Yasemin Saplakoglu in Quanta:
In an instant, the protein folding problem had gone from impossible to painless. The success of artificial intelligence where the human mind had floundered rocked the community of biologists. “I was in shock,” said Mohammed AlQuraishi, a systems biologist at Columbia University’s Program for Mathematical Genomics, who attended the meeting. “A lot of people were in denial.”
But in the conference’s concluding remarks, its organizer John Moult left little room for doubt: AlphaFold2 had “largely solved” the protein folding problem — and shifted protein science forever. Sitting in front of a bookshelf in his home office in a black turtleneck, clicking through his slides on Zoom, Moult spoke in tones that were excited but also ominous. “This is not an end but a beginning,” he said.
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