Deanna MacNeil in The Scientist:
In solid cancers, cellular behaviors such as motility and invasiveness are well characterized contributors to poor prognosis and cancer spread. Scientists pay close attention to a process called epithelial to mesenchymal transition (EMT) in solid cancers, as this transformation primes malignant cells for metastasis. However, EMT is somewhat of an enigma for blood and lymphatic cancers, which originate from cells that already freely circulate in the body before becoming malignant. Although conventional EMT transcription factors are often differentially expressed in leukemias and lymphomas, their oncogenic role remains unclear in different hematopoietic contexts.
More here.