An Old TB Vaccine Finds New Life in Coronavirus Trials

Anthony King in The Scientist:

One of the oldest vaccines could protect us against our newest infectious disease, COVID-19. The vaccine has been given to babies to protect them against tuberculosis for almost a century, but has been shown to shield them from other infections too, prompting scientists to investigate whether it can protect against the coronavirus. This Bacille Calmette-Guérin (BCG) vaccine, named after two French microbiologists, consists of a live weakened strain of Mycobacterium bovis, a cousin of M. tuberculosis, the bacterium that causes tuberculosis. BCG has been given to more than 4 billion individuals, making it the most widely administered vaccine globally. Because BCG protects babies against some viral infections in addition to TB, researchers decided to compare data from countries with and without mandatory BCG vaccination to see if immunization policies are linked to the number or severity of COVID-19 infections. A handful of preprint publications in the last two months noted that countries with an ongoing BCG vaccination program are experiencing lower death rates from COVID-19 than those without.

One study, for instance, found that mandatory BCG was associated with a significantly slower climb in both confirmed cases and deaths during the first 30-day period of an outbreak. Another modeled mortality in two dozen countries and reported that those without universal BCG vaccination, such as Italy, the US, and the Netherlands, were more severely affected by the pandemic than those with universal vaccination.

More here.



Friday Poem

Si Se Puede

When I take my morning walk now,
I am Pancho Villa. I am Che Guevara.

I am an outlaw in a mask and dark glasses.
I am starting a revolution.

Power to the peonies!
¡Vivas to the violets!

We would rather die on our knees,
sniffing at a flower,

than live, standing in line,
waiting for toilet paper to arrive.

Quivering, I throw my heart out,
six feet in every direction.

All that creeps, crawls, slithers,
or flies, I love.

I lower my mask.
I fling wide my arms.

I kiss death full on the mouth.

by Jose A, Alcantara
from Rattle Magazine
5/2/2020

______

Se se puede: If you can.

 

Thursday, May 7, 2020

A Dandy’s Guide to Decadent Self-Isolation

Samuel Rutter in The Paris Review:

I’m not ashamed to say that I bought Joris-Karl Huysmans’s Against Nature because of the cover: Frantisek Kupka’s The Yellow Scale (Self-Portrait) from 1907 is an exhilarating study of the color yellow. Its human subject, slouched in a wicker armchair, a cigarette dangling from one hand while a single, louche finger marks the page of a book, could be the perfect image of Des Esseintes, the dissolute antihero of Huysmans’s novel. Strictly speaking, the painting is a self-portrait of the habitually mustached Kupka, but it bears more than a passing resemblance to Charles Baudelaire, who haunts almost every page of Against Nature. This novel, about a dyspeptic aesthete who “took pleasure in a life of studious decrepitude,” spends some two hundred pages luxuriating in excess and opulence while the hero cuts himself off from the rest of society.

An old idea that persists about the novel is that it ought to be morally instructive in some way, that it should teach us the correct way to live. Certainly, when Against Nature was published in French in 1884, much of the resultant hand-wringing was because Huysmans’s hero learns nothing new from his misadventures in self-isolation. The problem, according to Émile Zola, was “that Des Esseintes is as mad at the start as he is at the end, that there is no form of progression.”

More here.

Physicists Criticize Stephen Wolfram’s ‘Theory of Everything’

Adam Becker in Scientific American:

Stephen Wolfram blames himself for not changing the face of physics sooner.

“I do fault myself for not having done this 20 years ago,” the physicist turned software entrepreneur says. “To be fair, I also fault some people in the physics community for trying to prevent it happening 20 years ago. They were successful.” Back in 2002, after years of labor, Wolfram self-published A New Kind of Science, a 1,200-page magnum opus detailing the general idea that nature runs on ultrasimple computational rules. The book was an instant best seller and received glowing reviews: the New York Times called it “a first-class intellectual thrill.” But Wolfram’s arguments found few converts among scientists. Their work carried on, and he went back to running his software company Wolfram Research. And that is where things remained—until last month, when, accompanied by breathless press coverage (and a 448-page preprint paper), Wolfram announced a possible “path to the fundamental theory of physics” based on his unconventional ideas. Once again, physicists are unconvinced—in no small part, they say, because existing theories do a better job than his model.

At its heart, Wolfram’s new approach is a computational picture of the cosmos—one where the fundamental rules that the universe obeys resemble lines of computer code.

More here.

Epidemic Empire: A Conversation with Anjuli Raza Kolb

Kali Handelman in The Revealer:

As the coronavirus began to take hold of our lives, our news, and became our undeniable, global, shared reality, I kept thinking about Anjuli Raza Kolb’s upcoming book, Epidemic Empire: Colonialism, Contagion, and Terror, 1817-2020. Raza Kolb’s book examines the metaphoric, literary, historical, and political relationships between terrorism and disease by tracing the trope of invasive, contagious violence from colonized India to post-9/11 America. Raza Kolb was generous enough to discuss her work with me in an extended conversation conducted primarily via email over the course of the last month.

More here.

Notes on Reading

Peter Orner at The Believer:

The book is Bernadette Mayer’s Midwinter Day. Mayer wrote it, the whole thing, every word, on December 22, 1978. Before today, I’d read only parts, but this is a book to be swallowed whole, hour by hour, the way Mayer wrote it. Therefore, I’m currently parked in a chair in the Lebanon, New Hampshire, public library, attempting a small degree of penance through reading.

Midwinter Day is a book that resists dumb hyperbole. And yet I’m going to go out on a flimsy limb and say, proclaim, ordain it to be the greatest celebration of family life ever written by an American—ever. Except, and here’s the thing, although Mayer’s husband, Lewis, and their two young daughters, Marie and Sophia, appear on every page—there’s breakfast, a trip to the library, lunch, dancing around the kitchen, reading out loud, squeezed-in sex, toys on the floor, dreaming—this book, at its core, is a dense 119-page record of Mayer’s fiercely individual consciousness across the seconds, minutes, hours of December 22, 1978.

more here.

Florian Schneider-Esleben of Kraftwerk

Amanda Petrusich at The New Yorker:

I can’t think of another song that better approximates the soft, giddy feeling of something new suddenly opening up. The song’s first few movements—the album version is almost twenty-three minutes, in total—make me feel as if I have just crested a long hill. Kraftwerk wrote often about motion—the band was interested in ideas of repetition, inertia, speed—which might be part of why its records feel so transporting. To anyone who feels a desire to briefly depart Earth, I say cue up “Autobahn,” close your eyes, and prepare to gently dissociate.

Kraftwerk would release six more albums between 1974 and 2003, including “Trans-Europe Express” and “The Man-Machine,” idiosyncratic masterpieces that continue to resonate broadly and deeply.

more here.

Thursday Poem

Instruction

Galaxies, galaxies everywhere
and nowhere a sign saying this way out
my parents told me don’t cry embarrassingly loudly
when you are once again by one or two men – in any case
stay away from liquid things
rather let your adult forms freeze
use the proper times for the pieces of your life
sleep when it’s night and never in the open air and make sure
you don’t eat more than seven but at least three times a day.
Don’t think of all the different body parts
that you could stick a pencil in and how deep
there are certain highways and nerve trails you’d better not –
you should find yourself an engineer, he’ll know practical stuff
the names of car parts and the elements, don’t suddenly
lay your head down on the table, don’t spill red wine
stay put hold on tight and let the ghost lights
be the ghost lights and finish your sentences.

by Gerda Blees
from:
 Dwaallichten
publisher: Uitgeverij Podium, Amsterdam

translation: Judith Wilkinson (original after “Read More”) Read more »

The Hundred Years’ War on Palestine – conquest and resistance

Matthew Hughes in The Guardian:

Rashid Khalidi’s account of Jewish settlers’ conquest of Palestine is informed and passionate. It pulls no punches in its critique of Jewish-Israeli policies (policies that have had wholehearted US support after 1967), but it also lays out the failings of the Palestinian leadership. Khalidi participated in this history as an activist scion of a leading Palestinian family: in Beirut during the 1982 Israeli invasion of Lebanon, and as part of the Palestinian negotiating team prior to the 1995 Israeli-Palestinian peace accords. He slams Israel but his is also an elegy for the Palestinians, for their dispossession, for their failure to resist conquest. It is a relentless story of Jewish-Israeli bad faith, alongside one of Palestinian corruption and political short-sightedness.

Khalidi sets out his stall early on: the Palestine-Israel war was never one between two national movements contesting equally over the same land but was always a “settler colonial conquest” by Europe-based Zionists whose founding father, Theodor Herzl, laid bare the project to Khalidi’s great-great-great uncle in 1899: Palestine’s indigenous population did not matter and would anyway benefit from the modernising effects of Jewish “pioneers”, such as America with its westward Manifest Destiny. For Khalidi, Jewish settlers, aided by Britain from 1917, and by the US later on, colonised Palestine, creating and securing Israel through six “wars”: the Balfour declaration of 1917; the 1947 UN partition plan; the 1967 UN security council resolution 242; the 1982 Israeli invasion of Lebanon; the 1993 Oslo peace accords; and Israeli leader Ariel Sharon’s Temple Mount visit in 2000.

Palestinian leaders from elite notables in the 1930s to Yasser Arafat and PLO-Fatah in the 60s to Hamas never successfully channelled the people’s passion to resist. This is not to “blame the victim”. Khalidi points to the huge obstacles in the way: in Britain and later the US, Protestant Christians bought into this “colonial war” to “civilise” the native population. There is a useful tension here between colonial superstructure and the patriarchal hierarchy and cronyism underpinning Palestinian elite leadership. Jewish-Israeli perfidy is central to Khalidi’s study but bubbling up through the text are key moments of resistance that demanded the insurgent organisation and charisma of a Michael Collins, a Mahatma Gandhi, or a Ho Chi Minh. This never happened. Instead, the well-organised Zionist movement (and Israel) instinctively divided disunited opposition.

More here.

How Science Trumps Denial

Mario Livio in Nautilus:

There’s an old belief that truth will always overcome error. Alas, history tells us something different. Without someone to fight for it, to put error on the defensive, truth may languish. It may even be lost, at least for some time. No one understood this better than the renowned Italian scientist Galileo Galilei. It is easy to imagine the man who for a while almost single-handedly founded the methods and practices of modern science as some sort of Renaissance ivory-tower intellectual, uninterested and unwilling to sully himself by getting down into the trenches in defense of science. But Galileo was not only a relentless advocate for what science could teach the rest of us. He was a master in outreach and a brilliant pioneer in the art of getting his message across. Today it may be hard to believe that science needs to be defended. But a political storm that denies the facts of science has swept across the land. This denialism ranges from the initial response to the COVID-19 pandemic to the reality of climate change. It’s heard in the preposterous arguments against vaccinating children and Darwin’s theory of evolution by means of natural selection. The scientists putting their careers, reputations, and even their health on the line to educate the public can take heart from Galileo, whose courageous resistance led the way.

A crucial first step, one that took Galileo a bit of time to take, was to switch from publishing his findings in Latin, as was the custom for scientific writings at the time, to the Italian vernacular, the speech of the common people. This enabled not just the highly educated elite but anyone who was intellectually curious to hear and learn about the new scientific work. Even when risking offense (which Galileo never shied away from)—for instance, in responding to a German Jesuit astronomer who disagreed with him on the nature of sunspots (mysterious dark areas observed on the surface of the sun)—Galileo replied in the vernacular, because, as he explained, “I must have everyone able to read it.” An additional motive may have been that Galileo wanted to ensure that no one would somehow distort the meaning of what he had written.

Galileo also understood that while the Church had the pomp and magic of decades of art and music, science had the enchantment of a new invention—the telescope.

More here.

Wednesday, May 6, 2020

Edward Said’s life and afterlives

Rashid Khalidi in The Nation:

Seventeen years after his death, Edward Said remains a powerful intellectual presence in academic and public discourse, a fact attested to by the appearance of two important new books. After Said, edited by Bashir Abu-Manneh, offers assessments of Said’s vast body of scholarship by a dozen noted writers and academics. The Selected Works of Edward Said, 1966–2006, edited by Moustafa Bayoumi and Andrew Rubin, two former students, is an expanded version of The Edward Said Reader, which was published a few years before his death in 2003. The Reader offered us a full picture of Said’s breadth and influence as a public intellectual; the new collection is more than 150 pages longer and includes eight essays that didn’t appear in the earlier volume, plus a new preface and an expanded introduction. The newly included essays range from overtly political sallies to reflective meditations on the “late style” in music and literature that were published posthumously. Some of them, like “Freud and the Non-European,” reflect concerns that preoccupied him toward the end of his life and are among the most complex and subtle of his writings. Others remind us how widely read he was, how broad his interests were, and how penetrating his insights could be. Coupled with the reflections on his major works in After Said, they also give the reader a sense of the consistency of his politics, imbued with a universalist and cosmopolitan humanism that sat at the center of his literary and political writings.

It is not surprising that so many people are still reading and grappling with Said’s ideas.

More here.

Poultry Farming, COVID-19, and the Next Pandemic

Matt Johnson in Quillette:

Upton Sinclair published The Jungle in 1906 to expose the horrific conditions in American factories at the turn of the century. While he intended to highlight the misery and abuse of the workers, his graphic descriptions of disgusting and unsanitary conditions at slaughterhouses were what most outraged the public. President Theodore Roosevelt was among the indignant readers, and he used the outcry over The Jungle to push for passage of the 1906 Food and Drugs Act and the Federal Meat Inspection Act. “I aimed for the public’s heart,” Sinclair later wrote, “and by accident hit it in the stomach.” Jonathan Safran Foer’s Eating Animals (published in 2009)—and the chapter “Influence/Speechlessness,” in particular, about the US poultry industry and the risks it poses to our health—ambitiously aims for the reader’s heart and stomach at the same time.

Foer gives us a glimpse into the hellish life of the more than nine billion factory farmed chickens “produced”—all 56.8 billion pounds of them, as the National Chicken Council (NCC) proudly announces—by the industry every year. “It’s hard to get one’s head around the magnitude of 33,000 birds in one room,” Foer writes, something he witnessed firsthand when he broke into a poultry farm with an unnamed animal rights activist.

More here.

Heiner Müller—poet, playwright, and informant—embodied the divisions of postwar Germany

Holly Case at the Poetry Foundation:

“Unlike Lenin, Hitler came to power in a free election, which makes Auschwitz also the result of free elections.” The East German dramatist and poet Heiner Müller wrote these words in late November of 1989, on the eve of the first free elections on the territory of the German Democratic Republic (socialist East Germany) since 1932, when the Nazis came to power. Never one for feel-good moments, Müller’s thinking was deeply out of sync with the general euphoria that followed the fall of the Berlin Wall. While giving a speech on Berlin’s Alexanderplatz on November 4, 1989, he didn’t echo the sweeping optimism of the other speakers but read a statement calling for independent unions; many in the crowd booed him. In his autobiography, Müller admitted that the fall of the GDR had not been easy for him: “Suddenly there was no adversary…whoever no longer has an enemy will meet him in the mirror.”

That line proved prophetic. As he was dying of throat cancer in 1995, just a few years after assuming the directorship of Bertolt Brecht’s famous Berliner Ensemble theater, he expressed admiration for his fatal tumor.

More here.

Hermeneutics and the Framing of “Truth”

William Egginton at the LARB:

This point goes to the heart of Zabala’s book, as well as to the mistaken concerns about the hermeneutic tradition he defends. To say, with Zabala, that “there is no ‘neutral observation language’ that can erase human differences,” and that “these differences are not the source of our problems but rather the only possible route to their provisional solution,” is not to embrace or give succor to those making power grabs using bald assertions of “alternative facts,” but the very opposite. It is to say that “facts, information, and data by themselves do nothing. ‘Facts remain robust,’ as [philosopher of science Bruno] Latour says, ‘only when they are supported by a common culture, by institutions that can be trusted, by a more or less decent public life, by more or less reliable media.’” Let’s be quick to douse the realist canard that is sure to arise at this point — that relativist arguments are self-negating since, if all statements of fact are subject to cultural, historical, and institutional contexts, then so is this one — by stating the obvious: of course Zabala’s (and my) positions are subject to the same frame-dependency as anyone else’s, but this is no more self-refuting or paradoxical than to say that all truth statements are made in a natural language that not everyone understands, including this one.

more here.

The Psyche of Snow White

Lucy Lethbridge at Literary Review:

In its different versions, the tale has several recurring elements, though not all of them are present in every case. The chief one is the jealousy that rages in a beautiful mother (or stepmother, or mother-in-law) for her even more beautiful daughter. Then there is the mirror (or sometimes the sun or the moon and, in one version, a trout in a deep well) that reflects back to the mother the truth about her own beauty being surpassed. Someone is sent to kill the girl in the forest, sometimes a huntsman but occasionally an old woman or a witch; beguiled by the child’s beauty, they set her free, returning to the mother with a bloodstained shirt or an animal’s entrails. Lost in the forest, the child often comes upon a house in which to shelter. It might be lived in by untidy dwarfs (this gave Disney an opportunity to make Snow White into a perfect 1930s housewife), but often its inhabitants are immaculately tidy dwarfs (as in the Grimms’ version), and occasionally they are gangs of robbers or even brothers who look upon Snow White as a sister to be protected. Sometimes there are seven of them in the house, sometimes twelve.

more here.

Wednesday Poem

Against Roses

A long eugenic past
reduces roses to
a vain and pampered caste.

Their charm is artifice,
their fragile shell of cells
unfit for wilderness.

Their languid symmetries
and anorexic airs
exalt deformities.

A run of blossoms, thick
and tangled by the road,
displays a truer pick.

Prefer the bindweed vines
that cannot stand alone
yet clench the mossy spines

of trees and grasp as tight
as nightmares or disease
while hoarding hints of light.

By cloning a delight,
obsessing towards some form,
we dull what should excite.

A rose bouquet contrives
to label wordless joy
when nothing true survives.

A.M. Juster