Michael Marshall in Nature:
From hot springs to DNA forensics
In the summer of 1966, while he was an undergraduate at Indiana University, Hudson Freeze went to live in a cabin on the edge of Yellowstone National Park. He was working for microbiologist Thomas Brock, who was convinced that certain microorganisms were living at surprisingly high temperatures. Dodging bears, and the traffic jams they caused, Freeze visited the hot springs every day to sample their bacteria. On 19 September, Freeze succeeded in growing a sample of yellowish microbes from Mushroom Spring. Under a microscope, he found an array of cells collected from the near-boiling fluids. “I was seeing something that nobody had ever seen before,” says Freeze, now at the Sanford Burnham Prebys Medical Discovery Institute in La Jolla, California. “I still get goosebumps when I remember looking into the microscope.”
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A writer explores the semiotic. All artists work with signs and meanings. For me, writing is a form of semiotic sabotage. It is full of bold advances and strategic retreats, and above all it is shot through with deliberate acts of obstructionism.
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When Robert Hooke gazed through his microscope at a slice of cork and coined the term ‘cell’ in 1665, he was really looking at just the walls of the dead cells. The squishy contents typically found within would become objects of ongoing study. But for many plant scientists, the walls themselves faded into the background. They were considered passive containers for the exciting biology inside.
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