Heidi Ledford & Max Kozlov in Nature:
Researchers have made eggs from the cells of male mice — and showed that, once fertilized and implanted into female mice, the eggs can develop into seemingly healthy, fertile offspring.
The approach, announced on 8 March at the Third International Summit on Human Genome Editing in London, has not yet been published and is a long way from being used in humans. But it is an early proof-of-concept for a technique that raises the possibility of a way to treat some causes of infertility — or even allow for single-parent embryos. “This is a significant advance with significant potential applications,” says Keith Latham, a developmental biologist at Michigan State University in East Lansing.