Gene-editing method tackles HIV in first clinical test

Sarah Reardon in Nature:

HivA clinical trial has shown that a gene-editing technique can be safe and effective in humans. For the first time, researchers used enzymes called zinc-finger nucleases (ZFNs) to target and destroy a gene in the immune cells of 12 people with HIV, increasing their resistance to the virus to the virus. The findings are published today in The New England Journal of Medicine1. “This is the first major advance in HIV gene therapy since it was demonstrated that the ‘Berlin patient’ Timothy Brown was free of HIV,” says John Rossi, a molecular biologist at the Beckman Research Institute of the City of Hope National Medical Center in Duarte, California. In 2008, researchers reported that Brown gained the ability to control his HIV infection after they treated him with donor bone-marrow stem cells that carried a mutation in a gene called CCR5. Most HIV strains use a protein encoded by CCR5 as a gateway into the T cells of a host’s immune system. People who carry a mutated version of the gene, including Brown's donor, are resistant to HIV.

But similar treatment is not feasible for most people with HIV: it is invasive, and the body is likely to attack the donor cells. So a team led by Carl June and Pablo Tebas, immunologists at the University of Pennsylvania in Philadelphia, sought to create the beneficial CCR5 mutation in a person’s own cells, using targeted gene editing. The researchers drew blood from 12 people with HIV who had been taking antiretroviral drugs to keep the virus in check. After culturing blood cells from each participant, the team used a commercially available ZFN to target the CCR5 gene in those cells. The treatment succeeded in disrupting the gene in about 25% of each participant’s cultured cells; the researchers then transfused all of the cultured cells into the participants. After treatment, all had elevated levels of T cells in their blood, suggesting that the virus was less capable of destroying them. Six of the 12 participants then stopped their antiretroviral drug therapy, while the team monitored their levels of virus and T cells. Their HIV levels rebounded more slowly than normal, and their T-cell levels remained high for weeks. In short, the presence of HIV seemed to drive the modified immune cells, which lacked a functional CCR5 gene, to proliferate in the body. Researchers suspect that the virus was unable to infect and destroy the altered cells. “They used HIV to help in its own demise,” says Paula Cannon, who studies gene therapy at the University of Southern California in Los Angeles. “They throw the cells back at it and say, ‘Ha, now what?’”

More here.

Arundhati Roy, the Not-So-Reluctant Renegade

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Siddhartha Deb in the NYT Magazine:

“I’ve always been slightly short with people who say, ‘You haven’t written anything again,’ as if all the nonfiction I’ve written is not writing,” Arundhati Roy said.

It was July, and we were sitting in Roy’s living room, the windows closed against the heat of the Delhi summer. Delhi might be roiled over a slowing economy, rising crimes against women and the coming elections, but in Jor Bagh, an upscale residential area across from the 16th-century tombs of the Lodi Gardens, things were quiet. Roy’s dog, Filthy, a stray, slept on the floor, her belly rising and falling rhythmically. The melancholy cry of a bird pierced the air. “That’s a hornbill,” Roy said, looking reflective.

Roy, perhaps best known for “The God of Small Things,” her novel about relationships that cross lines of caste, class and religion, one of which leads to murder while another culminates in incest, had only recently turned again to fiction. It was another novel, but she was keeping the subject secret for now. She was still trying to shake herself free of her nearly two-decade-long role as an activist and public intellectual and spoke, with some reluctance, of one “last commitment.” It was more daring than her attacks on India’s occupation of Kashmir, the American wars in Iraq and Afghanistan or crony capitalism. This time, she had taken on Mahatma Gandhi.

More here.

Imaginary Jews

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Michael Walzer reviews David Nirenberg's Anti-Judaism: The Western Tradition, in the NYRB:

What Nirenberg has written is an intellectual history of Western civilization, seen from a peculiar but frighteningly revealing perspective. It is focused on the role of anti-Judaism as a constitutive idea and an explanatory force in Christian and post-Christian thought—though it starts with Egyptian arguments against the Jews and includes a discussion of early Islam, whose writers echo, and apparently learned from, Christian polemics. Nirenberg comments intermittently about the effects of anti-Judaism on the life chances of actual Jews, but dealing with those effects in any sufficient way would require another, and a very different, book.

Anti-Judaism is an extraordinary scholarly achievement. Nirenberg tells us that he has left a lot out (I will come at the end to a few things that are missing), but he seems to know everything. He deals only with literature that he can read in the original language, but this isn’t much of a limitation. Fortunately, the chapter on Egypt doesn’t require knowledge of hieroglyphics; Greek, Hebrew, and Latin are enough. Perhaps it makes things easier that the arguments in all the different languages are remarkably similar and endlessly reiterated.

A certain view of Judaism—mainly negative—gets established early on, chiefly in Christian polemics, and then becomes a common tool in many different intellectual efforts to understand the world and to denounce opposing understandings. Marx may have thought himself insightful and his announcement original: the “worldly God” of the Jews was “money”! But the identification of Judaism with materialism, with the things of this world, predates the appearance of capitalism in Europe by at least 1,500 years.

More here.

The ‘Failure’ of the ‘Reset:’ Obama’s Great Mistake? Or Putin’s?

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Daniel Nexon in the Washington Post:

Russia’s political organization is fundamentally imperial in character, composed of a hodgepodge of political units that range from the fully integrated to the semi-sovereign and autonomous. As my colleague, Charles King, wrote in 2003:

“Central power, where it exists, is exercised through subalterns who function as effective tax- and ballot-farmers; they surrender up a portion of local revenue and deliver the votes for the center’s designated candidates in national elections in exchange for the center’s letting them keep their own fiefdoms.”

Nowhere is this kind of arrangement more vividly illustrated than in Chechnya, where Moscow ‘solved’ its separatist problem by devolving power to a local viceroy, Akhmed Kadyrov and, after his assassination, his son, Ramzan Kadyrov.

Second, Moscow’s strategy for managing its internal relations — relying on subalterns, exploiting ethnic divisions, deploying military forces and using the toolkit of electoral authoritarianism — extends, if often in attenuated form, to those states it considers as falling within its “privileged sphere of influence.” It has long backed and leveraged secessionist movements in, among other places, Moldova, Georgia and Azerbaijan in the pursuit of political control. Although not always successful, this pattern dates back to the Soviet era and, before that, the Russian Empire. Indeed, the Kremlin’s power-political practices are as perennial as they are limited. In a theoretically sophisticated Security Studies article, Iver B. Neumann and Vincent Pouliot show that Moscow’s quest for great-power status and recognition, combined with its inability to achieve “insider status” in the international order, invariably drives it back to the same repertoire of asserting great-power perquisites in ways that shock and alarm the international community. Did German Chancellor Angela Merkel describe Putin as living in “another world” after her March 2 phone conversation with him? If not, then sometimes truth does indeed reside in fiction.

More here. For more on the Ukraine, also see Anatol Lieven, and Alexander Motyl.

Trigger Happy

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Jenny Jarvie in The New Republic:

[T]he headline above would, if some readers had their way, include a “trigger warning”—a disclaimer to alert you that this article contains potentially traumatic subject matter. Such warnings, which are most commonly applied to discussions about rape, sexual abuse, and mental illness, have appeared on message boards since the early days of the Web. Some consider them an irksome tic of the blogosphere’s most hypersensitive fringes, and yet they've spread from feminist forums and social media to sites as large as the The Huffington Post. Now, the trigger warning is gaining momentum beyond the Internet—at some of the nation's most prestigious universities.

Last week, student leaders at the University of California, Santa Barbara, passed a resolution urging officials to institute mandatory trigger warnings on class syllabi. Professors who present “content that may trigger the onset of symptoms of Post-Traumatic Stress Disorder” would be required to issue advance alerts and allow students to skip those classes. According to UCSB newspaper The Daily Nexus, Bailey Loverin, the student who sponsored the proposal, decided to push the issue after attending a class in which she “felt forced” to sit through a film that featured an “insinuation” of sexual assault and a graphic depiction of rape. A victim of sexual abuse, she did not want to remain in the room, but she feared she would only draw attention to herself by walking out.

On college campuses across the country, a growing number of students are demanding trigger warnings on class content. Many instructors are obliging with alerts in handouts and before presentations, even emailing notes of caution ahead of class. At Scripps College, lecturers give warnings before presenting a core curriculum class, the “Histories of the Present: Violence,” although some have questioned the value of such alerts when students are still required to attend class. Oberlin College has published an official document on triggers,advising faculty members to “be aware of racism, classism, sexism, heterosexism, cissexism, ableism, and other issues of privilege and oppression,” to remove triggering material when it doesn't “directly” contribute to learning goals and “strongly consider” developing a policy to make “triggering material” optional. Chinua Achebe's Things Fall Apart, it states, is a novel that may “trigger readers who have experienced racism, colonialism, religious persecution, violence, suicide and more.”

More here.

Derrida and the Death Penalty

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Jan Mieszkowski reviews Jacques Derrida's The Death Penalty, Volume I in the LA Review of Books:

[T]he driving concern of the seminar is as clear as it is provocative. “Never to my knowledge,” Derrida declared in a contemporaneous conversation with French historian Élisabeth Roudinesco, “has any philosopher as a philosopher, in his or her own strictly and systematically philosophical discourse, never has any philosophy as suchcontested the legitimacy of the death penalty.” As an experiment, I shared this claim with a number of academic philosophers. Their initial skepticism quickly turned to surprise as they realized that, as Derrida observes, virtually all of the major philosophers were either ardent advocates of capital punishment, reluctant apologists for it, or markedly silent on the topic. Even those, Derrida adds, “who maintained a public discourse against the death penalty never did so, to my knowledge — and this is my provisional hypothesis — in a strictly philosophical way.”

One may raise an eyebrow at the formulation “in a strictly philosophical way,” if only because one can’t help imagining how Derrida himself, in another mood, might have pounced on it: can philosophy ever be strictlyphilosophical? Doesn’t philosophy come into its own precisely by losing itself when it seeks a way of its own? Yet these are precisely Derrida’s concerns, for at issue is not just what certain philosophers have said about the death penalty, but whether Western philosophy is in some way organized by its investment in this particular doctrine of punishment. Derrida’s suggestion is that the death penalty is both one penalty among others and the penalty of penalties, a transcendental condition of possibility of justice and punishment. Criminal law as we know it, if not law in general, would be inconceivable in its absence. The death penalty, he writes, “has always been the effect of an alliance between a religious message and the sovereignty of the state,” state sovereignty, first and foremost, being the power over the life and death of subjects. It is therefore not simply a question of maintaining that we can only understand the death penalty by explaining the relations between traditional theological, juridical, and political discourses. The reigning theological-juridico-political constellation can be approached and understood only through a study of capital punishment.

More here.

Christopher Lasch and the Role of the Social Critic

LaschMichael J. Kramer at The Point:

The Culture of Narcissism solidified Lasch’s reputation as a leading anti-modernist critic of an America that seemed to have lost its balance as it rollerskated into oblivion. Mistrusting America’s affluence and growing technological achievements, Lasch even critiqued the anti-authoritarian liberation struggles of the 1960s, which belonged for him to the same modernist cult of progress that, failing to recognize necessary limits, would destroy all in its path. The counterculture’s myth of exaggerated self-realization was but the flipside of the retreat into basic self-preservation. Detached by state and market from connections to a more sustaining sense of purpose or obligation, Americans inhabited a culture that left them rootless.

But Lasch should not be remembered merely as a grumbling reactionary. What he feared was “liberation,” not “modernity”—dismissing anti-modernist nostalgia as the fantasy of progress in reverse. For most of his life (he died of cancer in 1994), he remained committed to a more egalitarian society and clung to the hope that change might still occur. As he said toward the end of a career that had turned, beginning with Narcissism, increasingly dark and pessimistic: he still had faith even though he lacked optimism. It was a statement that flummoxed many interviewers, but it is key to understanding Lasch’s complex vision of American culture—and of the role of the social critic within it.

more here.

On Tolstoy and Mortality

322x500xrb_giraldi_01_opt_86.jpg,qitok=rZu8_eN5.pagespeed.ic.xvjGbighvzWiliam Giraldi at The Virginia Quarterly Review:

Written in 1886, The Death of Ivan Ilyich was the first fiction Tolstoy published after the spiritual upheaval he chronicles in Confession. It’s easy to imagine Ilyich as the old and bearded sage-​looking man Tolstoy was upon his death, but he’s only forty-​five years old, and this fact adds to the tremendous pathos of the story: The death of a young man is always more awful than the death of an old man. The priest gives Ilyich little spiritual consolation, and the doctors are self-​important fools, incapable of mitigating his pain. His co-​workers are disgusted by the thought of his wasting body and care only about jockeying for cozier positions once he dies. His wife and children, occupied by the minutiae of their quotidian lives, refuse to admit what has befallen him. He finds their refusal to confront this fanged truth most disgusting of all: “Ivan Ilyich’s chief torment was the lie—​that lie, for some reason recognized by everyone, that he was only ill but not dying.” His sole comfort comes from Gerasim, the peasant servant who does not recoil from the foul stench, who accepts the inevitability of all flesh. If Ilyich’s upper-​crust friends regard death as indecent, Gerasim knows otherwise: His peasant’s dirty-​hands understanding of life, his calm acceptance of every person’s fate, helps to calm Ilyich into his own acceptance. (The peasantry’s calm acceptance of death, by the way, can be noticed in Turgenev, Dostoevsky, and Solzhenitsyn, to name a few—​it seems to fall somewhere in line between Russian literary trope and Russian cultural myth.) Relief for Ilyich comes only after he has followed Gerasim’s lead and acquiesced to his fate.

more here.

A stacked deck at the New York Times

Pareene_pilon_b24.5_630Alex Pareene at The Baffler:

One great problem with financial journalism, especially in the decades leading up to the crash, has been that it’s often written in an argot understandable only to the already highly financially literate. Sorkin doesn’t usually employ such specialized language. This has led to the mistaken belief that he’s explaining the industry to regular people. In fact, he is a dutiful Wall Street court reporter, telling important people what other important people are thinking and saying. At the same time, he is Wall Street’s most valuable flack. He isn’t explainingfinance to the people—you’d be better served reading John Kenneth Galbraith to understand how finance works—he’s justifying it.

The modern finance industry is at a loss when it comes to justifying its own existence. Its finest minds can’t explain why we wouldn’t be better off with a much simpler and more heavily circumscribed model of capital formation. Sorkin likewise can’t make his readers fully grasp why the current system—which turns large amounts of other people’s money and even more people’s debt into huge paper fortunes for a small super-elite, and in such a way as to regularly imperil the entire worldwide economic order—is beneficial or necessary. But the New York Times and Wall Street each need him to try.

more here.

Iranian Women Push To Tighten Gender Gap

Deborah Amos in NPR:

IranIran is starting to see a re-launch of activist groups following the election last year of President Hassan Rouhani. Social movements were scarce after the government crushed public protests known as the Green Movement following the 2009 elections. After the decisive vote for Rouhani, a surge of hope in Iran has attracted activists back to the political arena. Iranian women, in particular, are seizing the opportunity. On a recent afternoon in north Tehran two professional women huddle with an adviser to the Ministry of Mines and Trade. They are building a strategy for promoting jobs for women in government and the private sector.

This would have been impossible under the previous president, Mahmoud Ahmadinejad, explains Sohaila Jelodorzadeh, a former member of parliament, now a professor of textile engineering. “We were ignored,” she says, adding, “No, it was more than ignored. We faced social and political problems.” Now, she is politically active again, working with Soraya Maknoon, a former university chancellor, to champion women's employment. Women make up more than 60 percent of the college population in Iran but are less than 20 percent of the working population. “We want to make better use of their knowledge. This is important, not just to have degrees,” says Maknoon. It is just one example of a trend in Iran, says Kevan Harris, an Iran specialist from Princeton University. “Urban issues, pollution issues, environmental issues, women's issues,” Iranians are forming groups to tackle the major problems facing the country, he says. “The universities now are back, full of student politics, so we are going through a wave of mobilization from below in Iran.” The gender gap in employment may be one of the toughest challenges despite a huge social shift on college campuses. After the 1979 revolution, Iran's Islamic government convinced even the most traditional families that it was safe to send their daughters away to college.

More here.

Wednesday Poem

On a Day With a Gentle Breeze

*
You arrived on a day with a gentle breeze
crying suddenly as if you came rolling out of the heavens
All of a sudden, at that moment, inside me
rose up the roar of a lioness,
“I will endure anything for you!”

*
A baby recalls its heavenly friends
though its eyes do not see well yet
It smiles gently in the morning light
the way an empty swing
sways slightly in the breeze

*
It looks like the start of a hot day.
Golden dewdrops have formed on the bamboo leaves outside my window.
I am recovering day by day.
Looking forward to happy days when I can work
I rest for now, a clear pool of time

*
You come to me and suckle
like a little fish
picking at a lotus leaf

*
You cast a green shade
over my solitary life
like a readily swaying maple branch
arching outside my window –
just a shapeless flickering light
yet you bring me thoughts of infinity
With a few beautiful words
and a soft loving gaze
you glue my solitary life
to this world
.

by Nao Inoue
from Ooinaru Jyumoku
publisher: Sakurai Shoten, Tokyo, 1947
translation: Takako lento, 2009

Original Japanese

How memory and thought alter the meaning of odors

From KurzweilAI:

GranuleOdors have a way of connecting us with moments buried deep in our past. But researchers have long wondered how the process works in reverse: how do our memories shape the way sensory information is collected? In work published in Nature Neuroscience,scientists from Cold Spring Harbor Laboratory (CSHL) demonstrate for the first time a way to observe this process in awake animals. The team, led by Assistant Professor Stephen Shea, was able to measure the activity of a group of inhibitory neurons that links the odor-sensing area of the brain with brain areas responsible for thought and cognition. This connection provides feedback so that memories and experiences can alter the way smells are interpreted. The inhibitory neurons that forge the link are known as granule cells. They are found in the core of the olfactory bulb, the area of the mouse brain responsible for receiving odor information from the nose. Granule cells in the olfactory bulb receive inputs from areas deep within the brain involved in memory formation and cognition. Granule cells relay the information they receive from neurons involved in memory and cognition back to the olfactory bulb. There, the granule cells inhibit the neurons that receive sensory inputs. In this way, “the granule cells provide a way for the brain to ‘talk’ to the sensory information as it comes in,” explains Shea. “You can think of these cells as conduits which allow experiences to shape incoming data.”

Why might an animal want to inhibit or block out specific parts of a stimulus, like an odor? Every scent is made up of hundreds of different chemicals, and “granule cells might help animals to emphasize the important components of complex mixtures,” says Shea. For example, an animal might have learned through experience to associate a particular scent, such as a predator’s urine, with danger. But each encounter with the smell is likely to be different. Maybe it is mixed with the smell of pine on one occasion and seawater on another. Granule cells provide the brain with an opportunity to filter away the less important odors and to focus sensory neurons only on the salient part of the stimulus.

More here.

According to a New Study, Nothing Can Change an Anti-Vaxxer’s Mind

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Amanda Marcotte in Slate:

While some false beliefs, such as astrology, are fairly harmless, parents who believe falsely that vaccination is dangerous or unnecessary for children present a real public health hazard. That's why researchers, publishing in Pediatrics, decided to test four different pro-vaccination messages on a group of parents with children under 18 and with a variety of attitudes about vaccination to see which one was most persuasive in persuading them to vaccinate. As Chris Mooney reports for Mother Jones, the results are utterly demoralizing: Nothing made anti-vaccination parents more amendable to vaccinating their kids. At best, the messages didn't move the needle one way or another, but it seems the harder you try to persuade a vaccination denialist to see the light, the more stubborn they get about not vaccinating their kids.

Brendan Nyhan of Dartmouth College and his colleagues tested four different messages on parents. Mooney describes them:

The first message, dubbed “Autism correction,” was a factual, science-heavy correction of false claims that the MMR vaccine causes autism, assuring parents that the vaccine is “safe and effective” and citing multiple studies that disprove claims of an autism link. The second message, dubbed “Disease risks,” simply listed the many risks of contracting the measles, the mumps, or rubella, describing the nasty complications that can come with these diseases. The third message, dubbed “Disease narrative,” told a “true story” about a 10-month-old whose temperature shot up to a terrifying 106 degrees after he contracted measles from another child in a pediatrician's waiting room.

The fourth message was to show parents pictures of children afflicted with the diseases they could get without vaccination. Both the pictures and the horrible story about measles increased parental fears about vaccinations.

More here.

Obama the Disappointment

Ken Roth at Human Rights Watch:

Obama-ctPresident Obama has disappointed many by failing to make human rights a priority. True, at times he has stood up for people’s rights where there are few strategic interests at play—in such places as Cote d’Ivoire, Kenya, Venezuela and Zimbabwe. But his readiness to compromise in places like Afghanistan, Egypt, Mexico, Uzbekistan and Yemen leaves the impression that he is not committed to the human rights ideal.

In Fred Kaplan’s view, that makes Obama a realist. But he arrives at that conclusion only by contrasting Obama’s policies with a caricature of idealism. If idealism means the string of Bush-era policies that Kaplan lists—“triumphalism,” “missionary zeal,” “regime-changing wars,” never “negotiating with dreadful rulers”—I would abandon it too. But this is not the 19th century, and foreign policy no longer concerns only relations among sovereigns. After all, idealism was hardly needed when you could buy off an adversary by cutting a deal (or marrying your daughter to its monarch). The world has changed. Or more to the point, our understanding of it has. It can no longer credibly be called “realistic” to pretend that people have no agency beyond the machinations of their rulers, or that we can afford to be indifferent to whether those rulers are autocrats or democrats.

People do matter. As we’ve learned from Ukraine over the past week or the Arab Spring over the past three years or even Russia and China as they meet public demands with a combination of repression and responsiveness, even autocratic governments need to maintain a degree of popular consent to their rule.

More here.

The Dalai Lama’s Ski Trip: What I learned in the slush with His Holiness

Douglas Preston in Slate:

DalaiLamaSkiing.jpg.CROP.original-originalIn the mid ’80s, I was living in Santa Fe, N.M., making a shabby living writing magazine articles, when a peculiar assignment came my way. I had become friendly with a group of Tibetan exiles who lived in a compound on Canyon Road, where they ran a business selling Tibetan rugs, jewelry, and religious items. The Tibetans had settled in Santa Fe because its mountains, adobe buildings, and high-altitude environment reminded them of home.

The founder of the Tibetan community was a man named Paljor Thondup. Thondup had escaped the Chinese invasion of Tibet as a kid, crossing the Himalayas with his family in an epic, multiyear journey by yak and horseback. Thondup made it to Nepal and from there to India, where he enrolled in a school in the southeastern city of Pondicherry with other Tibetan refugees. One day, the Dalai Lama visited his class. Many years later, in Dharamsala, India, Thondup talked his way into a private audience with the Dalai Lama, who told Thondup that he had never forgotten the bright teenager in the back of the Pondicherry classroom, waving his hand and answering every question, while the other students sat dumbstruck with awe. They established a connection. And Thondup eventually made his way to Santa Fe.

The Dalai Lama received the Nobel Peace Prize in 1989. Thondup, who had heard that he was planning a tour of the United States, invited him to visit Santa Fe. The Dalai Lama accepted and said he would be happy to come for a week. At the time, he wasn’t the international celebrity he is today. He traveled with only a half-dozen monks, most of whom spoke no English. He had no handlers, advance men, interpreters, press people, or travel coordinators. Nor did he have any money.

More here.

How prisoners perceive—and misperceive—life in the outside world

Richard_selfportrait_cl_wSabine Heinlein at The Paris Review:

I mailed a copy of my book Among Murderers, about the struggles three men faced when they returned to the world after several decades behind bars, to Richard Robles, a pen pal serving an indeterminate life sentence in New York’s Attica Prison. Prison reading and mailing policies are designed to reinforce the feeling of punishment. Family and friends cannot simply send books; they have to come directly from the publisher or an online bookstore. Most prisons only allow paperbacks—Attica, a rare exception, permits hardcovers. I couldn’t find detailed mailing instructions on Attica’s website, so I called the prison. “Send it through the publisher—and don’t hide no weapon in it,” the employee blurted. Richard wrote me that he almost had to return the book.

[My] name wasn’t on the “buyer’s side” of the invoice. The guard said something about a new rule that prisoners have to buy the book. But as you can see I did get it, after another guard said something to him. Miracles, right?

I did consider it a small miracle when, a few weeks later, I began to receive letters from men who had borrowed the book from Richard. Prison is a dark world far away from ours, and communications travel slowly. We may have forgotten “them,” but they never forget us.

more here.

R.I.P. Alain Resnais, 1922-2014

Over at the Guardian's film blog:

The French director Alain Resnais, who had presented his most recent film The Life of Riley only last month at the Berlin film festival, was part of that remarkable New Wave generation and their associates which set the movie world on fire after the war: not merely film-makers but experimentalists, dazzling theoreticians, maîtres à penser, artists whose work proffered a critique ahead of any of the reviewers and writers who crowded excitably into the cinema to see their latest movies.

His films Night and Fog (1955), Hiroshima Mon Amour (1959) and the sensational Last Year in Marienbad (1961) made him one of the key figures in European cinema. Like many of this group, Resnais made an explosive start and carried on working into extreme old age, though perhaps his later work could not match the scintillation of that golden period of the late 50s and 60s.

He was fascinated not merely in the possibilities of cinema but in theatre and theatricality — and the theatrical dimension of reality. In fact, he was notable as a French cultural star who took an interest in something British: he frequently adapted the plays of Alan Ayckbourn, in whom he savoured a surreality of bourgeois form; he brought out the delicious Magrittean absurdity.

More here. Night and Fog, over at Hulu, for those in the US.

The Texas Miracle That Isn’t

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Phillip Longman in Washington Monthly:

[H]ow much Texas’s growth in jobs just reflects its growth in population. For many decades, Texas has grown much faster in population than the U.S. as a whole, indeed about twice as fast since the 1990s. On its face, there is nothing particularly impressive about a rate of job formation that is just keeping pace with increases in population.

But in the conservative narrative, this population growth is largely driven by individual Americans and businesses fleeing the high taxes and excessive regulation of less-free states. In other words, Texas’s rate of job creation is supposedly more a cause than a consequence of its population growth. If that were true, the Texas boosters would be right to brag. But among the many problems with this story is the reality that, even with an oil boom on, nearly as many native-born Americans are moving out of Texas as are moving in.

For example, according to Census Bureau data, 441,682 native-born Americans moved to Texas from other states between 2010 and 2011. Sounds like a lot. But moving (fleeing?) in the opposite direction were 358,048 other native-born Americans leaving Texas behind. That means that the net domestic migration of native-born Americans to Texas came to just 83,634, which in a nation of 315 million isn’t even background noise. It’s the demographic equivalent of, say, the town of Lawrence, Kansas, or Germantown, Maryland, “voting with its feet” and moving to Texas while the rest of America stays put.

And despite all the gloating by Texas boosters about how the state attracts huge numbers of Americans fleeing California socialism, the numbers don’t bear out this narrative either. In 2012, 62,702 people moved from California to Texas, but 43,005 moved from Texas to California, for a net migration of just 19,697. That’s a population flow amounting to the movement of one village in a continental nation. Far from proving the merits of the so-called Texas model, it shows just how few Californians have seen fit to set out for the Lone Star State, despite California’s high cost of housing and other very real problems.

More here.

meditations on the flood

Floodstory_tabletMarina Warner at The London Review of Books:

Versions of the Flood from around the world record memories of different disasters, not one single universal deluge – this is accepted now even by Biblical scholars. But the different accounts share several dramatic elements: the figure of the one man who is chosen to survive, the extraordinary hope placed in the building of a boat, its measurements and vast size, and the processes of caulking and stocking it. In the Epic of Gilgamesh, the ark is a six-decker vessel; in the Bible, the specs seem so exact they inspired many believers to attempt to make models. Atrahasis is the name of the hero who is spared and wins eternal life in the poem that Ipiq-Aya, Junior Scribe, pressed into the wet clay with his reed pen. In Gilgamesh, the survivor is called Uta-napishti, and Gilgamesh meets him when he is travelling to the underworld in order to bring back from the dead Enkidu,the wild man whom he loves. But the half-divine hero fails, and although he is told how to pick a magic coral-like plant from the seabed, which will guarantee his immortality, he loses it when he is bathing in a pool: a snake comes by and takes it.

The Babylonian Noah tells Gilgamesh how he survived the rains; in Atrahasis he sees in a dream that he must build an ark; in the later Gilgamesh, the counsellor god Enlil whispers the warning in secret:

Load the seed of every living thing into your ark,
The boat that you will build.

(John Gardner’s version, 1984.) The animals do enter two by two in some versions, but here the ark is a sperm bank, a granary.

more here.

Was formalism drilled into American culture at West Point?

Schwabsky_whistlersbattles_ba_imgBarry Schwabsky at The Nation:

Was Whistler just as belligerent toward his art as he was with the wider world into which he sent it? You might think so, judging from reports of how he went about making it: “His movements were those of a duellist fencing actively and cautiously with the small sword,” according to one witness. But no, the results show very little evidence of Whistler’s aggressiveness. Henry Adams can’t have been the only observer to have noticed the contrast between Whistler’s “witty, declamatory, extravagant, bitter, amusing, and noisy” public manner and his art of “nuance and tone,” though perhaps he was one of the few to speculate that it showed how the painter might have been “brutalized…by the brutalities of his world.” That might be putting it a bit too strongly, but still, something must account for Whistler’s conviction that “the Master stands in no relation to the moment at which he occurs—a monument of isolation—hinting at sadness—having no part in the progress of his fellow men.” Whatever the cause of this inner core of loneliness and sorrow, none of Whistler’s biographers, including Sutherland, has ever come close to touching on it. Perhaps that’s just as well, because the beauty of the art transcends its motivating ache—by communicating it in a homeopathic dosage.

But there is something that his art is trying badly to assuage. “Great anomalies are never so great at first as after we have reflected upon them,” Henry James wrote in his 1892 story “The Private Life,” and the anomaly of Whistler is one that keeps growing. Imagine if Giorgio Morandi had written the pugnacious manifestos of F.T. Marinetti.

more here.