Newly discovered link between traumatic brain injury in children and epigenetic changes

From The Conversation:

newly discovered biological signal in the blood could help health care teams and researchers better understand how children respond to brain injuries at the cellular level, according to our research in the Journal of Neurotrauma.

In the future, this information could help clinicians identify children who need more tailored follow-up care after a traumatic brain injury. As part of our work as a nurse scientist and neuropsychologist studying traumatic brain injury, we wanted to look for biological markers inside cells that might help explain why some children recover smoothly after brain injury while others struggle. To do this, we focused on DNA, the instruction manual of cells. DNA is organized into regions called genes, each of which codes for proteins that carry out different functions like repairing tissues. While your DNA generally stays the same throughout your life, it can sometimes collect small chemical changes called epigenetic modifications. These changes act like dimmer switches, turning genes up or down without changing the underlying code. In general, dialing up the activity of a gene increases production of the protein it codes for, while dialing down the gene decreases production of that protein.

More here.

Enjoying the content on 3QD? Help keep us going by donating now.