Obesity

Tony Scully in Nature:

CoverFor a condition as prevalent and dangerous as obesity (see page S50), we know surprisingly little about its causes and cures. We have much to learn about how fat tissue stores and burns lipids; there may even be new types of human fat cell yet to be discovered (S52). And although it is clear that the types of microbe living in the gut correlate with body weight, we do not know whether changes in these populations are a cause of weight gain, or a consequence (S61).

The best way to lose weight is to eat less and exercise more. But as a strategy to combat obesity at the population level, this common-sense prescription is proving ineffective over the long term. Tailored treatment programmes that factor in the stresses and temptations of the real world, using insights from behavioural research, are showing some success. Drugs may also form part of the solution (S54). Or perhaps the pharmaceutical option should be a last resort, and society should instead use the power of government regulation to encourage healthier lifestyle options (S57). Of course, obesity does not result from the environment alone — it is one of our most strongly genetically influenced traits. Scores of genes have been implicated, but the evidence suggests that something other than genes accounts for whether someone is likely to become obese (S58). Controlling appetite is not just a matter of will power; much of our dietary behaviour is hardwired. Neuroscientists are using new techniques to map the neural circuits that control when and how much we eat (S64). But these appetite systems, which evolved to ensure we have enough of the right nutrients, are now being subverted by modern food processing (S66).

More here.

The Shadow of Militant Ideology over Islam

by Ahmed Humayun

The causes of contemporary militancy in Muslim majority societies are many and complex, but one of the important factors is a virulent ideology that glorifies violence as a means to achieve political and religious ends. This ideology draws upon various historical inspirations—some Islamic and some Western, some local and some global—and can boast intellectuals, activists, and propagandists operating across different Muslim cultures and languages.

My concern here is not in tracing out the intellectual history of militant ideology. Nor am I seeking to precisely determine the importance that can be placed on ideology relative to other factors—a partial list of which might include a particular interpretation of Islamic doctrines about just war, the colonial legacy, the repression and failures of the authoritarian modern state, the consequences of the Shia Islamic revolution in Iran and the corresponding Sunni reaction in Saudi Arabia, Western alliances with authoritarian Muslim states or occupations of Muslim lands, and the systemic tendency of a wide range of states to utilize militant groups as proxies to advance their narrow interests. I am interested instead in exploring some of the consequences of militant ideology for Muslim societies today.

There is a tendency in the West to primarily view the activities of militant Islamist groups from the perspective of the danger that they pose to Western homelands. This is natural as a matter of pragmatic policy and national interest. Cataclysmic events like 9/11 in the United States or 7/7 in Britain have underscored the fact that the element of anti-Westernism in militant ideology is deeply ingrained. And yet it is clear that the greatest danger of militant ideology is posed to Muslims living in Muslim majority societies. This can be seen in the endless, gruesome wave of violence that has yielded enormous death tolls in recent years, mostly civilian, in countries as varied as Afghanistan and Pakistan, Iraq and Yemen, and many other places besides. (In Pakistan alone, militant violence may have claimed as many as forty to fifty thousand lives since September 11th).

As the drawdown of Western military forces from Muslim lands proceeds—Iraq having been vacated, and the withdrawal from Afghanistan imminent—the level of danger seems greater than ever. Militant groups show no signs of disbanding once Western military forces depart (though that departure may weaken the force of some militant arguments, and is therefore a positive development). Instead, militant ideas that emphasize the use of slaughter to advance political and religious change, and that target minorities and Muslims deemed beyond the pale of Islam—that is, the overwhelming majority of them—is on the rise. Militant ideology can boast many more factions today than it did on September 11th, with hundreds of them fueling sustained campaigns of terrorism and insurgency, and a general resistance to state authority, across the Middle East and South Asia.

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From Cell Membranes to Computational Aesthetics: On the Importance of Boundaries in Life and Art

by Yohan J. John

6a019b010d0685970b01a511a3baa9970c-320wiNo one knows exactly how life began, but a pivotal chapter in the story was the formation of the first single-celled organism — the common ancestor to every living thing on the planet. I like to think of the birth of life as the creation of the first boundary — the cell membrane. That first cell membrane enclosed a drop of the primordial soup, creating a separation between inside and outside, and between life and non-life. Through this act of individuation the cell could become a controlled environment: a chemical safe zone for the sensitive molecular machinery needed to maintain integrity and facilitate replication. The game of life consists in large part of perpetuating the difference between inside and outside for as long as possible. Death, then, is the dissolution of difference. But the paradox at the heart of life is that the inside cannot survive without the outside. The cell requires raw materials — nutrients and energy — to sustain itself and to reproduce, and these must be sought outside the safe zone, in the wild and unpredictable outside world.

The cell membrane has a dichotomous role. It must preserve the cell’s identity as an entity that is distinct from everything outside it, but it must not be an impenetrable wall. It must be a gateway through which the cell can absorb raw material and eject waste, but it cannot allow the inside to become inundated by the outside. It fulfills this challenge by being selectively permeable, carefully overseeing the traffic between the inside and the outside. The cell membrane must also be flexible, because it serves the roles of locomotion and consumption. In a single-celled organism, the cell membrane is therefore a primitive sense organ, a transportation system and a digestive system, all rolled into one.

The birth of life was a moment of cleaving: when the first cell membrane enveloped its drop of primordial ooze, it cleaved the inside from the outside, but it also became the conduit through which the inside could cleave to the outside. Like Janus, the two-faced Roman god of beginnings and endings, of doors and passageways, the cell membrane is a sentry looking in two directions simultaneously. Given its role in cellular transaction, transition and transformation, the cell membrane’s function might even be described as a precursor to intelligence.

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My Genome Report Card

by Carol A. Westbrook

Less than 100,000 people in the entire world have had their genome sequenced. I am now one of them. As I wrote in 3QuarksDaily in December, I went into this with some trepidation–you never know what bad news lurks in your genome! I promised to give a report of my results, and here it is.

To get my genome sequenced, I enrolled in Illumina's “Understand Your Genome” Program. Illumina is one of the few companies licensed by the FDA to perform whole genome sequencing (WGS) for medical diagnosis–other consumer products such as Ancestry.com, National Geographic's Geno 2.0, and 23andMe, provide only a limited analysis. I sent in a blood sample in November, and in February received a detailed analysis by Illumina's genetic counselors. In March I attended the “Understand Your Genome,” conference, where I received an iPad with my WGS uploaded into the “MyGenome” app, training on the use of the app, and a fascinating daylong seminar which explored the interpretation and medical uses of genome sequences. My daughter, a medical student, attended the program with me.

Viewed on the iPad, my genome sequence consists of two similar but not identical, parallel lines of the letters, one from each chromosome. There are only 4 letters, A,C,G, and T, representing the four DNA nucleotides that are aligned to make the sequence. A human sequence is about 6 billion nucleotides long, with half inherited from one parent and half from the other, and a few new mutations that arose on their own, probably less than 100. Thus, from a family perspective, a person's DNA sequence is 50% identical to each of his parents, children or siblings, 25% identical to grandparents, grandchildren, and so on to my distant relatives. My genome is very similar to every other person's, but it is not identical to anyone's. No one has ever had the same DNA as me, and never will — it is what makes me uniquely me.

How different am I from everyone else? My genetic analysis showed that I have 3,524,186 individual nucleotide differences, from the “average” genome to which it was compared, reference genome hg19, NCBI build 37. This is about 0.05% variation, which is typical for most people. To put this in perspective, if you were to compare my DNA to that of our two most closely-related primate species, bonobos and chimpanzees, the differences would be over 4%; when comparing me to Neanderthal man, however, you would find only 0.3% variation. So 0.05% is small enough to make me human, but large enough to make me a unique individual.

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How to Fall

by Tamuira Reid

Duck into the nearest bar, grab a stool, roll-up your sleeves. Get down to business. Take a shot. Take another. Take a third. Drink a glass of wine, a glass of beer, a glass of vodka. Rinse. Repeat. You remember how to do this. A pro never forgets.

You should call your sponsor but you won't. You should probably feel guilty but you don't.

Drink with the ones who have nothing to lose because they've lost everything already. Or maybe they never had anything to begin with. Some people are dealt a shit hand in life. You are not one of them. You had it all and fucked-it up.

It doesn't matter if you have seven hours or seven months or seven years. IT is always there, waiting. Disguised as a good time. A giant Band-Aid. The best lay of your life. Up the five flights of stairs to your studio in Harlem, or your loft in Soho, or in the family room of your green-shuttered craftsmen in Stamford. Right behind you.

The anticipation is over. The “what if” becomes the “what now”. You drink and drink and drink until body and mind unravel and you want nothing and feel nothing and coming undone like this is better than air. It's better than life. It's better.

Across town your family is getting ready for the party. Pink balloons hang from streamers stretched across doorways. Bowls of M & M's and potato chips are placed on a table next to the Dora the Explorer sheet cake you ordered, a massive number “5” candle jetting out of its middle.

Remember when she was born. All conehead and piercing scream. How she spread across your chest and fell asleep. How you felt your dark heart open up for a split second, then close again.

Let the man next to you buy another round. Don't stop him when he puts his hand on your thigh. Don't stop him when he leans over and breathes into your neck, face buried in your hair. Remember when your husband used to do this. Remember when he stopped.

You met him at a coffee shop on Bleeker Street five days into your sobriety. Talked about books and shitty local poets and how no one writes anything worth a damn anymore. Six months later you married. You wore a black dress and wrote your own vows and watched as your aging parents held hands and cried, relieved you'd finally found someone who could put up with your shit.

Let the man kiss you now. Hard. Let it remind you of how wild you were back then. How all of that crazy has been replaced by a certain brand of peace others mistake for weakness. But addicts are never truly peaceful. Not down in the soul where it matters.

The jukebox spits out some music and everything in you moves, shifts. The mute button on your life suddenly lifted.

Go home.

Read more »

Ditch the 10,000 hour rule! Why Malcolm Gladwell’s famous advice falls short

Peter Brown, Henry Roediger III and Mark McDaniel in Salon:

Malcolm_gladwell2-620x412Here’s a study that may surprise you. A group of eight-year-olds practiced tossing beanbags into buckets in gym class. Half of the kids tossed into a bucket three feet away. The other half mixed it up by tossing into buckets two feet and four feet away. After twelve weeks of this they were all tested on tossing into a three-foot bucket. The kids who did the best by far were those who’d practiced on two- and four-foot buckets but never on three-foot buckets. Why is this? We will come back to the beanbags, but first a little insight into a widely held myth about how we learn.

Most of us believe that learning is better when you go at something with single-minded purpose: the practice-practice-practice that’s supposed to burn a skill into memory. Faith in focused, repetitive practice of one thing at a time until we’ve got it nailed is pervasive among classroom teachers, athletes, corporate trainers, and students. Researchers call this kind of practice “massed,” and our faith rests in large part on the simple fact that when we do it, we can see it making a difference. Nevertheless, despite what our eyes tell us, this faith is misplaced. If learning can be defined as picking up new knowledge or skills and being able to apply them later, then how quickly you pick something up is only part of the story. Is it still there when you need to use it out in the everyday world? While practicing is vital to learning and memory, studies have shown that practice is far more effective when it’s broken into separate periods of training that are spaced out. The rapid gains produced by massed practice are often evident, but the rapid forgetting that follows is not. Practice that’s spaced out, interleaved with other learning, and varied produces better mastery, longer retention, and more versatility.

More here.

A Portrait of Twenty-First Century Delhi

Jon Stock in The Telegraph:

Delhiweb_2836372bI’ll always remember the early hours of April 30, 1999. I was living in Delhi, working as a foreign correspondent for this newspaper, when the news broke that a beautiful model called Jessica Lal had been shot dead in a bar. The Tamarind Court in Mehrauli, where Jessica was serving drinks, was just up the road from our house and her violent death felt too close to home. It also shocked the nation, seeming to confirm that Delhi’s lawless elite was running amok. The bar had just shut when Manu Sharma, the son of a wealthy Indian MP, walked up to Jessica and asked for a drink. He offered her 1,000 rupees but she refused, telling him that he couldn’t even have one sip of alcohol. “I could have a sip of you for a thousand rupees,” Sharma replied. He then pulled out a gun, fired one shot into the ceiling and another into the model’s head.

Rana Dasgupta recalls her murder in his compelling, often terrifying, new book, Capital: a Portrait of Twenty-First Century Delhi. The author, whose debut novel, Solo (2010), won the Commonwealth Writers Prize, moved from Britain to Delhi in 2000, the year I left the city, and has lived there ever since. In Capital he sets out to show how Delhi has changed since the country’s decision in 1991 to embrace the principles of free enterprise and open markets. Mixing polemical chapters on the city’s history – the arrival of the Mughals, the decision by the British to move their capital from Calcutta to Delhi – with intimate interviews with billionaire businessmen, drug dealers, gurus and slum dwellers, Dasgupta argues that globalisation has had catastrophic consequences for a once great city.

More here.

The Gandhian Moment

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Karuna Mantena reviews Ramin Jahanbegloo’s “The Gandhian Moment” in the LA Review of Books:

Jahanbegloo’s wager is that Gandhian politics offer a path to overcoming authoritarian rule while avoiding the pitfalls of revolution. Whether Gandhian politics did stabilize India’s postcolonial transition is itself a controversial question; one need only think of the brutal partition that accompanied Indian independence. Nevertheless, Jahanbegloo is right to reconsider Gandhi from this angle — he was extremely sensitive to the dilemmas of transition. Indeed, one could argue that this was at the center of his continual meditations on the nature of swaraj (true independence or self-rule).

Directing Gandhi’s thinking toward contemporary concerns in this manner is a fruitful line of inquiry, and Jahanbegloo’s considerations are insightful. The strength of his insights, however, is sometimes diluted when they are applied too broadly. In what is essentially a pamphlet-length work, Jahanbegloo moves too quickly from recovering concepts such as shared sovereignty and citizen agency to extolling Gandhian goals of spiritualizing politics, promoting dialogic and intercultural criticism, reconciling individualism and mutuality, and promoting the more general Gandhian values of responsibility, tolerance, civility, and humility. True, many of these notions may be attributed to Gandhi himself, but it is hard to see their interconnection. In the end, their importance can only be declared rather than persuasively demonstrated.

Jahanbegloo’s attempt to recover the “ethical” thrust of Gandhian politics, however, merits careful consideration. As he observes, Gandhian politics has become a genuinely global phenomenon — a diffusion at once unexpected and inevitable. From the struggles against apartheid in South Africa in the 1980s to the velvet revolutions in Eastern Europe in the late 1980s, to the Arab Spring more recently, nonviolence has grown in popularity as an effective tool in antiauthoritarian campaigns. Moreover, in the literature on nonviolence, this revival has spawned theoretical analyses that view nonviolent collective action as essentially democratic. (See especially Jonathan Schell’s seminal work, The Unconquerable World.) Jahanbegloo’s worry is that nonviolence’s global reach, though significant, may be only partial, or fragile because partial — hence the need to integrate the politics of dissent within something more holistic.

Gandhi himself may have come up with this line of thought when, on the eve of independence, he complained that the Indian National Congress seemed only to have embraced nonviolence in a tactical way. Countless Gandhians have since lamented the adoption of nonviolence as a strategy separated from a deeper, more philosophical commitment to nonviolence.

More here.

Sunday Poem

Song 2

When I leave this little town
Harmonicas will play all night long..
But I won’t be here..
I know that as I sleep
The words I use and the way I walk are pantomimed..
In the square a horse drags a wooden cart full of bread: clack, clack..
A cold bench
Makes me take a good hard look
Forces my eyes open..
And I feel that something’s afoot
That something has just happened, maybe yesterday..
All that remains is a deep, far-off rumbling..
But before your heart rouses
To the sound,
You must fall asleep
Give into a deep fatigue..
The horse with the wooden cart
Stubbornly fights time:
Clack, clack — today's fresh bread, warm..
Once I, too, struggled with time..
But it would only grab me in its whirlwind
And spin me high up above the rooftops..
Now I know it’s small, contained
Unseen, like the bread in the cart’s wooden heart.
.

by Oleh Lysheha
from The Big Bridge
publisher: Molodist', Kyiv, 1989
Translation: by author
from A Hundred Years of Youth:
A Bilingual Anthology of 20th Century Ukrainian Poetry

Publisher: Litopys, Lviv, 2000

GABRIEL GARCIA MARQUEZ AND FIDEL CASTRO: A COMPLEX AND NUANCED COMRADERIE

Joel Whitney at Al Jazeera:

ScreenHunter_594 Apr. 20 09.44Gabriel Garcia Marquez’s 1967 novel “One Hundred Years of Solitude” is hailed as a masterpiece and harbinger of the literary genre, magical realism, a style of writing that influenced everyone from Isabel Allende to Salman Rushdie to Toni Morrison. With more than 30 million copies sold, the book is second only to Cervantes’s “Don Quixote” among Spanish-language novels. And Cervantes had, as one writer noted, a “four-century head start.”

But hours after the Nobel laureate died Thursday, the Cold War debate over his friendship with Cuba’s iconic revolutionary and former President Fidel Castro was rehashed as the singular stain on his otherwise glorious literary legacy.

While Castro’s revolution in its early days inspired admiration from the global left, his movement quickly became characterized by acts of repression and censorship. For the past four decades, Garcia Marquez had been criticized for maintaining his support even after Castro blessed the Soviet invasion of Czechoslovakia, with obituaries this week calling that support “scandalous” and a defense of “the indefensible.”

But the nuance of Garcia Marquez’s position was such that while he refused to break definitively with Castro, he never stopped criticizing Castro’s revolution, and even softened some of Castro’s roughest edges at a time when the Cuban leader was constantly under attack from the north.

More here.

Counterpuncher

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Perry Anderson on Alexander Cockburn, in New Left Review (image from Wikimedia Commons):

No other person I have ever known was so deeply and productively marked by family background. The relationship of sons to fathers is rarely without conflict; and where there is none, the effect is more typically disabling than empowering, or neutral. For a father to be object at once of adoration, emulation and emancipation would seem a contradiction in terms. Yet so it was in the case of Alexander. Throughout his life Claud was a model for him—he once said he thought of him every day—and his career would follow an arc often uncannily like that of Claud’s. Yet far from being a psychological shackle, reducing him to imitation, it was as if the intensity of the bond was the condition of an individuality out of the ordinary. The paradox, of course, says much about the parent who made it possible.

Claud Cockburn recounted his own life—up to the age of fifty-seven—in an artful and entertaining trilogy that records a remarkable career. Born in Peking in 1904, where his father was secretary to the British Legation during the Boxer Uprising, as a youth he spent much of his time, during breaks from education in England, in Budapest, while his father sorted out Allied war claims on Hungary. After Oxford, Claud first worked free-lance for the Times in Berlin, before becoming a correspondent for the paper in New York. Arriving in the US on the eve of the crash of 1929, he resigned his post in early 1932, returning first to Central Europe again, and then to England. There he created The Week, a confidential newsletter, exposing intrigues and scandals in high places, read and feared not only in the clubs and country houses of the British oligarchy, but their counterparts across the Continent. In 1934 he started writing for the Daily Worker, while contributing concurrently to Time and Fortune. After 1936 he reported on Spain for the Worker, and England for Pravda. During the War, he was diplomatic correspondent for the Worker, but in 1947 quit for a life in Ireland with his wife Patricia. There he wrote his three volumes of memoirs; five novels, one of which was made into a film by John Huston; contributed to Punch; and became an inspiration and collaborator of Private Eye. He died in 1981.

For the richness of this trajectory and the personality behind it, there is no substitute for Claud’s own reminiscences. But retrospectively, certain strands of particular moment for Alexander can be indicated.

More here.

Alive in the Sunshine: On Environmentalism and Basic Income

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Alyssa Battistoni in Jacobin (Illustration by Edward Carvalho-Monaghan):

[I]nternational disparities have, of course, long presented a challenge to those concerned with both domestic and global justice: how to acknowledge that America’s poor are wealthier than most of the world without simply concluding that they’re part of the problem? But while discussions of consumption tends to focus on a universal “we,” as epitomized by the famous Pogo Earth Day cartoon — “we have met the enemy, and he is us” — it’s important to look more closely within the rich world rather than simply heaping scorn on national averages.

Depictions of American consumerism tend to focus on the likes of Walmart and McDonald’s, suggesting that blame lies with the ravenous, grasping masses. Meanwhile it’s trendy for the wealthy to appear virtuous as they drive Priuses, live in homes that tout “green design,” and eat organic kale. But whether you “care about the environment,” believe in climate change, or agonize over your coffee’s origins doesn’t matter as much as your tax bracket and the consumption habits that go with it.

Consumption doesn’t correspond perfectly to income — in large part because of public programs like SNAP that supplement low-income households — but the two are closely linked. The US Congressional Budget Office estimates that the carbon footprint of the top quintile is over three times that of the bottom. Even in relatively egalitarian Canada, the top income decile has a mobility footprint nine times that of the lowest, a consumer goods footprint four times greater, and an overall ecological footprint two-and-a-half times larger. Air travel is frequently pegged as one of the most rapidly growing sources of carbon emissions, but it’s not simply because budget airlines have “democratized the skies” — rather, flying has truly exploded among the hyper-mobile affluent. Thus in Western Europe, the transportation footprint of the top income earners is 250 percent of that of the poor. And global carbon emissions are particularly uneven: the top five hundred million people by income, comprising about 8 percent of global population, are responsible for 50 percent of all emissions. It’s a truly global elite, with high emitters present in all countries of the world.

But that doesn’t mean America is off the hook altogether. The global wealthy may consume far more than the rest, but global consumption can’t be leveled out by bringing everyone up to even Western median levels; consumption in rich nations, even at relatively low levels of income, has to decline if we’re to achieve some measure of global equality.

For those in rich countries, this sounds suspiciously close to an argument for austerity: we’ve been profligate, and now the bill is coming due.

More here.

Thomas Piketty and Millennial Marxists on the Scourge of Inequality

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Timothy Shenk in The Nation (Photo: Emmanuelle Marchadour)):

Chest-pounding about methodology and decrees on capitalism would be of little interest if they were not joined to substantive intellectual discoveries. Piketty’s contributions on this front come in three interlocking clusters: historical, theoretical and political. Relying chiefly on data from Britain, the United States and France, he casts his gaze over what the French historian Fernand Braudel, cited by Piketty as one of his inspirations, termed the longue durée. Much of Capital in the Twenty-First Century is, essentially, a history of the modern world viewed through the relationship between two factors: economic growth, with all its promises, and the return on capital, a reward that goes to the small fraction of the population that has mastered what Tina Fey’s character in 30 Rockreferred to as “that thing that rich people do where they turn money into more money.”

The rich perfected that art a long time ago. According to Piketty, the average return on capital, after adjusting for inflation, has hovered around 5 percent throughout history, with a slight decline after World War II. Whatever problems capitalists will face in the future, he suggests, a crisis generated by falling profits is not likely to be among them. Economic growth, by contrast, has a far more abbreviated chronology. According to the most reliable estimates—sketchy, but better than nothing—for most of human history, economic growth was on the order of 0.1 percent a year, provided there were no famines, plagues or natural disasters. This gloomy record began to change for part of the world during the Industrial Revolution. Judged by later standards, “revolution” might seem too generous a phrase for growth rates in per capita output that ran to under 1.5 percent in both Western Europe and the United States; but compared with the entire earlier history of human existence, those rates were astonishing.

More impressive developments were in store. The twentieth century, Piketty writes, was the moment when “economic growth became a tangible, unmistakable reality for everyone.” In the United States, which had benefited earlier from high growth rates, per capita output ticked up to just under 2 percent between 1950 and 1970. In the same period, growth in Europe doubled that; Asian countries averaged just a step behind Europe; and many African nations reached numbers closer to—but ahead of—the United States.

Piketty is less concerned with this global story, however, than with a concurrent development in Europe. In the nineteenth century, growth had done nothing to reduce income inequality. This was the world Marx diagnosed in Capital, and in crucial respects, Piketty thinks he got it right. Not that the entire apparatus of Marxist political economy holds, if it ever did. On the key issue of the tendency for wealth to accumulate in fewer hands, though, Piketty believes Marx arrived at a profound insight.

More here.

THE SELECTED LETTERS OF ELIA KAZAN

9780307267160.dWendy Smith at The Washington Post:

In his blisteringly candid but skewed 1988 autobiography, “Elia Kazan: A Life,” he claimed that he had been miserable during the years of his greatest success, “straining to be a nice guy so people would like me.” He implied that the “mask” he wore “to hide a truer feeling” kept him from working honestly with his collaborators and destroyed his pleasure in that work. It’s impossible to believe this entirely as we read his detailed letters to Tennessee Williams, firmly laying out the structural problems he sees in “Camino Real” and “Cat on a Hot Tin Roof.” Kazan comes across as a strong, self-confident artist, unafraid to voice opinions he knows may upset his friend.

His commitment and integrity are even more evident in correspondence with studio executives over censorship troubles with the film versions of “Streetcar,” “East of Eden” and “Baby Doll.” A leading player in the battle to make American movies more adult, Kazan urged Jack Warner in 1955, “as a matter of self preservation, to put on the screen . . . only what they cannot and will not ever see on their TV . . . we must be bold.”

more here.