We need to talk about systematic fraud

Jennifer Byrne in Nature:

From where I work at the University of Sydney, you cannot see the ocean. However, in Australia, the ocean is part of our national consciousness. This is perhaps why I think of the research literature as an ocean, linking researchers in disparate yet ultimately connected fields. Just as there is growing alarm about our rising, polluted oceans, scientists are increasingly talking about the swelling research literature and its contamination by incorrect research results.

Most of the talk centres on unconscious bias and ill-informed sloppiness; conversations about intentional deception are more difficult. Unlike most faulty research practices, fraud actively evades detection. It is also overlooked because the scientific community has been unwilling to have frank and open discussions about it.

In 2015, I discovered several papers had been written about a gene that I and my colleagues first reported in 1998. All were by different authors based in China, but contained shared and strange irregularities. They also used highly similar language and figures. I think the papers came from third parties working for profit, fuelled by the pressure on authors to meet unrealistic publication expectations. (Such operations have been identified by investigative journalists.) I also think that, with most of the protein-coding and non-protein-coding genes in the human genome currently understudied, such third parties are targeting less-well-known human genes to produce low-value and possibly fraudulent papers.

How could such manuscripts slip through peer review?

More here.