From Scientific American:
By a simple food-in/energy-out model, a run on the treadmill or swim in the pool should make you want to eat more. But recent findings have suggested that exercise can actually help to slow overeating. And a new study presents evidence that the body's physiologic response to exercise can help retune the nervous system's cues and make the body feel less hungry, rather than more so. Hunger is a complex sensation, but it is determined in part by neurons located in the hypothalamus, which send signals to the brain telling it that you're either hungry or sated. Those neurons get their message from hormones, including insulin and leptin. When the body develops a resistance to these messengers, people become more prone to overeating and weight gain. And scientists have begun to suspect that cellular inflammation might be at least partly responsible for allowing these signals to get out of whack.
Researchers behind the new work found that “physical activity reorganizes the set point of nutritional balance through anti-inflammatory signaling,”