What Makes the Stanford Rape Case So Unusual

Adrienne Lafrance in The Atlantic:

It’s impossible to know how many sexual assaults go unreported. But the 23-year-old victim in a sexual assault case that has touched off a national uproar did speak out. “You don’t know me, but you’ve been inside me, and that’s why we’re here today,” she said in a statement, which she read to her attacker in a Palo Alto courtroom last week. The woman went on to describe, in painstaking detail, what she experienced in the hours and months after she was found half-naked and unconscious behind a dumpster on Stanford’s campus the night of the attack. The victim’s statement to Brock Turner, the former Stanford student convicted of sexually assaulting her, has been viewed online millions of times since last week. A CNN anchor read the statement, in full, on television. Representative Jackie Speier, a California Democrat, read it aloud on the House floor. The case, which resulted in a six-month jail sentence and probation for Turner, has touched off furor among those who say the punishment is too light, and sparked vigorous debate about the intersection of sexual assault, privilege, and justice.

This is an astounding moment, in part because it’s so rare for sexual violence, despite its ubiquity, to garner this kind of attention. “It’s incredible,” said Michele Dauber, a Stanford Law School professor who has pressed for the recall of the judge who sentenced Turner. “Why did that happen? First of all, it’s the tremendous power and clarity of thought that is reflected in the survivor’s statement.” “She is helping people to understand this experience in a visceral and clear way,” Dauber added. “And she’s brushing away all the really toxic politics around campus assault that have built up. People have said, ‘How can we really believe these women? It’s his word against hers.’ This men’s rights movement has emerged. And there’s been a lot of rage happening out there. Then, whoosh, [this statement] really reframed it.”

More here.

Triggering the protein that programs cancer cells to kill themselves

From KurzweilAI:

Programmed cell death (a.k.a. apoptosis) is a natural process that removes unwanted cells from the body. Failure of apoptosis can allow cancer cells to grow unchecked or immune cells to inappropriately attack the body. The protein known as Bak is central to apoptosis. In healthy cells, Bak sits in an inert state but when a cell receives a signal to die, Bak transforms into a killer protein that destroys the cell.Institute researchers Sweta Iyer, PhD, Ruth Kluck, PhD, and colleagues unexpectedly discovered that an antibody they had produced to study Bak actually bound to the Bak protein and triggered its activation. They hope to use this discovery to develop drugs that promote cell death.

The researchers used information about Bak’s three-dimensional structure to find out precisely how the antibody activated Bak. “It is well known that Bak can be activated by a class of proteins called ‘BH3-only proteins’ that bind to a groove on Bak. We were surprised to find that despite our antibody binding to a completely different site on Bak, it could still trigger activation,” Kluck said. “The advantage of our antibody is that it can’t be ‘mopped up’ and neutralized by pro-survival proteins in the cell, potentially reducing the chance of drug resistance occurring.”

More here.