Cialis is an erectile dysfunction drug. Could it also help you live longer?

Will Stone at NPR:

Tadalafil [brand name: Cialis] belongs to the same class of drugs as sildenafil, i.e., Viagra – with the primary difference being that its effect lasts considerably longer.

While both have been on the market for decades, a handful of large studies, many of them published in recent years, have shown that men taking the drug fare better: They have lower rates of cardiovascular disease and death, and, in some cases, are less likely to develop dementia.

The major studies in this area are observational – and retrospective – meaning they can only show associations, not that tadalafil was the definitive cause.

But the findings are remarkably “consistent” across the literature, says Kloner, whose lab has studied these medications extensively. “It’s a very interesting signal.”

The research has surfaced in the online longevity conversation, and prominent voices – from Stanford neuroscientist and podcaster Andrew Huberman to the immortality-seeking tech mogul Bryan Johnson – have talked up the idea of taking tadalafil for more than sex.

More here.

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