Robert McCrum in The Guardian:
Wolfe is an accidental sleuth. Her scholar’s passion is as much for old manuscripts as for the obscurities surrounding our national poet. Project Dustbunny, for example, one of her initiatives at the Folger Shakespeare Library, has made some extraordinary discoveries based on microscopic fragments of hair and skin accumulated in the crevices and gutters of 17th-century books.
DNA forensics aside, Wolfe’s role as a curator at the Folger is to bring her expertise to bear on the tantalising mass of documents that survives from the late 16th century. And yet, despite a heap of legal, commercial and matrimonial evidence, Shakespeare the man continues to slip through scholars’ fingers. Four centuries after his death, apart from a handful of crabbed signatures, there is not one manuscript, letter or diary we can definitively attribute to the poet, sponsoring the pervasive air of mystery that surrounds his genius. Indeed, the most intimate surviving Shakespeare document remains that notorious will, in which he bequeathed his wife his “second best bed”.
Before Wolfe arrived on the scene, all that scholars could be certain about was that a man named Shaxpere, Shaxberd or Shakespear was born in Stratford in 1564, and that he was an actor whose name is printed in the collected edition of his work published in 1623. We also know that he married Anne Hathaway, and died in 1616, according to legend, on his birthday, St George’s Day. The so-called “Stratfordian” case for Shakespeare rested on these, and a few other facts, but basically, that was it.
More here.