What We Get Wrong About Drugs Like Ozempic

Yoni Freedhoff in Time:

Imagine a new medication was developed that not only provided meaningful improvement for the debilitating chronic condition it’s prescribed, but also helps to treat and prevent a myriad of other serious diseases. Imagine this same drug markedly improved a person’s quality of life with noted reductions in pain and improvements in mobility along with increases in confidence and mood. Now imagine that the media and medical coverage of its release are almost uniformly negative or sensationalistic.

This is precisely what has happened with the new generation of anti-obesity medications, that began with Wegovy/Ozempic and with many more rapidly on their way. Currently approved medications lead people with obesity to lose on average 15% of their body weight which in turn has dramatic benefits for multiple weight responsive medical conditions, including diabetes, high blood pressure, sleep apnea, GERD, fatty liver disease, and more. Clinical trials of newer molecules demonstrate even greater losses with the most recent, for Retatrutide, demonstrating a 24% body weight loss after 48 weeks of use and where weight in those participants appeared to still be dropping. Sustained weight loss has been shown to decrease the risk of developing those same conditions as well as some of our most common cancers including breast, uterine, and colon.

More here.