPP terms in 2014. Image by CORE, used with permission

As is evident, most of the ‘mass’ of income is on the right-hand side and at the back, indicating that most of world income is held by the rich in the rich countries. A relatively rich US individual sitting on his income skyscraper looks down on a world that is very far below him in terms of living standards.

More here.

From religious reflection to mummy vlogs: diaries through the ages

John Mullan in New Statesman:

DiaryWhy keep a diary? An absorbing and sometimes droll new exhibition in London surveys the history of diary-keeping, particularly over the past century, and gives sometimes contradictory answers to this question. It is a collaboration between the Centre for Life-Writing Research at King’s College and the Great Diary Project, the latter dedicated to rescuing and archiving a growing collection of diaries. The emphasis is on “ordinary” diarists, and on the ways in which keeping a diary has been changing over recent decades. In earlier centuries, the point of ­keeping a diary was to give a minute account of yourself to God. Diary-keeping was closely related to the growth of Protestantism. No wonder that those Protestant protagonists of 18th-century novels, Daniel Defoe’s Robinson Crusoe and Samuel Richardson’s Pamela, take so readily to diaries. Self-recording signalled religious self-inspection. The purpose remained powerful even as religious devotion waned. When he recommended logging 13 virtues a day, Benjamin Franklin was attempting an ­Enlightenment version of this. When he recorded his whoring as well as his intellectual conversations, James Boswell was not only boasting, but also puzzling over his own sinful nature.

Diary-keeping was therefore a discipline. Samuel Johnson recorded his need for a diary in order “to methodise my life, to resist sloth”. But then he never did it. This exhibition shows the uninitiated how diary apps can now make that struggle with sloth much easier. Sign yourself up, and the software will weave information about your whereabouts, the weather and contemporary events into your record. Just a few words from you can make an entry look rich. Modern diary-writers can bring to the form some of the self-seriousness that was quite proper in an earlier, religious age. A magnificently solemn quotation from Susan Sontag adorns one of the walls. “I know I’m alone, that I’m the only reader of what I write here,” she announces – to ­herself. “. . . I feel stronger for it, stronger each time I write something down.” Among the handful of celebrity diarists whose work is on show, the actor Kenneth Williams has something of the fierce purpose of self-investigation. A few pages of his copious journals display, in his appropriately fastidious script, his social unease, his frequent ennui and his fascination with his every physical ailment.

More here.

How quantum trickery can scramble cause and effect

Philip Ball in Nature:

GiphyAlbert Einstein is heading out for his daily stroll and has to pass through two doorways. First he walks through the green door, and then through the red one. Or wait — did he go through the red first and then the green? It must have been one or the other. The events had have to happened in a sequence, right? Not if Einstein were riding on one of the photons ricocheting through Philip Walther's lab at the University of Vienna. Walther's group has shown that it is impossible to say in which order these photons pass through a pair of gates as they zip around the lab. It's not that this information gets lost or jumbled — it simply doesn't exist. In Walther's experiments, there is no well-defined order of events.

This finding1 in 2015 made the quantum world seem even stranger than scientists had thought. Walther's experiments mash up causality: the idea that one thing leads to another. It is as if the physicists have scrambled the concept of time itself, so that it seems to run in two directions at once. In everyday language, that sounds nonsensical. But within the mathematical formalism of quantum theory, ambiguity about causation emerges in a perfectly logical and consistent way. And by creating systems that lack a clear flow of cause and effect2, researchers now think they can tap into a rich realm of possibilities. Some suggest that they could boost the already phenomenal potential of quantum computing. “A quantum computer free from the constraints of a predefined causal structure might solve some problems faster than conventional quantum computers,” says quantum theorist Giulio Chiribella of the University of Hong Kong. What's more, thinking about the 'causal structure' of quantum mechanics — which events precede or succeed others — might prove to be more productive, and ultimately more intuitive, than couching it in the typical mind-bending language that describes photons as being both waves and particles, or events as blurred by a haze of uncertainty. And because causation is really about how objects influence one another across time and space, this new approach could provide the first steps towards uniting the two cornerstone theories of physics and resolving one of the most profound scientific challenges today. “Causality lies at the interface between quantum mechanics and general relativity,” says Walther's collaborator Časlav Brukner, a theorist at the Institute for Quantum Optics and Quantum Information in Vienna, “and so it could help us to think about how one could merge the two conceptually.”

More here.

Tuesday, June 27, 2017

Kumail Nanjiani and Emily V. Gordon Turned Their Life Into a Rom-Com

Julia Felsenthal in Vogue:

00-lede-the-big-sickThe comedian Kumail Nanjiani was a teenager in his native Pakistan when he first fell madly, deeply in love with the movie Four Weddings and a Funeral. Around the same time and several large bodies of water away in North Carolina, the writer Emily V. Gordon was cultivating a lifelong affection for films like Say Anything, Heathers, and Raising Arizona. It wasn’t until they were both in their late twenties and living in Chicago that the pair met at one of Nanjiani’s stand-up shows, embarked on an uncertain affair (she was newly divorced; his strict Muslim parents expected that he’d marry a Pakistani woman), and eventually wed, but only after Gordon came down with a mysterious, life-threatening illness that landed her in the hospital in a medically induced coma for eight terrifying days. (In the end she was diagnosed with a manageable but rare adult-onset autoimmune disorder called Still’s disease.)

Later this summer, the couple will celebrate their 10th wedding anniversary. And for exactly half their marriage, they’ve been working together on The Big Sick, a romantic comedy that they cowrote and based (with artistic license) on their real love story. In the film, Kumail (played by Nanjiani) and Emily (played by Zoe Kazan) meet cute at a comedy club (she heckles him on stage), start sleeping together casually, and against their better judgment, begin to fall for each other. But then Emily discovers that Kumail has a cigar box full of photos of Pakistani women—possible matches in the arranged marriage his parents (Zenobia Shroff and Bollywood star Anupam Kher) intend to broker for him. (Kumail:”Do you know what we call arranged marriage in Pakistan? Marriage!”) They break up, she falls ill, a friend alerts Kumail, and he’s the only one present when the doctors need a signature authorizing them to put his ex-girlfriend into a coma. For the latter half of the film, she lays unconscious as Kumail holds vigil at her bedside, works his feelings out in an abysmal stand-up set, bonds with her bereft parents (Holly Hunter and Ray Romano), and questions how willing he is to risk his relationship with his own family for a girl he may already have let slip through his fingers.

More here.

Check out this video of a younger Kumail, it is less than two minutes long:

William Deresiewicz explains how an elite education can lead to a cycle of grandiosity and depression

Lauren Cassani Davis in The Atlantic:

Lead_largeThe former Yale English professor William Deresiewicz stirred up quite a storm earlier this month with his New Republic essay “Don’t Send Your Kid to the Ivy League”—a damning critique of the nation’s most revered and wealthy educational institutions, and the flawed meritocracy they represent. He takes these arguments even further in his upcoming book, Excellent Sheep: The Miseducation of the American Elite and the Way to a Meaningful Life. Part cultural commentary, part philosophical treatise on the meaning of education itself, the book reads like a self-help manual for ambitious yet internally adrift adolescents struggling to figure out how to navigate the college system, and ultimately their own lives. Deresiewicz, who is also the author of A Jane Austen Education: How Six Novels Taught Me About Love, Friendship and the Things That Really Matter, spoke to me on the phone from his home in Portland, Oregon.

Lauren Cassani Davis: How does the phrase “excellent sheep” describe the typical student at an elite college today?

William Deresiewicz: The most interesting thing about that phrase is that I didn’t write it myself. It came out of the mouth of a student of mine, and just seemed perfect. They’re “excellent” because they have fulfilled all the requirements for getting into an elite college, but it’s very narrow excellence. These are kids who will perform to the specifications you define, and they will do that without particularly thinking about why they’re doing it. They just know that they will jump the next hoop.

Davis: Do you see a connection between this “hoop-jumping” mindset and other trends, like mental-health issues, on college campuses?

Deresiewicz: The mental-health issues, absolutely. People have written books about this—adolescent therapists like Madeline Levine, who wrote The Price of Privilege. These students are made to understand that they have to be perfect, that they have to do everything perfectly, but they haven’t turned to themselves to ask why they’re doing it. It’s almost like a cruel experiment with animals that we’re performing—every time the red light goes on, you have to push the bar. Of course they’re stressed.

This is also why they’re sheep, because they have never been given an opportunity to develop their ability to find their own direction. They’re always doing the next thing they’re being told to do.

More here.