Samir S. Patel in Columbia Magazine:
I 1955, Eric Kandel, a New York University medical student training as a psychiatrist, told Columbia University neurophysiologist Harry Grundfest, with whom he was taking a course, that he wanted to find where the id, ego, and superego live in the gelatinous folds of the brain. In Kandel’s recent book, In Search of Memory: The Emergence of a New Science of Mind (W.W. Norton, 2006), he recounts Grundfest’s patient response. “He explained that my hope of understanding the biological basis of Freud’s structural theory was far beyond the grasp of contemporary brain science,” Kandel writes. “Rather, he told me, to understand the mind we needed to look at the brain one cell at a time.”
More here.