Aging mice given blood plasma from young humans regain youthful attributes

From Phys.Org:

A team of researchers working at a company called Alkahest has reported at this year's Society for Neuroscience annual meeting that injections of blood plasma from young human beings caused aging mice to regain some youthful attributes. Company representative Sakura Minami claimed that testing with mice given youthful human plasma led to improved cognition in middle-aged mice. She has also spoken to the media regarding the experiments and results conducted by the company.

Prior research has shown that if an older mouse physically shared a blood system with a younger, that the older mouse would become rejuvenated while the younger mouse would take on symptoms of aging. Other studies have shown that simply injecting older mice with younger mouse plasma also had rejuvenating effects. Now, in this new study, the researchers claim the same to be true for blood plasma from young humans. The study consisted of injecting year old (middle-aged) mice with plasma from human teenagers. The mice were injected with the plasma twice a week for three weeks and were then subjected to tests (including a Barnes maze) that have been designed to test their mental abilities. Minami claims that the treated older mice scored close to young mice on the tests, suggesting they had undergone mental rejuvenation. She reported that the company had also studied portions of the brains of the treated mice—specifically the hippocampus, which is known to be involved in learning and memory—and found signs of neurogenesis.

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