Alzheimer’s Disease Affects Tissues Beyond the Brain

Shelby Bradford in The Scientist:

Alzheimer’s disease is characterized by the accumulation of amyloid β (Aβ) peptides and the protein Tau in neurons in the brain. As a result, researchers focused on the central nervous system to study this disorder and its possible treatments. However, recent studies point to correlations between Alzheimer’s disease and alterations in peripheral organ systems, including the gut microbiome.1,2 Still, researchers do not completely understand if these peripheral disruptions are caused by the neurodegeneration or if they augment the existing disease symptoms.

More here.

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