The Earth has 50 billion tons of DNA. What happens when we have the entire biocode?

Dawn Field in Aeon:

In case you weren’t paying attention, a lot has been happening in the science of genomics over the past few years. It is, for example, now possible to read one human genome and correct all known errors. Perhaps this sounds terrifying, but genomic science has a track-record in making science fiction reality. ‘Everything that’s alive we want to rewrite,’ boasted Austen Heinz, the CEO of Cambrian Genomics, last year.

It was only in 2010 that Craig Venter’s team in Maryland led us into the era of synthetic genomics when they created Synthia, the first living organism to have a computer for a mother. A simple bacterium, she has a genome just over half a million letters of DNA long, but the potential for scaling up is vast; synthetic yeast and worm projects are underway.

Two years after the ‘birth’ of Synthia, sequencing was so powerful that it was used to extract the genome of a newly discovered, 80,000-year-old human species, the Denisovans, from a pinky bone found in a frozen cave in Siberia. In 2015, the United Kingdom became the first country to legalise the creation of ‘three-parent babies’ – that is, babies with a biological mother, father and a second woman who donates a healthy mitochondrial genome, the energy producer found in all human cells.

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