Tony Rothman in American Scientist:
Physics is the most fundamental of the natural sciences; it explains Nature at its deepest level; the edifice it strives to construct is all-encompassing, free of internal contradictions, conceptually compelling and—above all—beautiful. The range of phenomena physics has explained is more than impressive; it underlies the whole of modern civilization. Nevertheless, as a physicist travels along his (in this case) career, the hairline cracks in the edifice become more apparent, as does the dirt swept under the rug, the fudges and the wholesale swindles, with the disconcerting result that the totality occasionally appears more like Bruegel’s Tower of Babel as dreamt by a modern slumlord, a ramshackle structure of compartmentalized models soldered together into a skewed heap of explanations as the whole jury-rigged monstrosity tumbles skyward.
Of course many grand issues remain unresolved at the frontiers of physics: What is the origin of inertia? Are there extra dimensions? Can a Theory of Everything exist? But even at the undergraduate level, far back from the front lines, deep holes exist; yet the subject is presented as one of completeness while the holes—let us say abysses—are planked over in order to camouflage the danger. It seems to me that such an approach is both intellectually dishonest and fails to stimulate the habits of inquiry and skepticism that science is meant to engender.
More here.