Jeffrey S. Flier in Quillette:
There has been consensus in the scientific community that, notwithstanding the partial effectiveness of lockdowns, other non-pharmacologic interventions, and potential therapeutics, the development and production of a safe and effective vaccine would eventually be necessary to fully control this pandemic. But it is important to remember that some viruses resist vaccine treatment (as so far has been the case with HIV). In other cases, vaccines are developed, but only after many years of research, testing, and regulatory protocols. Attempts to produce vaccines for the two other known human coronavirus diseases—SARS, which was identified in 2002, and MERS, in 2012—were unsuccessful. So optimism has been appropriately muted in the case of COVID-19. And it’s in this context that these preliminary results are so remarkable.