an interveiw with Doris Lessing at Paris Review:
I did take mescaline once. I’m glad I did, but I’ll never do it again. I did it under very bad auspices. The two people who got me the mescaline were much too responsible! They sat there the whole time, and that meant, for one thing, that I only discovered the “hostess” aspect of my personality, because what I was doing was presenting the damn experience to them the whole time! Partly in order to protect what I was really feeling. What should have happened was for them to let me alone. I suppose they were afraid I was going to jump out of a window. I am not the kind of person who would do such a thing! And then I wept most of the time. Which was of no importance, and they were terribly upset by this, which irritated me. So the whole thing could have been better. I wouldn’t do it again. Chiefly because I’ve known people who had such bad trips. I have a friend who took mescaline once. The whole experience was a nightmare that kept on being a nightmare—people’s heads came rolling off their shoulders for months. Awful! I don’t want that.
more here.