CAR T-cell therapy takes woman from bedridden to ‘perfectly fine’

Michael Le Page at New Scientist:

A woman who had three different autoimmune conditions has not required treatments for almost a year after her immune cells were genetically modified and used to kill off the rogue cells attacking her body. “She was deathly sick and bedridden at the time we met her, and we treated her, and seven days later, she got out of bed,” says Fabian Müller at the University Hospital of Erlangen in Germany. Within months she appeared to be fully recovered. “I just saw her yesterday. She’s perfectly fine,” says Müller, speaking 11 months after the treatment.

This woman is one of a growing number of people with autoimmune conditions who have been successfully treated this way, and the first to have three different ones treated simultaneously. “The really crazy thing is that you have three autoimmune diseases, and all three of them, by chance, you can tackle with one treatment,” says Müller.

More here.

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